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Exercise of Warrants & Issue of Ordinary Shares and Total Voting Rights

21 Sep 2020 11:00

Exercise of Warrants & Issue of Ordinary Shares and Total Voting Rights

AMRYT PHARMA PLC

(“Amryt” or the “Company”)

Exercise of Warrants & Issue of Ordinary Shares and Total Voting Rights

DUBLIN, Ireland, and Boston MA, September 21 2020, Amryt (Nasdaq: AMYT, AIM: AMYT), a global, commercial-stage biopharmaceutical company dedicated to developing and commercializing novel therapeutics to treat patients suffering from serious and life-threatening rare diseases, announces that an institutional investor has exercised subscription rights relating to 4,229,753 zero cost warrants (the “Warrants”).

These Warrants were issued in September 2019 as part of the Company’s acquisition of Aegerion. Certain institutional investors elected to receive Warrants to subscribe for new ordinary shares of £0.06 each (“Ordinary Shares”), in place of the same number of Ordinary Shares, as consideration for the Company’s acquisition of Aegerion and their equity investments in the Company in September 2019. Each warrant entitles the holder to subscribe for one Ordinary Share for no additional consideration. 

In order to satisfy the exercise of the Warrants, the Company will issue 4,229,753 ordinary shares of £0.06 each (the “New Ordinary Shares”) to the institutional investor. It is expected that admission to trading of the New Ordinary Shares on AIM will become effective, and that dealings in the New Ordinary Shares will commence at 8.00 a.m. BST on 22 September 2020.

On admission of the New Ordinary Shares, the issued share capital of the Company will comprise 167,593,296 Ordinary Shares. The Company holds 4,864,656 Ordinary Shares in treasury. Therefore, the total number of voting rights in the Company is 162,728,640. This figure may be used by shareholders as the denominator for the calculation by which they will determine if they are required to notify their interest in, or a change to their interest in, the Company under the FCA’s Disclosure Guidance and Transparency Rules. The Company will also have in issue 8,966,520 zero cost warrants.

Enquiries:

Amryt Pharma plc+353 (1) 518 0200
Joe Wiley, CEORory Nealon, CFO/COO 
 LifeSci Advisors, LLC+1 (212) 915 2564
Tim McCarthy 
 Consilium Strategic Communications+44 (0) 20 3709 5700
Amber Fennell, Matthew Neal, Ashley Tapp 

About Amryt

Amryt is a biopharmaceutical company focused on developing and delivering innovative new treatments to help improve the lives of patients with rare and orphan diseases. Amryt comprises a strong and growing portfolio of commercial and development assets.

Amryt’s commercial business comprises two orphan disease products.

Juxtapid®/ Lojuxta® (lomitapide) is approved as an adjunct to a low-fat diet and other lipid-lowering medicinal products for adults with the rare cholesterol disorder, Homozygous Familial Hypercholesterolaemia ("HoFH") in the US, Canada, Columbia, Argentina and Japan (under the trade name Juxtapid®) and in the EU (under the trade name Lojuxta®). HoFH is a rare genetic disorder which impairs the body's ability to remove low density lipoprotein ("LDL") cholesterol ("bad" cholesterol) from the blood, typically leading to abnormally high blood LDL cholesterol levels in the body from before birth - often ten times more than people without HoFH - and subsequent aggressive and premature cardiovascular disease.

Myalept® / Myalepta® (metreleptin) is approved in the US (under the trade name Myalept®) as an adjunct to diet as replacement therapy to treat the complications of leptin deficiency in patients with congenital or acquired generalized lipodystrophy (GL) and in the EU (under the trade name Myalepta®) for the treatment of leptin deficiency in patients with congenital or acquired GL in adults and children two years of age and above and familial or acquired partial lipodystrophy (PL) in adults and children 12 years of age and above for whom standard treatments have failed to achieve adequate metabolic control. Metreleptin is also approved for lipodystrophy in Japan. Generalised and partial lipodystrophy are rare disorders characterised by loss or lack of adipose tissue resulting in the deficiency of the hormone leptin, produced by fat cells and are associated with severe metabolic abnormalities including severe insulin resistance, diabetes, hypertriglyceridemia and fatty liver disease.

Amryt's lead development candidate, FILSUVEZ® is a potential treatment for the cutaneous manifestations of EB, a rare and distressing genetic skin disorder affecting young children and adults for which there is currently no approved treatment. In September 2020, Amryt reported positive top line results from its pivotal global phase 3 trial of FILSUVEZ® in EB. The primary endpoint of the trial was met (p-value = 0.013). FILSUVEZ® has been granted Rare Pediatric Disease Designation and has also received a Fast Track Designation from the U.S. Food and Drug Administration. The global market opportunity for EB is estimated by the Company to be in excess of $1.0 billion.

In March 2018, Amryt in-licenced a preclinical gene-therapy platform technology, AP103, which offers a potential treatment for patients with Dystrophic Epidermolysis Bullosa, a subset of EB, and is also potentially relevant to other genetic disorders. 

For more information on Amryt, including products, please visit www.amrytpharma.com.

This announcement contains inside information for the purposes of article 7 of the Market Abuse Regulation (EU) 596/2014.

The person making this notification on behalf of Amryt is Rory Nealon, CFO/COO and Company Secretary.

Financial AdvisorsShore Capital (Edward Mansfield, Daniel Bush, John More) are NOMAD and Joint Broker to Amryt in the UK. Stifel (Ben Maddison) are Joint Broker to the company in the UK. Davy (John Frain, Daragh O’Reilly) act as Joint Broker to the company.

