Issue of Options

Physiomics plc

(the "Company" or "Physiomics")

Issue of Options

The Company confirms that as part of his contract of employment entered into on 6 December 2010, Physiomics agreed to issue share options to Mark Chadwick, Chief Executive Officer of the Company.

A total of 24,980,625 share options over ordinary shares in the Company ("Options") have now been granted to Mark under the Enterprise Management Initiative Scheme ("EMI"). The options are exercisable at a price of 0.27p each.

The options can be exercised when certain performance conditions are satisfied as defined below:

·; 4,996,125 options are exercisable after 6 June 2011 assuming satisfactory completion by Mark of the first 6 months of his employment at the Company; and

·; the remaining 19,984,500 options are exercisable in tranches of 4,996,125 shares on the satisfaction of commercial conditions intended to achieve pre-defined goals and sustain improvements in company performance. 

If all these options were to be exercised they would represent 2.5% of the current issued share capital of the Company.

Enquiries:

Physiomics plc 

Dr Paul Harper, Chairman

+44 (0) 7747 842446

WH Ireland Limited

Katy Mitchell

+44 (0) 161 832 2174