This evenings Gaurdian part 225 Jan 2022 21:17
Overall, we think that our findings and identification of an immunoglobulin signature will help early identification of patients that are at increased risk of developing long Covid, which in turn will facilitate research, understanding and ultimately targeted treatments for long Covid,” said Onur Boyman, a professor of immunology who led the research.
The team studied 175 people who tested positive for Covid and 40 healthy volunteers who acted as a control group. To see how their symptoms changed over time, doctors followed 134 of the Covid patients for up to a year after their initial infection.
Blood tests on the participants showed that those who developed long Covid – also known as post-acute Covid-19 syndrome (Pacs) – tended to have low levels of the antibodies IgM and IgG3. When Covid strikes, IgM ramps up rapidly, while IgG antibodies rise later and provide longer-term protection.