Analysts call on Santander Mexico tender offer

Banco Santander, S.A. ("Banco Santander" or the "Bank"), in compliance with the Securities Market legislation, hereby communicates the following:

OTHER RELEVANT INFORMATION

Banco Santander hereby advises that today, Friday 26 March 2021, a presentation will take place to analysts through a conference call at 10:00 am hours (Madrid time) regarding the Bank's intention to make an offer to acquire all shares of Banco Santander (Mexico), S.A. ("Santander Mexico") not already held by the Santander Group, representing c. 8.3% of Santander Mexico's share capital.

To follow the presentation to analysts it is necessary the registration using the following link. Once registered details on the telephone number of the conference call and passcode will be provided.

https://cossprereg.btci.com/prereg/key.process?key=P7NAQXUXM

Likewise, the document to be used at the presentation to analysts will be made public prior to its commencement via its notification to the CNMV and publication on Santander's corporate website www.santander.com.

Boadilla del Monte (Madrid), 26 March 2021