Forward-Looking Statements Statements in this announcement with respect to Amryt's business, strategies, timing for completion of and announcing results from the EASE trial, the potential impact of closing enrollment in the EASE trial, as well as other statements that are not historical facts are forward-looking statements involving risks and uncertainties which could cause the actual results to differ materially from such statements. Statements containing the words "expect", "anticipate", "intends", "plan", "estimate", "aim", "forecast", "project" and similar expressions (or their negative) identify certain of these forward-looking statements. The forward-looking statements in this announcement are based on numerous assumptions and Amryt's present and future business strategies and the environment in which Amryt expects to operate in the future. Forward-looking statements involve inherent known and unknown risks, uncertainties and contingencies because they relate to events and depend on circumstances that may or may not occur in the future and may cause the actual results, performance or achievements to be materially different from those expressed or implied by such forward-looking statements. These statements are not guarantees of future performance or the ability to identify and consummate investments. Many of these risks and uncertainties relate to factors that are beyond each of Amryt's ability to control or estimate precisely, such as future market conditions, the course of the COVID-19 pandemic, currency fluctuations, the behaviour of other market participants, the outcome of clinical trials, the actions of regulators and other factors such as Amryt's ability to obtain financing, changes in the political, social and regulatory framework in which Amryt operates or in economic, technological or consumer trends or conditions. Past performance should not be taken as an indication or guarantee of future results, and no representation or warranty, express or implied, is made regarding future performance. No person is under any obligation to update or keep current the information contained in this announcement or to provide the recipient of it with access to any additional relevant information that may arise in connection with it. Such forward-looking statements reflect the Company’s current beliefs and assumptions and are based on information currently available to management.

Date   Source Headline
7th Jan 20197:00 amRNSPositive results for gene therapy AP103
4th Jan 201912:56 pmRNSEASE Phase III trial interim efficacy results
21st Dec 20182:05 pmRNSSecond Price Monitoring Extn
21st Dec 20182:00 pmRNSPrice Monitoring Extension
19th Dec 20187:00 amRNSUpdate on ongoing AP101 Trial
10th Dec 201811:30 amRNSGrant Funding from Irish Government for AP103
17th Oct 20187:00 amRNSLojuxta to be reimbursed in France
26th Sep 20187:00 amRNSInterim Results
14th Sep 20187:00 amRNSNotice of Results
10th Sep 20187:00 amRNSAmryt receives IND approval from FDA for AP101
2nd Aug 20187:00 amRNSFDA grants Pediatric Rare Disease designation
19th Jul 20187:00 amRNSTrading update & significant momentum building
9th Jul 20187:00 amRNSNHS England approves funding for Lojuxta
6th Jul 20187:00 amRNSChange of Registered Address
25th Jun 20188:10 amRNSCompany name alteration for previous release
25th Jun 20187:00 amRNSPositive data of Pollinex Quattro Grass vaccine
5th Jun 201810:41 amRNSResult of AGM
29th May 20187:00 amRNSFour Middle East Lojuxta® Distribution Agreements
10th May 20187:00 amRNSExclusive Lojuxta® Licence Expanded
9th May 20182:48 pmRNSHolding(s) in Company
8th May 20187:00 amRNSHolding(s) in Company and Lock-in agreement
4th May 20187:00 amRNSPosting of Annual Report 2017 and Notice of AGM
17th Apr 20187:00 amRNSFinal Results
15th Mar 20187:00 amRNSTrading update & Gene therapy agreement
6th Mar 20187:00 amRNSSenior Management Appointment
6th Mar 20187:00 amRNSDistribution Agreement for Lojuxta in Middle East
2nd Mar 20187:00 amRNSNotice of Trading Update
30th Jan 20187:00 amRNSNew Distribution Agreement Signed
24th Jan 20187:00 amRNSSenior Management Team Appointment
10th Jan 20187:00 amRNSNew Distribution Agreement Signed
8th Jan 20187:00 amRNSDistribution Agreement Signed Covering Switzerland
20th Dec 20177:00 amRNSSenior Management Team Appointment
1st Dec 20177:00 amRNSGrant of Options & PDMR Dealings
20th Nov 20174:35 pmRNSPrice Monitoring Extension
13th Nov 20177:00 amRNSDistribution Agreement Signed in Saudi Arabia
13th Oct 20173:29 pmRNSHolding(s) in Company
11th Oct 20177:00 amRNSHolding(s) in Company
11th Oct 20177:00 amRNSDirector Share Purchases
11th Oct 20177:00 amRNSEnterprise Securities Market Notice
10th Oct 20177:00 amRNSEnterprise Securities Market Notice
9th Oct 201712:13 pmRNSResult of General Meeting & Completion of Placing
21st Sep 20177:00 amRNSPlacing to raise EUR 15m
4th Sep 20177:00 amRNSInterim Results
31st Aug 20177:00 amRNSAttendance at Rodman & Renshaw Conference
30th Aug 20177:00 amRNSSenior Management Appointment
23rd Aug 20178:30 amRNSNotice of Results
25th Jul 20177:00 amRNSHighly positive long-term study results - Lojuxta
25th May 201711:49 amRNSResult of AGM
25th May 20177:00 amRNSAGM Statement
27th Apr 20177:00 amRNSStudy Results of Real-World Experience of Lojuxta

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