Block Listing Six Monthly Return

Name of applicant:

Circassia Pharmaceuticals plc

Name of scheme:

Circassia EMI Share Option Scheme

Period of return:

From:

1st July 2017

To:

31st December 2017

Balance of unallotted securities under scheme(s) from previous return:

1,236,125

Plus: The amount by which the block scheme(s) has been increased since the date of the last return (if any increase has been applied for):

-

Less: Number of securities issued/allotted under scheme(s) during period (see LR3.5.7G):

(535,375)

Equals: Balance under scheme(s) not yet issued/allotted at end of period:

700,750

Name of applicant:

Circassia Pharmaceuticals plc

Name of scheme:

Circassia 2007 Unapproved Share Scheme

Period of return:

From:

1st July 2017

To:

31st December 2017

Balance of unallotted securities under scheme(s) from previous return:

203,000

Plus: The amount by which the block scheme(s) has been increased since the date of the last return (if any increase has been applied for):

-

Less: Number of securities issued/allotted under scheme(s) during period (see LR3.5.7G):

-

Equals: Balance under scheme(s) not yet issued/allotted at end of period:

203,000

Name of applicant:

Circassia Pharmaceuticals plc

Name of scheme:

Circassia 2014 Performance Share Plan Scheme

Period of return:

From:

1st July 2017

To:

31st December 2017

Balance of unallotted securities under scheme(s) from previous return:

491,775

Plus: The amount by which the block scheme(s) has been increased since the date of the last return (if any increase has been applied for):

-

Less: Number of securities issued/allotted under scheme(s) during period (see LR3.5.7G):

(365,074)

Equals: Balance under scheme(s) not yet issued/allotted at end of period:

126,701

Name of contact:

Julien Cotta

Telephone number of contact:

01865 405 560