Member Info for DD77

I top sliced some RR shares at £2.50 to buy in here at 4.25p. That will go down as probably one of the worst trading decisions ever, given RR is now at £8+ and we're at 1p here.

Elsol, you make a valid point..............the only point I would make is I hope John realises that sometimes there are people better placed/skilled to carry out certain tasks and delegating responsibility is not a weakness. If his personal style is affecting business relationships and holding the business back, then he should look at delegating authority to sales managers with remits to grow those relationships, within certain parameters.

This has been a point often made about John, and as the business grows, he needs to avoid micro managing and take a step back and take a more holistic approach. Difficult to let go of certain activities, when it's his 'baby'............I know myself from having run my own business.

John is front and centre of ITX, at the trade shows etc and very well known in the industry. If his style can come across as abrasive, then it would be wise to let others handle customer facing interactions

Lots of chunky buys this morning, nice to see this rising back up

Had an interesting (and very random) convo with a lady whilst I was at my daughter's football training on Saturday. She works for Croda and I mentioned I had an investment in Itaconix, to which she immediately knew well of John Shaw. I won't reveal all details to keep her anonymity, but she did reveal he was particularly awkward to deal with and often asked for more and more money for trials/studies, which they never saw results for (I suspect this was before the recent large fundraise we had here). She did comment that he was probably an excellent entrepreneur but the relationship with Croda became strained, when the relationship holder in Croda , who was a big supporter/advocate, left, and the replacement found him difficult. She thought the US/UK culture perhaps clashed a little.

None of this particularly surprised me, and perhaps not to other LTHs on this board, but I thought it very interesting receiving first hand experience. I have often thought John ran the company like a family business and was probably not very good at delegating/letting go. This needs to happen to allow the company to reach the next level, so I hope John realises and doesn't let his ego get in the way.

She did praise the technical manager at ITX, of which she couldn't remember his name. Said he was English and was highly complimentary.

Anyway, just some Monday morning perusings......

Really good news, on the back of the positive MS data. Who knows the value to Tiziana now, but the potential is enormous!

Tarun Singhal, M.B.B.S., M.D., Director of the PET Imaging Program in Neurologic Diseases, associate neurologist and nuclear medicine physician at Brigham and Women’s Hospital, added: “We have seen a measurable, widespread reduction in microglial PET signal, which is quite remarkable. This reduction is consistent with what has been seen in patients with multiple sclerosis treated with intranasal foralumab. Further studies incorporating additional cases and PET analytical approaches in moderate Alzheimer’s disease, which is an area of huge unmet need, are urgently needed.”

Dr. Ivor Elrifi, CEO of Tiziana Life Sciences, emphasized the significance of these findings: “This PET scan data represents a critical milestone for Tiziana Life Sciences and underscores our commitment to advancing innovative treatments for Alzheimer's disease. With no approved therapies currently available for moderate Alzheimer's, we believe Foralumab holds promise not only as a standalone treatment but also potentially in combination therapies for mild Alzheimer's disease.”

It's not that simplistic as some holders may have losses that they can offset against capital gains tax. Everyone's individual circumstances will be different, but any warrant executed outside an ISA and subsequently sold over 20p will potentially be liable for capital gains tax (above the £3k allowance)

It should be noted that there were 5m warrants outstanding at 20p, which are due to expire on 28th July. Some of these are probably getting flipped, which is acting as a drag on the SP (as well as the delayed orders/news and GH selling)

Leaky

Pretty terrible trading update, not sure what positivity there is

Yes the phase 2 wider scale trial which measures safety efficacy will be the key potential inflection point and could subsequently result in a partnership or licensing agreement for a phase 3 trial.

Really hard to judge value at the moment but end of 2025 if positive could be transformational

Things appear back on track but the lack of commercial traction here is a concern. A hold for me, and I suspect the SP will bounce a little due to the market being reassured but some way to go to get excited

I would add that when Isobel gets revisited, post first oil, this should supercharge the SP as it’ll dwarf sea lion and we could even see a rise to heights of £2.50 which is what I originally bought in at many years ago!

The rise from 12 to 50p has been quite remarkable over the past 5 months, particularly in the absence of any concrete news. Clearly things are afoot though, which makes me wonder how much of FID is now priced in. I think we’ll only see a rise to 60-70p when FID gets announced, with the SP moving into the 80-100p as momentum builds to first oil

Very happy today.

Received £20k redundancy last week. Have stuffed £10k in the new isa and bought at 36.6p this morning. Opportune timing, that’s for sure

Really promising update, only a matter of time before we see an upward shift

Nice to get a clear and transparent RNS on the warrants situation, including outstanding ones.

Might be a little drag on the SP still until end of July, but still expect the SP to continue to rise from this position. The company is now in a strong cash position, with reduced levels of debt

Far more professional and polished delivery, particularly from Laura. Clearly work has been done to improve this. A broadly positive and encouraging outlook

Why don't you email Sam?

I'm sure he'll get around to answering it after he's finished his round of golf

Paul - I also don’t understand why RKH is intending to commission its own independent resource evaluation, unless it’s looking to divest some of its stake.

It’s also strange that RKH have not reviewed the NSAI report.

I need about $4.50 to break even. A long way to go but feels like there’s life in this old dog yet