Member Info for Tim45

I've been trying to find an old post on here which explained why AZN terminated the SNG001 deal they struck up in 2014 with Synairgen.
Is there a way to search for key words in a post title? If there is, I can't see it! Or maybe it's a 'Premium Chat" feature?
Google searches show that a 2014 asthma treatment trial of SNG001 was stopped due to an insufficient number of severe cases. I am highly optimistic that SNG001 will produce the P3 data needed to bring this great treatment to patients globally but I am still curious as to what soured AZN's interest back then?

Thanks Robort - very good of you.

LargeGin - ah, thank you! I thought I was going mad. I had always assumed that the on-line version was a full copy of the printed paper but apparently not ... what else am I missing?

Sorry, I still can't see this article in the on-line version of thr ST. Either it's me (quite likely) or the piece is only in the printed copy. Anybody else found it in the online version?

I can't find this in the on-line version.

TipTop - you’ll find everything you need to know on the excellent Reddit/Synairgen page, compiled by people on this BB who actually know what they’re talking about.

Thanks Only1Ranger - for your balanced, mature summary of the world we now face. Sorry to hear of your predicament but very best wishes to you and your family.

This is the clearest, down-to-earth explanation of how this devious virus inhibits the production of interferon. Thanks for reminding us of it. Phase 3 trial data is everything.

I thought I heard him pay tribute to 'British scientists and new treatment"?

What a sloppy, lazy piece ... 'The treatment is undergoing Phase II trails ...'. No mention of Phase III trial. Idiots.

"Beforegold" ... thank you Freud.

Sorry Beforegold and Oxford - that's my mistake. Even better than I had thought then.

BeforeGolf - I thought the device he showed fits into the mask of someone already on oxygen (at OSC level 4) rather than the far more serious patients who are actually being ventilated?

That's perfect, many thanks Joey. 'Trials Register' site now bookmarked. So much data on there!

I'm still confused by the Phase III trial scope - what is the concensus? Maybe more will be revealed in this afternoon's NIHR Zoom meeting. Apologies if already discussed and resolved, and I missed it. (So many posts on here)

1. NIHR supported the Phase II trial and is supporting Phase III trial: "The phase 3 trial is expected to involve 900 participants and will take place across up to 20 NHS sites." from their own web site today)

2. Paraxel is working with Synairgen to run Phase III trials globally "... the trial is expected to enroll 900 patients across approximately 20 countries ..." from their own web site, Oct 20.

So ... to me this definitely means there are TWO separate Phase III arms which has to be a good thing. Hopefully the UK trials will be soon underway and our hospitals will realises just what a tool they have available to prevent many patients progressing to ventilators.

Your thoughts?

Thanks Org30 - background I wasn't aware of.

Org30 - not quite: The court ruled that the crash was caused by a piece of metal left on the runway after falling from a Continental jet and which had been missed during a visual runway inspection. Investigators said this caused a tyre-burst in the Concorde, which in turn ruptured a fuel tank.
As a result airports were required to install radar systems that detect such Foreign Object Debris (FOD)

Just a reminder, I couldn't find the original BB post. Sounds interesting.
Title: "COVID-19: Translating immune understanding and collaboration into new therapeutic strategies: Interferon beta story"

You can register at: https://ccf-nihr.zoom.us/webinar/register/WN_KZLwXfmUQaS3Cu0-UU48Zw

Greenlabel - many thanks for your help, I should have done more research first!

Odd how Synairgen web site has no emails at all?

Thanks Doc - oh dear, I missed those details.