Issue of Equity

e-Therapeutics plc ('e-Therapeutics' or the 'Company')

Issue of Equity

e-Therapeutics plc (AIM: ETX) announces that it has today issued and allotted 145,000 ordinary

shares of 0.1p each in the Company ('New Ordinary Shares') in order to satisfy the exercise of certain options.

Application has been made to admit the New Ordinary Shares to trading on AIM and dealings in the New Ordinary Shares are expected to commence on 7 February 2011. Following admission the number of ordinary shares in issue in the Company will be 66,153,532.

The above figure (66,153,532 ordinary shares) may be used by shareholders as the denominator for the calculations by which they will determine if they are required to notify their interest in, or a change to their interest in, e-Therapeutics plc under the FSA's Disclosure and Transparency Rules

03 February 2011

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