Member Info for Bothwell

Hello Bignose, will you be happy with China approval? Where do you see the SP after this happens.

You are correct.

The type of 3 month study would be circa 100 patients at a fully absorbed cost of 5000 per patient, or so. There aren’t any complicated evaluations involved. Costing based on studies previously carried out over longer terms for US approval.

I really hope they use the China approval income to spend on getting FDA approval in the US and keep the company going rather than another share dilution. Fairs, fair…..

Notification will be soon…

It will be interesting to see how the SP reacts on approval.

I have been told China approval will be soon! No date.

The dilutions have killed the private shareholders. We would have all been breakeven if it didn’t happen and I know we needed the cash input but surely a load would have been better for us but JM gave us a lifeline and put the money in. I am guessing Jamie and the rest of the Directors suffered the same as us. 10 shares to 1.

Dr Mike Wyllie still on board, think he had success with a few drugs in US!!! Just saying.

I am down well into £000,000 due to dilution which is really hard to take, the mistakes by the BoDs have really hurt the private shareholders.

China is happening laddie!!!

$7 million before tax received on China approval and first commercial sale.

It’s only a thought but will they use the money they receive from China approval to pay for the FDA study which will then give us approval in both countries with no further dilution?

Bignose; it is this part that hurts us the most not the time.

And then Jim had to loan the company 10mill to get it across the line which shareholders ultimately paid for from ***dilution***. So you have to excuse my negativity.

FDA. RP just need to commit some money for a 3 month study which would be circa 100 patients at a fully absorbed cost of 5000 per patient. There aren’t any complicated evaluations involved. Costing based on studies previously carried out over longer terms.

China NDA isn’t far away.

I wonder how the SP reacts to China approval and have we been waiting on this before US approval.

I do think China isn’t far away from approval.

Why is Fortacin not readily available online? Out of stock?

Researchgate 2025

The only so far officially approved medication-dapoxetine-is characterized by high discontinuation rates of up to 90%, mostly because of high side effects, cost issues, efficacy below expectations, and the need for scheduling sexual intercourse. Conclusion: With the official approval in Europe the new dose-metered lidocaine-prilocaine spray (Fortacin) may become a real first-line therapy option for PE and may offer a satisfactory and affordable solution, especially because of its unique galenic preparation, making its handling easy and customer friendly. In addition, it has the potential to significantly increase the currently low patients' acceptance of available monotherapies and become an established second-line therapy for the severe PE patients with IELTs

Do you think there was a need to dilute our shareholding 10/1, could they have not put in a loan instead of harming the shareholders?

It is unreal to think we would have been breakeven.

Do you think it was done so they were in total control and didn’t care about us?