Updated investor presentation

25 April 2014

Plethora Solutions Holdings PLC

("Plethora" or the "Company")

Company update

Updated investor presentation

Plethora also announces that Jamie Gibson and Mike Wylie, both members of the management team, will be presenting at the Master Investor Conference being held in London tomorrow.

Accordingly, Plethora has uploaded a presentation onto the Company's website which is now available to view at www.plethorasolutions.co.uk.

-Ends-

Enquiries:

About Plethora:

Plethora is headquartered in the UK and is listed on the London Stock Exchange (AIM: PLE.L). Further information is available at www.plethorasolutions.co.uk.

Plethora is focussed on seeking to launch PSD502 for the treatment of premature ejaculation.

About PSD502 & Premature Ejaculation:

PSD502 is a topical spray for the treatment of premature ejaculation containing lidocaine and prilocaine in a eutectic-like mixture. The Company anticipates launch in 2014.

Premature ejaculation is possibly the most common form of sexual dysfunction in men. Epidemiological studies conducted in the US and in Europe indicate a prevalence of 20 - 30% in men of all ages. There is currently no globally approved and effective pharmaceutical treatment for this condition.

In the absence of any widely approved pharmaceutical therapy with good patient acceptance, the premature ejaculation market offers significant potential for development and growth. An effective drug therapy for premature ejaculation may have a comparable commercial potential to the erectile dysfunction drugs.