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Amryt Pharma secures €20m loan from European Investment Bank

Fri, 02nd Dec 2016 08:07

(ShareCast News) - AIM-listed Amryt Pharma has secured a €20m loan from the European Investment Bank to secure its near and mid-term funding for its gel product and a development for a drug compound compound.The loan secures funding for its product Episalvan, which treats skin disorder Epidermolysis Bullosa, and provides capital to progress with the pre-clinical development of an orphan designated acromegaly drug compound, AP 102.The five-year loan's repayment schedule is expected to present a minimal cash burden to the company, as it is split into three tranches, with €10m available immediately and two further tranches of €5m available on reaching of certain milestones in relation to Episalvan.It has 3% interest rate over the Euro Interbank offered rate to be paid periodically, with a further 10% accruing and payable together with the outstanding amount after five years.A phase three clinical trial Epidermolysis Bullosa is expected to start in the first quarter of 2017, with data anticipated to be available in mid-2018 and a commercial launch in 2019.The company recently secured a US patent for Episalvan after it obtained a patent in Europe for the treatment of all partial thickness wounds, including those from Epidermolysis Bullosa, which has a market in the US and Europe to be worth about $1.5bn a year.Andrew McDowell, vice president at European Investment Bank, said: "Continued investment in innovation is crucial to improve lives and build on European strengths to develop world-leading pharmaceutical products. The European Investment Bank is pleased to support innovation and development of new treatment of painful skin disorders by Amryt Pharma."This represents the EIB's first-ever direct support for investment by an Irish pharma company and I am pleased to confirm the EIB's intention to increase support for private sector innovation in Ireland in the years ahead."Chief executive Joe Wiley said that there is currently, there is no available treatment for Epidermolysis Bullosa and he believes that Episalvan has a compelling clinical profile.Sufferers of Epidermolysis Bullosa currently have no treatment options - there are 7,000 known rare diseases but only about 550 orphan drugs have been approved to date.
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28 Feb 2019 14:06

Redx Pharma Issues 750,000 Shares In Order To Reduce Headquarter Lease (ALLISS)

LONDON (Alliance News) - Biotechnology firm Redx Pharma PLC on Thursday said it has changed the lease agreement at its Alderley Park headquarters in Cheshire, England, reducing the amount of will

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28 Feb 2019 12:12

Amryt Pharma Now Permitted To Enrol Children Under Four In Ease Trial

LONDON (Alliance News) - Amryt Pharma PLC on Thursday said it now has permission to enrol infants and children under four years old in its ongoing phase three Ease trial of AP101 in the Ease will

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7 Jan 2019 09:41

Amryt Pharma Reports Positive Results For Gene Therapy In Skin Disease

LONDON (Alliance News) - Amryt Pharma PLC on Monday reported positive results from two pre-clinical studies of its novel non-viral gene therapy for recessive dystrophic epidermolysis company said

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4 Jan 2019 14:41

Amryt Pharma given go-ahead to continue Phase III EASE trial

(Sharecast News) - Revenue-generating orphan drug company Amryt Pharma announced the results of an unblinded interim efficacy analysis on its pivotal Phase III EASE trial for AP101 as a potential treatment for Epidermolysis Bullosa (EB) on Friday.

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4 Jan 2019 13:32

Committee Recommends Adding More Patients To Amryt Pharma's Ease Trial

LONDON (Alliance News) - Amryt Pharma PLC on Friday said an independent data monitoring committee has recommended adding more patients to its phase three Ease trial of epidermolysis bullosa drug a

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19 Dec 2018 11:22

Amryt Pharma flags slight delay to EASE trial data

(Sharecast News) - Orphan drug company Amryt Pharma updated the market on the global AP101 EASE Phase III clinical trial being conducted in patients with Epidermolysis Bullosa (EB) on Wednesday, reporting that the independent data monitoring committee was scheduled to meet on 21 December to review the EASE unblinded interim efficacy analysis results.

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10 Dec 2018 16:39

Amryt Pharma scores €8.4m grant from Irish government

(Sharecast News) - Amryt Pharma announced on Monday that it has secured am €8.4m grant from the Irish Government for three years of development of its AP103 gene therapy platform.

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10 Dec 2018 12:12

Amryt Pharma Secures Irish Government Grant To Develop AP103 Platform

LONDON (Alliance News) - Amryt Pharma PLC on Monday said it has secured grant funding of EUR8.4 million over three years to develop its AP103 gene therapy platform.Amryt shares were trading

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17 Oct 2018 11:31

Amryt Pharma reaches agreement with French authorities over Lojuxta

(Sharecast News) - Orphan drug company Amryt Pharma has reached agreement with France's Comité économique des produits de santé (CEPS) to reimburse 'Lojuxta' (lomitapide) for the treatment of adult patients with homozygous familial hypercholesterolaemia (HoFH) in France.

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26 Sep 2018 12:47

Amryt Narrows Half Year Loss On Lojuxta Sales And Lower Expenses

LONDON (Alliance News) - Oprhan drug company Amryt Pharma PLC said Wednesday its loss narrowed in the first half of 2018 due to increased sales of its rare disease drug Lojuxta and reduced the six

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2 Aug 2018 12:15

Amryt Pharma Gets Rare Pediatric Disease Designation For AP101

LONDON (Alliance News) - Amryt Pharma PLC said Thursday that the US Food & Drug Administration has granted a rare pediatric disease designation for AP101, used for the treatment of Bullosa is

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19 Jul 2018 12:47

Amryt Pharma Confident In 2018 With Strong First-Half Revenue Growth

LONDON (Alliance News) - Amryt Pharma PLC said on Thursday it expects its performance for 2018 to be in line with current market expectations, following strong trading in the first half.The

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9 Jul 2018 10:46

Amryt Pharma Gets NHS Approval For Cholesterol Drug Lojuxta

LONDON (Alliance News) - Amryt Pharma PLC on Monday said its cholesterol reducing drug, Lojuxta, has been approved by the NHS in England.The pharmaceutical company, which focuses on rare in

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29 May 2018 10:54

Amryt Pharma Gets Four Distribution Deals For Lojuxta In Middle East

LONDON (Alliance News) - Amryt Pharma PLC on Tuesday said it signed four distribution deals for its cholesterol disorder drug Lojuxta across the Middle East.The biopharmaceutical company it

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10 May 2018 13:25

Amryt Pharma Extends Lojuxta Licence Deal Into New Territories

LONDON (Alliance News) - Amryt Pharma PLC on Thursday said it has expanded its Lojuxta licence agreement with Aegerion Pharmaceuticals Inc into Russia, the Commonwealth of Independent States, and

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