Member Info for Morgank

Down again

2.7 - 3.00

Over 60m vol on all exchanges so far

92k trade @2.3 was cancelled and re-entered @ 2.4

Another 2.5 mil

48 mil just traded @ mid, best yet

Getting more interesting

Sp rising, yes rising !

Over 17 mil and over 4 mil buy after the close

This time sp rose on a sell

Angle PLC Leading cancer centre publishes Parsortix workflow

Source: RNS Non-Regulatory
TIDMAGL

Angle PLC

04 May 2020


For immediate release 4 May 2020

ANGLE plc ("the Company")

LEADING CANCER CENTRE PUBLISHES PARSORTIX WORKFLOW ADDRESSING PROBLEMS WITH ALTERNATIVE APPROACHES

Workflow for RNA gene expression demonstrated in prostate cancer

Researchers show that "previously undetectable prostate specific transcripts become readily measurable"

ANGLE plc (AIM:AGL OTCQX:ANPCY), a world-leading liquid biopsy company, is pleased to announce that the University of Southern California has published results of new work undertaken in advanced prostate cancer demonstrating a workflow developed using ANGLE's Parsortix(R) system to provide rapid circulating tumor cell (CTC) enrichment and transcriptomic profiling in prostate cancer that is scalable in a cost effective way to large numbers of patient blood samples.

Transcriptomic profiling is the process by which cancer cells, in this case harvested by Parsortix from a simple blood test, are analysed to determine their RNA gene expression to identify how the patient's cancer is developing and evading the immune system so that decisions can be made as to which drug treatments may be most effective for that patient at that time. Standard tissue biopsy is invasive and reflects only a single metastatic site at a single point in time, whereas CTC analyses may reflect multiple metastatic sites and are repeatable allowing the dynamic nature of the cancer to be profiled. This approach enables personalised medicine and addresses the major problem of identifying the right drug at the right time as most drugs only work for a proportion of patients and a "one size fits all" approach is limited in its effectiveness.

The researchers identified key advantages of their Parsortix-based workflow compared to other CTC approaches, as follows:

-- high enrichment levels (high purity of cancer cells with low levels of contaminating white blood cells) for detection of cancer-specific genes over background noise allowing previously undetectable prostate specific transcripts to become readily measurable;

-- minimal manipulation (cancer cells unchanged, alive and not damaged by the process);
-- recovered target cells free of antibodies or magnetic beads (a common problem with antibody-based capture methods avoided by the Parsortix cell separation technique);

-- epitope agnostic (harvests clinically-relevant mesenchymal CTCs as well as epithelial cells);
-- rapid, straight forward and robust workflow;
-- flexible downstream applications.
The research has been published as a peer-reviewed publication in the International Journal of Cancer and may be accessed via https://angleplc.com/library/publications/ .

Associate Professor Amir Goldkorn, M.D., Associate Director for Translational Research

USC Norris Comprehensive Cancer Center & Keck School of Med

Tracking Eye Movements for the Benefit of Pilot Training

Knowing what a pilot or trainee pilot is looking at could be just as important as assessing the outcomes of their actions. This year L3 will be installing the first permanent eye-tracking system into a civil full flight simulator. The technology will help to standardize head-up display flight training which will provide real-time monitoring and post-scenario debrief.
Just highlighting an extract from your link, seeing-2020
‘The implementation of eye tracking technology is a substantial development within the world of pilot training and will provide critical data to better measure, tailor and advance training programs. Going forward it is clear to see the opportunities for this type of technology across a much wider area of pilot training.’

Uber to Design Tech to Check If Drivers Wearing Masks, CNN Says

SEE could do this I’m sure !

There are many applications for See technology, not necessarily in the verticals they are in currently. As long as there are truckers on the road doing long distances this tech is a must. Any public transport requires this tech for safety.
If airlines are to cut costs then maybe the single pilot model will come into being and attention will be critical.
There are many applications in infotainment , gaming Etc
I am still bullish with a slightly longer term view, this virus will be overcome and a virus albeit 12 months off will be a game changer.
Good to see sentiment moving away from autonomous vehicles in the short term so still a need for an attentive driver.

Have you checked SEE.GB for trades they may be there

As long as Lombard hold I am confident and two buys by Kate added to this, shame she bought twice as the sp fell, you can’t accuse her of inside knowledge

A sell and a buy later, not much effort required few seconds, not a bad return for that.
That’s the trouble when there’s not much liquidity the sp can fall quickly with a large trade.
Be interesting to hear other views on this ?
Cheers Tel good research keep it coming, we will be rewarded one day !

Def a sell in the morning and my money has it that the stock was bought back end of day at a lower price for a profit on the day, it makes sense., I think the 2.16 trade was a finger problem

Suspect the 2.5 mil trade this morning was a sell, the market went down
This morning
08:36:39 01-May-2020 2.25 GBX 2,500,000 56,250.00 Off-book LRGS AIMX
08:34:32 01-May-2020 2.25 GBX 11,866 266.99 Off-book AIMX
08:24:00 01-May-2020 2.16 GBX 136,165 2,941.16 Off-book AIMX
08:11:36 01-May-2020 2.26 GBX 100,000 2,260.00 Off-book AIMX
08:05:58 01-May-2020 2.27 GBX 88,119 1,995.90 Off-book AIMX
08:02:14 01-May-2020 2.25 GBX 500,000 11,250.00 Off-book AIMX
08:02:10 01-May-2020 2.25 GBX 444,843 10,008.97 Off-book AIMX

End of day after close late trade reported @Mid seems like a buy back @ a lower price, any one got comments ?

End of trading
Time/date of execution Price Currency Volume Trade value* Trade type Trade flags MIC
17:06:04 01-May-2020 2.20 GBX 2,400,000 52,800.00 Off-book XOFF
16:40:29 01-May-2020 2.20 GBX 475,000 10,450.00 Off-book AIMX
16:08:19 01-May-2020 2.21 GBX 40,000 884.00 Off-book AIMX
16:04:10 01-May-2020 2.17 GBX 5,000 108.50 Off-book AIMX

Nice find Beef