Blocklisting Six Monthly Return

Ark Therapeutics Group plc

4 December 2012

BLOCKLISTING SIX MONTHLY RETURN

1. Name of applicant

Ark Therapeutics Group plc

2. Name of scheme

Ark Therapeutics Group Unapproved Share Option Scheme

3. Period of return

From 03/06/2012 - 03/12/2012

4. Balance of unallotted securities under scheme from previous return

2,271,252

5. Plus: The amount by which the block scheme has been increased, if the scheme has been increased since the date of the last return (if any increase has been applied for)

Nil

6. Less: Number of securities issued/allotted under the scheme during period

Nil

7. Equals: Balance under the scheme not yet issued/allotted at end of period

2,271,252

BLOCKLISTING SIX MONTHLY RETURN

1. Name of applicant

Ark Therapeutics Group plc

2. Name of scheme

Ark Therapeutics Group Enterprise Management Incentive Share Option Plan

3. Period of return

From 03/06/2012 - 03/12/2012

4. Balance of unallotted securities under scheme from previous return

939,433

5. Plus: The amount by which the block scheme has been increased, if the scheme has been increased since the date of the last return (if any increase has been applied for)

Nil

6. Less: Number of securities issued/allotted under the scheme during period

Nil

7. Equals: Balance under the scheme not yet issued/allotted at end of period

939,433

BLOCKLISTING SIX MONTHLY RETURN

1. Name of applicant

Ark Therapeutics Group plc

2. Name of scheme

Ark Therapeutics Group 2005 Long Term Incentive Plan

3. Period of return

From 03/06/2012 - 03/12/2012

4. Balance of unallotted securities under scheme from previous return

683,200

5. Plus: The amount by which the block scheme has been increased, if the scheme has been increased since the date of the last return (if any increase has been applied for)

Nil

6. Less: Number of securities issued/allotted under the scheme during period

Nil

7. Equals: Balance under the scheme not yet issued/allotted at end of period

683,200

BLOCKLISTING SIX MONTHLY RETURN

1. Name of applicant

Ark Therapeutics Group plc

2. Name of scheme

Ark Therapeutics Group Approved Share Option Plan

3. Period of return

From 03/06/2012 - 03/12/2012

4. Balance of unallotted securities under scheme from previous return

1,000,000

5. Plus: The amount by which the block scheme has been increased, if the scheme has been increased since the date of the last return (if any increase has been applied for)

Nil

6. Less: Number of securities issued/allotted under the scheme during period

Nil

7. Equals: Balance under the scheme not yet issued/allotted at end of period

1,000,000