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Amryt Pharma secures €20m loan from European Investment Bank

Fri, 02nd Dec 2016 08:07

(ShareCast News) - AIM-listed Amryt Pharma has secured a €20m loan from the European Investment Bank to secure its near and mid-term funding for its gel product and a development for a drug compound compound.The loan secures funding for its product Episalvan, which treats skin disorder Epidermolysis Bullosa, and provides capital to progress with the pre-clinical development of an orphan designated acromegaly drug compound, AP 102.The five-year loan's repayment schedule is expected to present a minimal cash burden to the company, as it is split into three tranches, with €10m available immediately and two further tranches of €5m available on reaching of certain milestones in relation to Episalvan.It has 3% interest rate over the Euro Interbank offered rate to be paid periodically, with a further 10% accruing and payable together with the outstanding amount after five years.A phase three clinical trial Epidermolysis Bullosa is expected to start in the first quarter of 2017, with data anticipated to be available in mid-2018 and a commercial launch in 2019.The company recently secured a US patent for Episalvan after it obtained a patent in Europe for the treatment of all partial thickness wounds, including those from Epidermolysis Bullosa, which has a market in the US and Europe to be worth about $1.5bn a year.Andrew McDowell, vice president at European Investment Bank, said: "Continued investment in innovation is crucial to improve lives and build on European strengths to develop world-leading pharmaceutical products. The European Investment Bank is pleased to support innovation and development of new treatment of painful skin disorders by Amryt Pharma."This represents the EIB's first-ever direct support for investment by an Irish pharma company and I am pleased to confirm the EIB's intention to increase support for private sector innovation in Ireland in the years ahead."Chief executive Joe Wiley said that there is currently, there is no available treatment for Epidermolysis Bullosa and he believes that Episalvan has a compelling clinical profile.Sufferers of Epidermolysis Bullosa currently have no treatment options - there are 7,000 known rare diseases but only about 550 orphan drugs have been approved to date.
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30 Mar 2021 12:11

Amryt releases data from Italy lomitapide study

(Sharecast News) - Commercial-stage biopharmaceutical company Amryt Pharma released efficacy and safety data from the 'Lochnes' investigator-sponsored study of lomitapide in familial chylomicronemia syndrome (FCS) on Tuesday, which was conducted by expert lipidologists in Italy.

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29 Mar 2021 09:15

European approval for Amryt's Oleogel-S10 moves closer

(Sharecast News) - Commercial-stage biopharmaceutical company Amryt Pharma announced the validation of its marketing authorisation application for 'Oleogel-S10' by the European Medicines Agency on Monday, for the potential treatment of cutaneous manifestations of junctional and dystrophic epidermolysis bullosa.

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23 Mar 2021 19:03

IN BRIEF: Amryt gets positive feedback on Myalept from US regulator

IN BRIEF: Amryt gets positive feedback on Myalept from US regulator

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23 Mar 2021 09:34

Amryt upbeat on positive FDA feedback

(Sharecast News) - Commercial-stage biopharmaceuticals company Amryt Pharma has received further feedback from the United States Food and Drug Administration (FDA) on Myalept, it said on Tuesday, and its proposed development plan and study design to support an indication for patients with partial lipodystrophy (PL).

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22 Mar 2021 19:07

IN BRIEF: Amryt's Myalepta secures reimbursement approval in France

IN BRIEF: Amryt's Myalepta secures reimbursement approval in France

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22 Mar 2021 09:04

Amryt's Myalepta gets reimbursement approval in France

(Sharecast News) - Commercial-stage biopharmaceuticals company Amryt Pharma announced on Monday that the French Ministry of Social Affairs and Health has approved 'Myalepta', or metreleptin, for reimbursement in the country as an adjunct to diet as replacement therapy.

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15 Mar 2021 16:38

Director dealings: Amryt Pharma chairman makes share purchase

(Sharecast News) - Amryt Pharma revealed on Monday that chairman Ram Stafford had acquired 300,100 ordinary shares in the AIM-listed commercial-stage biopharmaceutical company.

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9 Mar 2021 06:55

IN BRIEF: Amryt, Medison sign distribution deal for Myalepta in Canada

IN BRIEF: Amryt, Medison sign distribution deal for Myalepta in Canada

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8 Mar 2021 12:19

Amryt Pharma signs another distribution deal with Medison

(Sharecast News) - Commercial-stage biopharmaceutical company Amryt Pharma announced the signing of a distribution agreement with Medison Pharma to distribute 'Myalepta' in Canada on Monday.

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4 Mar 2021 12:46

TRADING UPDATES: Origin Enterprises loss slims; Amryt issues guidance

TRADING UPDATES: Origin Enterprises loss slims; Amryt issues guidance

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4 Feb 2021 14:18

Amryt signs multi-regional distribution deals with Medison

(Sharecast News) - Commercial-stage biopharmaceuticals company Amryt Pharma announced the signing of multi-regional distribution agreements with Medison Pharma on Thursday.

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4 Feb 2021 12:14

Amryt Pharma Signs Drug Distribution Agreements With Medison Pharma

Amryt Pharma Signs Drug Distribution Agreements With Medison Pharma

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20 Jan 2021 21:32

IN BRIEF: Amryt Receives Reimbursement Approval For Myalepta

IN BRIEF: Amryt Receives Reimbursement Approval For Myalepta

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23 Dec 2020 19:50

UK TRADING UPDATE SUMMARY: Polarean And Amryt Get US FDA Boost

UK TRADING UPDATE SUMMARY: Polarean And Amryt Get US FDA Boost

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17 Dec 2020 13:38

Amryt gets reimbursement approval for 'Lojuxta' in Saudi Arabia

(Sharecast News) - Biopharmaceutical company Amryt announced on Thursday that Ministry of Health reimbursement approval has been granted for 'Lojuxta', or lomitapide, in Saudi Arabia.

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