focusIR May 2024 Investor Webinar: Blue Whale, Kavango, Taseko Mines & CQS Natural Resources. Catch up with the webinar here.
Just to add to my post from yesterday with reference to the post from tootight.
Re: "I know the tests started a while back,but 2017 and we are still without the holy grail paperwork"
This press release from By-Health explains the situation a bit.
"BY-HEALTH has been actively innovating in new raw materials, new functions and new technologies through continuous promotion of scientific nutrition strategy, and at the same time committed to the development of products with new functions. The discovery of this new mechanism further unraveled the mystery of Qingluosu" (Fruitflow)", and provided more new ideas for its functional transformation and product landing. With the deepening of scientific research, it is expected to bring more health products with scientific and technological content to the public in the future."
https://www-prnasia-com.translate.goog/story/376755-1.shtml?_x_tr_sl=auto&_x_tr_tl=en&_x_tr_hl=en&_x_tr_pto=wapp
http://www.by-health.com/news-4588
Need to understand German for this one.
"In this podcast we talk about ways to keep your cardiovascular system healthy. dr Mathias Oldhaver, naturopath, health journalist and health expert at Dr. Wolz Zell GmbH answers the following questions from Simone Walther Büel:
- Can you explain to us why cardiovascular diseases are so common in our country? 1:27
- Actually, we all know that these factors that you've just mentioned are unhealthy for us. How can we get out of these harmful habits in everyday life? Do you have any tips? 2:53
- Very important for a healthy cardiovascular system is that our blood vessels remain elastic and blood can circulate freely. Secondary plant substances from fruit and vegetables make an important contribution to this. Can you tell us more about that? 4:17
- Now I can't eat tomatoes and red grapes in huge amounts every day. How can I still use the positive properties of these secondary plant substances? 6:16
- And for whom is it particularly useful to use such a dietary supplement? 6:59"
https://soundcloud.com/ebi-pharm-ag/thromboflow?in=ebi-pharm-ag/sets/ebi-podcasts&utm_source=facebook&utm_medium=post&utm_campaign=social_sharing
https://www.ebi-pharm.ch/wissen/ebi-aktuell/thromboflow-ebi-podcast
By-Health were initially going to launch a product back in 2017.
They then decided to go for Blue Cap and more studies were needed as regulations in China for suppliments changed and got tighter. Finally, probably due to good study results, By-Health decided they wanted to apply for a new health claim that would better suit Fruitflow (and give a better return) on the health claim register. Each step requiring more studies to pass the regulatory hurdles.
As Dr_H says, applying for a new health claim is a new process so we have no idea on timescales.
FF as a drug could well be the next step but lets hope we start seeing revenue before then.
I thought I would make a list of the 8 registered trials (that we know about) in China in order of date.
ChiCTR-POR-17012927 Date of Registration 2017-10-10
Human intervention study on dietary intake of water-soluble tomato extract
https://www.chictr.org.cn/showprojEN.html?proj=22104
ChiCTR1800015987 Date of Registration 2018/05/04
Investigation of the Anti-hypertensive Role of Specific Plant Extracts in Hypertenison Patients
https://www.chictr.org.cn/showprojEN.html?proj=27048
ChiCTR2000034647 Date of Registration 2020/07/13
Effect of combination of Fruitflow and aspirin on platelet function and endothelial cells
https://www.chictr.org.cn/showprojEN.html?proj=56370
ChiCTR2000040559 Date of Registration 2020/12/02
Water-soluble tomato extract improves platelet function in subjects with metabolic syndrome: a randomized clinical trial
https://www.chictr.org.cn/showprojEN.html?proj=64530
ChiCTR2100048885 Date of Registration 2021/07/19
The trial of Xinluosu Tablets effects on human platelet aggregation function
https://www.chictr.org.cn/showprojEN.html?proj=130349
ChiCTR2100054361 Date of Registration 2021/12/15
A human experimental study on the effect of Thomson Beijian Xinluosu Tablets on platelet aggregation function
https://www.chictr.org.cn/showprojEN.html?proj=129186
ChiCTR2300068286 Date of Registration 2023/02/14
Human Trial Effect Evaluation of Xinluosu Tablets in Helping to Maintain Normal Platelet Aggregation Function and Beneficial to Blood Flow Health Function
https://www.chictr.org.cn/showprojEN.html?proj=184552
ChiCTR2300068360 Date of Registration 2023/02/16
Study on the effect of water-soluble tomato concentrate combined with red yeast rice on blood lipid levels in subjects with dyslipidemia
https://www.chictr.org.cn/showprojEN.html?proj=184849
Wellsite, Re: "Now Team DSM (not Sunweb)"
Team DSM is now Team dsm-firmenich with a new kit to match.
https://www.team-dsm.com/tdsmf-launch-pics/
As is the company.
https://www.dsm.com/corporate/investors/dsm-firmenich.html
https://www.dsm-firmenich.com/corporate/home.html
NOVEL COMPOSITIONS
Publication Date
08.06.2023
https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2023099792&_cid=P12-LIO3L8-13133-1
"The present invention relates to novel compositions comprising a retinoid mixture of cis and trans isomers of a retinyl ester, particularly retinyl acetate, with a cis/trans ratio of less than 0.03 as well as the use thereof for the treatment, prevention and lessening of the symptoms of diseases and conditions which can be treated with 5-HT2B serotonin receptor antagonists, including but not limited to diseases or conditions selected from migraine headaches, anxiety, ocular hypotension, heart valve disease, irritable bowel syndrome, and MDMA (commonly called "ecstasy") abuse."
https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2023099792&_cid=P12-LIO3L8-13133-1
"The retinoid mixture and/or pharmaceutical, food, feed or cosmetic composition comprising said mixture according to the present invention with all the definitions and preferences as given herein may be combined with other active ingredients to make a product which has beneficial results. Examples of further active ingredients include Vitamin E, water soluble tomato extract, resveratrol, Vitamin D, 25-hydroxy vitamin D3, hydroxytyrosol, polyunsaturated fatty acids (PUFAs), human milk oligosaccharides, cannabinoids, and mixtures thereof."
Yes I did see that DP64 and thought it was a bit cheeky.
Fruitflow is a registered trademark of Provexis and always has been.
DSM were or maybe still are allowed to use the trademark under licence.
I would assume this product falls under the Premix and Market-Ready Solutions supply agreement with DSM.
BWTFDIK.
Yes.
Probably more than "a single penny" but not as much as when By-Health get the "new permitted health function claim"
"it is currently expected that this would result in some significant orders for Fruitflow, potentially at a multiple of current total sales values."
From Japan this time.
https://shop.fmg-mission.jp/products/?id=ZA0005179
Circu Health From Nutrimax
https://nutrimax.co.id/product/circu-health-nutrimax-30-tablet-selaput/