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LONDON MARKET PRE-OPEN: FTSE 100 Set For All-Time Record At Open

Mon, 21st May 2018 07:40

LONDON (Alliance News) - The FTSE 100 is set to open at an all-time high on Monday, coming after trade tensions between the US and China eased over the weekend.In early UK company news on Monday, AstraZeneca said the US Food & Drug Administration has approved Lokelma, NewRiver REIT confirmed it is in talks to buy Hawthorn Leisure Holdings, and Ryanair reported a strong rise in annual profit but was cautious on its outlook for the year ahead.IG says futures indicate the FTSE 100 index of large-caps to open 41.01 points higher at 7,819.80 on Monday. The blue-chip index closed down 0.1%, or 9.18 points, at 7,778.79 on Friday. The index's current record intraday high stands at 7,792.56, a level which was reached in January of this year."The continued buoyancy in European markets is being helped in no small part by the weakness in both the euro and the pound against the US dollar, while concerns about an escalation in tensions between China and the US appear to have been deferred in the short term after progress in trade talks at the weekend," says CMC Markets chief market analyst Michael Hewson.In early UK company news on Monday, drugmaker AstraZeneca said the US FDS has approved Lokelma, formerly ZS-9, for the treatment of adults with hyperkalaemia.Hyperkalaemia is characterised by elevated potassium levels in the blood, associated with cardiovascular, renal and metabolic diseases. The FDA approval is supported by data from three double-blind, placebo-controlled trials and two open-label trials."We are pleased by today's FDA approval of Lokelma as it enables us to help address a long-standing clinical need with a new medicine that offers rapid and sustained treatment for adults with hyperkalaemia," said Sean Bohen, executive vice president, global medicines development and chief medical officer at AstraZeneca.Seperately, the blue-chip pharmaceutical firm said it has submitted a supplemental new drug application to Japan's Pharmaceuticals & Medical Devices Agency for the use of Forxiga - a selective sodium-glucose co-transporter 2 inhibitor - as an oral adjunct treatment to insulin in adults with type-1 diabetes.Forxiga is also under regulatory review in Europe.Noting press reports, FTSE 250-listed NewRiver REIT confirmed it has entered a period of exclusivity with pub company Hawthorn Leisure Holdings and its major shareholder regarding a potential acquisition of the business. "A transaction, if completed, would be funded from NewRiver's existing resources. There can be no certainty that a transaction will be concluded and a further announcement, as appropriate, will be made as soon as practicable," NewRiver said.Online gaming firm Playtech said it has received formal consent from the Italian gaming regulatory authority, Agenzia delle Dogane e dei Monopoli, for its purchase of a 70.6% stake in Snaitech.The deal, first announced in April, will see Playtech subsequently make a mandatory takeover offer for the remaining shares in Snaitech after buying its 70.6% stake.Budget airline Ryanair Holdings reported a 10% increase in annual profit after tax to EUR1.45 billion, saying that lower fares - which were down 3% - stimulated 9% traffic growth to over 130 million passengers. Full year 2018 total operating revenue from continuing operations rose 8% year-over-year to EUR7.15 billion. Traffic grew 9% with Germany, Italy and Spain being the company's largest growth markets.However, the airline said its outlook for the year ahead is "on the pessimistic side of cautious". The company expects to grow traffic by 7% to 139 million, at flat load factors of 95%. Unit costs in the current year will rise 9%.In addition, Ryanair said it has "limited" first half and "zero" second half fare visibility, with forward booking strong but pricing soft."Since only half of Easter fell in April, we expect a 5% fare decline in Q1 but a 4% rise in Q2 fares. While still too early to accurately forecast close-in summer bookings or H2 fares, we are cautiously guiding broadly flat average fares for FY19," Ryanair said.Elsewhere on the Main Market, 4D Pharma said the UK Medicines & Healthcare products Regulatory Agency has cleared a Clinical Trial Application for MRx0518, a live biotherapeutic cancer treatment. Enrolment in the Phase 1b study is expected to commence in the second half of 2018, 4D said."This groundbreaking study is set to be the world's first live biotherapeutic clinical trial in oncology and the first of a number of studies we have planned to investigate MRx0518 in multiple cancer settings," said Chief Executive Duncan PeytonIn the US on Friday, Wall Street ended mostly lower, with the Dow Jones Industrial Average ending flat, the S&P 500 down 0.3% and Nasdaq Composite closing 0.4% lower.Chinese Vice Premier Liu, who travelled to the US on Tuesday for negotiations, told Chinese news outlet Xinhua that both countries had agreed to "not to engage in a trade war" and "stop slapping tariffs against each other".He said that both countries had pledged to cooperate further in a "win-win choice" that would promote the "high-quality development of the Chinese economy".Liu's comments follow a joint statement released by the White House Saturday that China would begin buying more US goods and services to reduce the US trade deficit and meet Chinese consumption needs.Treasury Secretary Steven Mnuchin on Sunday said the US is "putting the trade war on hold" and won't impose tariffs for now while it works on a framework for trade with China. In Asia on Monday, the Japanese Nikkei 225 index closed up 0.3%. In China, the Shanghai Composite is up 0.8%, while the Hang Seng index in Hong Kong is up 0.9%.Released early Monday, Japan's trade surplus for April came in at JPY626.0 billion, or around USD5.6 billion, boosted by strong demand for Japanese cars and manufacturing equipment overseas.Exports were up 7.8% to JPY6.822 trillion, outpacing a 5.9% rise in imports to JPY6.196 trillion, according to a preliminary report by the Finance Ministry. By region, Japan saw its trade surplus against the US rising 4.7% to JPY615.7 billion thanks to a rise in car exports.In the UK on Monday, Rightmove said house prices were up 0.8% on month in May, which follows a 0.4% rise in April. On a yearly basis, house prices advanced 1.1%, slowing from 1.6% in the previous month.Meanwhile, a survey by IHS Markit and Ipsos Mori showed British households' current financial pressures softened in May, helped by a combination of lower inflation and higher income from employment this spring.The seasonally adjusted Household Finance Index, or HFI, rose to 44.7 in May from 43.4 in April. The figure signaled a softer budget squeeze, with the latest deterioration being the least marked since the end of 2016. However, any score below 50 suggests pessimism regarding finances among the UK households."Following the accurate prediction by the majority of households of no base rate change in May, the forecast has since remained broadly unchanged," Sam Teague, an economist at IHS Markit, said."Over half of all households are expecting a rate hike over the course of 2018, though only one-in four expect to see rates rise by August."To come in a thin economic events calendar on Monday there is the Chicago Fed National Activity Index at 1330 BST. Markets in Germany and Switzerland are closed for the Whit Monday holiday on Monday.
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15 Feb 2023 14:21

