Member Info for jackdaw99

A highly effective malaria vaccine has been recommended for widespread use by the World Health Organization.

The R21/Matrix-M vaccine, developed by the University of Oxford, is only the second malaria vaccine to be recommended by the WHO. It is the first to meet the WHO’s target of 75% efficacy. Malaria, a mosquito-borne disease, claims half a million lives every year and mostly affects children under the age of five, and pregnant women. “As a malaria researcher, I used to dream of the day we would have a safe and effective vaccine against malaria. Now we have two,” said Dr Tedros Adhanom Ghebreyesus, director general of the WHO. Demand for vaccines is huge. However, available supplies of the RTS,S vaccine, the first malaria vaccine approved by the WHO in 2021, are limited. A second WHO-recommended vaccine is expected “to protect more children faster, and to bring us closer to our vision of a malaria-free future,” said Tedros.

The RTS,S vaccine will be available in some African countries in early 2024 and the R21 malaria vaccine is expected to become available to countries in mid-2024. The world’s largest vaccine manufacturer by doses – the Serum Institute of India – is already lined up to make more than 100m doses a year and plans to scale up to 200m a year, the BBC reported. Each dose costs between $2 and $4; four doses are needed per person. That is about half the price of RTS,S. So far, there are only 18m doses of RTS,S. (Guardian)

Keep calm & Carry on?

From Kernowlad: "And it continues. I wish I had Jackdaw's optimism but I don't.

Unless they pull something out of the bag at the interims this will continue to drift downwards - or even faster possibly.

Where is the value?"

I think they did?

...or someone wants in cheap?

Yes. Did someone recently say "Mind the Gap"?

Yes, obviously high risk but, if it comes good, any deal could be huge.

"...It could easily be at new 3 year highs by the end of the week…..those who keep selling because they expect a pullback because “thats what usually happens’ may miss out…...." Yes. And now they are being encouraged because someone still needs to buy? Acceleration after lunch IMO.

Last big volume was almost 5 million back in November 2022. Looks like that might be beaten today.

.. and now price seems to have its second wind! Amazing and welcome.

To me this volume indicates a deal is afoot and known, rather than just pre-conference excitement, but who knows!

...being shown by those who have wanted the price lower for months now. But why. To coin two cliches, methinks we shall see (ie in a few days).

Doesn't 'mental health care" = socialism?

" ... scancell just can’t run a muck doing what it likes " It's 'run amok', a term from Malaysia, when young, male loonies would go crazy and kill people in the streets. A bit like the current USA.

And yes, a government grammar school ;-), selected by IQ rather than selected by wallet??

Ahananda, Doctorate in biology from Oxford Uni. Which call centre do you work at?

A vaccine cannot prevent infection, only reduce the magnitude of that infection, which is all it need do in most cases.

Disingenuous. Can you name a vaccine that does either or both? What vaccines do is sensitise your immune system against a 'real' infection that you have not yet met, in effect simulating a natural disease with a less-dangerous 'artificial' version. This means that, when you meet the 'real' thing you will mount not a primary (=slow) immune response but a much faster and stronger (=secondary) immune response. So you become less ill. A vaccine does not prevent you being infected with the real disease, nor does it prevent you either infecting nor becoming infected by others. So, while it is true that no vaccine 'stops' spread or infection by its primary effect, they reduce the effects of an infection and, by doing so, may have consequences upon both (eg by getting on top of an infection rapidly, because of strong secondary response, there may be fewer transmissible virus/bacterium particles to infect others). Hope that helps.

It's worse than that really, as cancer evolves WITHIN a patient, making changes sometimes very rapidly indeed. Interesting BBC podcasts available ATM if you want more details.

"The current vaccines neither stopped the infection or the spread " Not really true that, however much you would like SCLP to succeed.

It's always nice to get a methinks. Waited a long time but today we bagged one. Hopefully while wearing a codpiece and drinking mead.