RE: Week ahead25 Jul 2020 18:28
yes DAM, well wort a proper read of the full abstract from SRI..
the last part of it caught my eye
the impact and what it all mean
What was the impact on the development of the principal discipline(s) of the project? We have evidence of reducing pathogenic auto-antibodies in mouse model of lupus without effecting the normal balance of the immune cell subsets. This approach is novel and may lead to development of a therapy for lupus which doesn’t involve systemic immuno-suppression with harmful side effects.
What was the impact on other disciplines?
Since the compounds can block Th17 associated cytokines (e.g. IL-6 and IL-23), these results could influence treatments aimed at other Th17 mediated diseases, such as arthritis and psoriasis.
What was the impact on technology transfer? Nothing to report
What was the impact on society beyond science and technology?
This approach may open up additional treatment approaches for lupus. The standard of care is little changed in 50 years, so there is a need for new treatment options. Lupus particularly targets women in their most productive years (child bearing age) of life. Our results, though not very conclusive and only based of short-term treatment, have significant indications that our approach can be used as a therapeutic target in a chronic disease like lupus and may have positive outcomes. Our current approach may benefit numerous lupus patients and improve their quality of life and productive contribution to society.
very big endorsement that the compound work but need more study..
as that DOCTOR from India visa run out by all account
and he needed another 3 month to see the long term benifit
308..
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