1119 ISE Delisting announcement

Company Announcement

For immediate release

22 January 2018

NOTICE OF DELISTING

Santander UK plc (the "Issuer")

This notice relates to the following N&C Securities issued by the Issuer under its Note, Certificate and Warrant Programme base prospectus dated 14 December 2016 and the supplements to the base prospectus dated 8 March 2017, 10 October 2017, 21 August and 9 November 2017 (together, the "Base Prospectus"):

£20,000,000 Equity Index Linked Notes due January 2024 (the "N&C Securities") issued on 27 October 2017 pursuant to the Final Terms dated 27 October 2017 (the "Final Terms").

Notice is hereby given that, as of the date of this notice, the Issuer shall delist N&C Securities in a principal amount of £16,031,518 and that consequently following the delisting the aggregate principal amount of the N&C Securities issued will be reduced to £3,968,482 (the "Outstanding N&C Securities").

For further information, please contact:

Structured Notes Desk

Tel: +44 (0) 20 7756 7000 or structurednotesafm@santander.co.uk.

DISCLAIMER - INTENDED ADDRESSEES

Please note that the information contained in the Base Prospectus and Final Terms may be addressed to and/or targeted at persons who are residents of particular countries (specified in the Base Prospectus and/or the Final Terms) only and is not intended for use and should not be relied upon by any person outside these countries and/or to whom the offer contained in the Base Prospectus and/or the Final Terms is not addressed. Prior to relying on the information contained in this notice, the Base Prospectus and/or the Final Terms, you must ascertain from the Base Prospectus and/or the Final Terms whether or not you are part of the intended addressees of the information contained therein.

Your right to access this service is conditional upon complying with the above requirement.

Neither the Base Prospectus nor the Final Terms referenced herein constitutes an offer of securities for sale in the United States. The securities described herein have not been, and will not be, registered under the U.S. Securities Act of 1933, as amended (the "Securities Act"), or under any relevant securities laws of any state of the United States of America, and may not be offered or sold to U.S. persons or to persons within the United States of America, except pursuant to an exemption from the Securities Act.

This announcement has been issued through the Companies Announcement Service of

the Irish Stock Exchange.

END