IN BRIEF: 4D Pharma shares cancelled from trading on London's AIM

4D Pharma PLC - Leeds-based pharmaceutical firm - Notes cancellation of its shares on AIM from Thursday, after it entered into administration in June 2022.

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3 Feb 2023 15:17

TRADING UPDATES: GCP Infra hails NAV rise; Jadestone profits from oil

(Alliance News) - The following is a round-up of updates by London-listed companies, issued on Thursday and not separately reported by Alliance News:

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9 Jan 2023 15:58

UK shareholder meetings calendar - next 7 days

Tuesday 10 January 
Valereum Blockchain PLCAGM
Wishbone Gold PLCAGM
Wednesday 11 January 
AB Dynamics PLCAGM
Asos PLCAGM
Edge Performance VCT PLCGM re deed of release
Hurricane Energy PLCAGM
Induction Healthcare Group PLCAGM
MetalNRG PLCGM requisitioned to remove chair and CEO from board
Synthomer PLCGM re sale of laminates business
Thursday 12 January 
JPMorgan Japanese Investment Trust PLCAGM
Friday 13 January 
eEnergy Group PLCGM re shareholder resolution to adopt the 2022 Accounts
Monday 16 January 
4D Pharma PLCGM re update on administration and suspension of trading
  
Copyright 2023 Alliance News Ltd. All Rights Reserved.

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30 Dec 2022 17:21

4D Pharma seeks approval for equity fundraise to lift suspension

(Alliance News) - 4D Pharma PLC on Friday said it was seeking shareholder approval for a USD15.0 million cash raise, as it works to lift its suspension and restore its shares to trading.

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16 Nov 2022 17:00

4D Pharma says trial results show Blautix eases IBS symptoms

(Alliance News) - 4D Pharma PLC said on Wednesday that its Blautix phase 2 clinical trial results showed the treatment had a positive effect on sufferers of irritable bowel syndrome

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24 Aug 2022 11:44

IN BRIEF: 4D Pharma publishes pre-clinical research for autism

4D Pharma PLC - Leeds, England-based pharmaceutical company - Releases its publication of pre-clinical research on mice regarding live biotherapeutic MRx0006 for the treatment of autism spectrum disorder. Says research shows LBP MRx0006 can attenuate core behavioural deficits in a mouse model of autism, improving social deficits, repetitive and anxiety-like behaviours. "Mechanistically, MRx0006 increased in the brains of ASD mice the expression of neuropeptide hormones known to regulate social and anxiety behaviour," 4D Pharma adds.

