Massive Regenron News30 Sep 2020 03:32
Looks like we’re Barking up the same tree!
Current landscape for COVID-19 neutralising antibodies
Neutralising antibody treatment is seen as a promising form of therapy for COVID-19 and there are a number of groups, alongside Hemogenyx, looking to develop treatments. Regeneron Pharmaceuticals is using its own mouse model system, VelocImmune®, to isolate virus-neutralising antibodies. In June 2020, the company began testing of a treatment, known as REGN-COV2, in Phase 1 trials in both hospitalised and non-hospitalised COVID-19 patients. REGN-COV2 consists of two neutralising Abs which both non-competitively target the S protein. Their rationale of using a ‘****tail’ treatment compared to a single therapeutic approach is to maintain efficacy in the scenario that the virus mutates to escape treatment.
In May 2020, Amgen and Adaptive Biotechnologies partnered to develop a neutralising Ab based on the identification of tens of thousands of naturally occurrin