SKIN.L Regulatory News (SKIN)

Integumen plc

("Integumen" or the "Company")

Integumen strengthens intellectual property portfolio

Integumen (LSE: SKIN), the personal health care company developing and commercialising technology and products for the human integumentary system, is pleased to provide an update on its patents and trademarks.

The Company has received:

· a Notice of Allowance ("NOA") for the trademark "Clarogel" in the United States of America, an anti-microbial formulation of usnic acid which is a late stage product designed for blemish control. Since it has received the NOA, Integumen intends to apply for the trademark registration of Clarogel in the United States of America with immediate effect.

· a NOA for its base Visible Youth patent in Canada, for the cosmetic composition for the treatment of skin. These compositions include the combination of Hyaluronic acid and bioactive glass powder which form the basis of Integumen's line of Visible Youth products, a range of cosmeceuticals targeting the anti-ageing market.

· a patent in the United States for the manufacture and sale of TS1, a tongue vacuum cleaner.

Clarogel™

Clarogel is an anti-microbial formulation of usnic acid which is a late stage product designed for blemish control. The Company's copper salt of usnic acid is a synthetic derivative of a compound which is found naturally in lichen. It is a permitted cosmetic ingredient in the EU and US with anti-microbial and anti-inflammatory properties. Clarogel was subject to a clinical study in 2011 against a market leading product and demonstrated a greater reduction in inflamed lesions than the comparator after one month of use, and was responsible for significant reductions in sebum excretion*. Integumen is in the process of altering the formulation of Clarogel to improve scent, colour and stability issues evident in the original product.

Integumen is the registered owner of a trademark for Clarogel in the EU.

* Source: Clearasil Product Sales Analysis, Evaluate Pharma, Evaluate Limited, www.evaluate.com

Visible Youth™ 

Visible Youth Consumer and Visible Youth Professional are a consumer and professional range of

'cosmeceuticals' targeting the anti-ageing market. Steeped in evidence-based science, Visible Youth Professional and Consumer skin care products contain the optimal size, purest and most effective Hyaluronic acid molecular fraction and Bioactive Vitryxx®* for deep-penetrating hydration. The unique line of proprietary formulations helps restore the skin's natural supply of HA-water complex, resulting in long-lasting benefits for all skin types.

A NOA is a written notification from the U.S. Patent and Trademark Office that a specific trademark has received no opposition from being registered following publication in the Official Gazette. Once a NOA has been received, an applicant is then permitted to file for the registration of the trademark.

TS1™

TS1 is a disposable tongue vacuum cleaner for professional use in the dental surgery. The product is a two-component plastic device which has two active sides, a knobby back to massage the tongue and break the biofilm and an open lamella front to clean the tongue by removing plaque. The tongue vacuum cleaner is simply attached to the saliva ejector tube, which is connected to the vacuum unit of the dentist chair. The size of saliva ejectors is standardised and universally found in dental surgeries.

Declan Service, CEO of Integumen, said:

"These trademarks and patents are highly valuable additions to our intellectual property portfolio and a positive step forward as we seek to generate value through distribution partners or licence agreements."