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5 Aug 2022 14:58

TRADING UPDATES: 4D Pharma warns of wind-up; Star Phoenix files claim

(Alliance News) - The following is a round-up of updates by London-listed companies, issued on Thursday and Wednesday and not separately reported by Alliance News:

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1 Jul 2022 20:05

TRADING UPDATES: Capital wins contracts; 4D pharma pauses enrolment

(Alliance News) - The following is a round-up of updates by London-listed companies, issued on Thursday and Friday and not separately reported by Alliance News:

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28 Jun 2022 21:23

IN BRIEF: 4D Pharma shares to be delisted from Nasdaq

4D Pharma PLC - Leeds, England-based pharmaceutical company - Says it has received written notice from the Nasdaq Stock Market that its securities will be delisted from Nasdaq. Accordingly, trading of its shares will be suspended from the opening of business on July 7. Nasdaq staff cited 4D's announcement that it had been placed into administration on Friday as raising "public interest concerns". The exchange also mentioned concerns regarding the residual equity interest of existing shareholders of listed securities.

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24 Jun 2022 19:09

IN BRIEF: 4d Pharma faces uncertain future as loan repayment due

4d Pharma PLC - Leeds, England-based pharmaceutical company - Says it has "no immediate certainty" of how it will repay the USD13.9 million loan facility it has with Oxford Finance LLC.

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24 Jun 2022 14:33

IN BRIEF: 4d Pharma suspends trading immediately, pending announcement

4d Pharma PLC - Leeds, England-based pharmaceutical company - Says it has ordered an immediate suspension of trading in the company's shares on AIM pending a further announcement.

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24 Jun 2022 12:35

4D Pharma requests immediate suspension of its shares

(Sharecast News) - Biotherapeutics developer 4D Pharma requested an immediate suspension of trading in its shares on Friday.

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21 Jun 2022 16:05

UK shareholder meetings calendar - next 7 days

Wednesday 22 June 
ASA International Group PLCAGM
Atalaya Mining PLCAGM
Bonhill Group PLCAGM
Chapel Down Group PLCAGM
Churchill China PLCAGM
Downing Renewables & Infrastructure Trust PLCGM re share issue
Ecofin US Renewables Infrastructure Trust PLCAGM
EJF Investments LtdAGM
Frenkel Topping Group PLCAGM
Good Energy Group PLCAGM
Honeycomb Investment Trust PLCAGM
ICG-Longbow Senior Secured UK Property Debt Investments LtdAGM
Intelligent Ultrasound Group PLCAGM
Iofina PLCAGM
John Wood Group PLCAGM
Kingfisher PLCAGM
LXi REIT PLCGM
Menhaden PLCAGM
North Atlantic Smaller Cos Investment Trust PLCAGM
Pennant International Group PLCAGM
Plant Health Care PLCAGM
Skillcast Group PLCAGM
Team PLCAGM
Tribal Group PLCGM re final dividend
Trident Royalties PLCAGM
Vertu Motors PLCAGM
Wentworth Resources PLCAGM
Thursday 23 June 
Avacta Group PLCAGM
Anglo Asian Mining PLCAGM
Card Factory PLCAGM
Cordiant Digital Infrastructure LtdAGM
Downing Renewables & Infrastructure Trust PLCGM re initial placing & open offer
Eight Capital Partners PLCGM re aligning 2022 bonds with 2026 bonds
GENinCode PLCAGM
Ideagen PLCGM re takeover by Hg Pooled Management Ltd
Longboat Energy PLCAGM
Oxford Nanopore Technologies PLCAGM
Puma VCT 13 PLCGM re cancellation of listing & liquidation
RBG Holdings PLCAGM
Tandem Group PLCAGM
Union Jack Oil PLCAGM
Zinnwald Lithium PLCAGM
Friday 24 June 
AFC Energy PLCGM re fees for non-executive directors
Avast PLCAGM
Devolver Digital IncAGM
Entain PLCAGM
Gulf Keystone Petroleum LtdAGM
Hawkwing PLCAGM
Invesco Bond Income Plus LtdAGM
Life Science REITAGM
Northcoders Group PLCAGM
Princess Private Equity Holding LtdAGM
Monday 27 June 
Anglo-Eastern Plantations PLCAGM
Celadon Pharmaceuticals PLCAGM
Cizzle Biotechnology Holdings PLCAGM
Echo Energy PLCAGM
Medica Group PLCAGM
Pelatro PLCAGM
Surgical Innovations Group PLCAGM
Warpaint London PLCAGM
Tuesday 28 June 
4D Pharma PLCAGM
Acceler8 Ventures PLCAGM
Airtel Africa PLCAGM
Alina Holdings PLCAGM
Aquila Energy Efficiency Trust PLCAGM
Attraqt Group PLCAGM
Bay Capital PLCAGM
Capital & