Member Info for Gunner68

Dr John Reader, Chief Scientific Officer of Sareum, commented: "We are pleased to have successfully completed the preclinical toxicology studies and have now received the final report, which will form a key part of the planned CTA application for SDC-1801. We are particularly encouraged that the promising data and progress with the manufacture of SDC-1801 in capsule form continue to support our intention to file the CTA application in mid-year and our plan to begin the first clinical trial with SDC-1801 during H2 2022."
GLA

They said mid 22 which could be up to August so don’t get too excited though if no RNS will be the first month since oct 20 that we’ve not had one .
GLA

Just for information agile funding is for the purpose of assisting PH 1 trials with aim of fast tracking as per RNS 1st July
Dr John Reader, CSO of Sareum, commented:

"The results from our Covid-19 research project are very encouraging and provide clear evidence of the potential of SDC-1801 to reduce the excessive inflammatory response seen in severe Covid-19. We are keen to progress this project to the next stage and will now explore our options to find the best way to fund these next steps. This could include the UK government's AGILE clinical development platform, which was established to fund Phase 1 trials and fast-track the development of potentially ground-breaking Covid-19 treatments. These activities are expected to run in parallel with the broader SDC-1801 development plan targeting autoimmune diseases. We look forward to providing updates on our progress as we reach key milestones in the development of SDC-1801."
IMHO once capsule manufacturer has been completed we may get news then
GLA

Thanks for your reply SOG

SOG do you really think 6 months or have I miss understood I’d say at least 18 months for results to be announced from now we haven’t had confirmation for completion of the capsule and until that is complete no CTA will be filed then another 2 months to be granted and maybe if lucky trials of ph1 will start nov dec and by the time it’s finished and results announced will be another 9 months just look how long the tox results took . Hope I’m wrong but SAR isn’t exactly the rushing type of company and we’ve had 3 months with no word of possible Agile funding
GLA

I’ll be more than happy for you to NOT eat your lab coat
GLA

Just been looking up what months are counted as mid year and this could run up to august so if CTA applied mid year we would be looking at dec for start of PH 1 trial so with CTA already priced in imho unless we receive milestone payments or a deal of sorts what other information would give us a boost or is this the trading price for the rest of the year ?
GLA

Will the CTA already be priced into the SP just like the tox results were ?

June 21st 21 RNS exactly the same not earth shattering but at least some more exposure
GLA
Ps hope he s not doing it from his chair or at least got some oil on it

Done

One day it would be great if we actually released something to time with a good rise to keep momentum going

GLA

How about adding completion of capsule formula and manufacture could be a dark horse

I carnt see that happening without a Ph1 trial in humans being done first but would still like to see Agile funding or other fast track route being taken
GLA

https://r.search.yahoo.com/_ylt=AwrINmAoD0ZiT0IABil0g81Q;_ylu=Y29sbwNpcjIEcG9zAzIEdnRpZAMEc2VjA3Ny/RV=2/RE=1648787368/RO=10/RU=https%3a%2f%2fwww.ncbi.nlm.nih.gov%2fpmc%2farticles%2fPMC3256323%2f/RK=2/RS=wdb8pH2mqbeAywoejZlws85FNrQ-
Tyk2 jak1 could also be another target especially il 12
GLA

Looks like the FT price in old money could be achieved so hopefully will last till after the new tax year and then let the good news roll in
GLA

By mid April I believe Ahfam

I noticed in the last RNS they hadn’t mentioned about possible funding via agile or any of the other programs are they going it alone ?

Great news congratulations

Well the hype over tox RNS was a total flop rise wiped out in one day and again dropping now on a selfish note let’s hope it drops till at least April the 7th to give everyone the chance to top up Isa s or transfere into one no doubt this will rebound and if it is might as well after the 7th
GLA

She carnt do a worse job than peel hunt imho Who is happy with our marketing dept because so far we haven’t seen any