RE: Fastest finger first6 Nov 2020 04:25
And in the EU from October 2020
Measurement of the HVPG by right hepatic vein catheterisation is the reference technique to assess CSPH. This method is invasive, and can often only be performed in expert centres, limiting its availability. To overcome these limitations, several non-invasive methods have been developed. The most frequently used technique is the liver stiffness measurement (LSM), using transient elastography (TE), which is strongly correlated to HVPG and is useful for the detection of CSPH, including in patients in whom liver resection is indicated.5, 6, 7 LSM-derived scores, such as the LSM-spleen-size-to-platelet ratio score (LSPS), which combines liver stiffness, spleen diameter and platelet count, have been shown to improve the detection of CSPH.8 Nevertheless, LSM has certain well-known limitations, in particular, the rate of unreliable examinations.9
It was recently shown that the diagnostic performance of the quantification of liver surface nodularity (LSN) on routine computed tomography (CT) was good for detecting CSPH and was better than numerous other non-invasive tests.10,11 The quantification of LSN is easy to obtain and can be retrospectively derived from routine CT, which is especially convenient in patients in whom liver resection is being considered.
https://www.jhep-reports.eu/article/S2589-5559(20)30081-1/fulltext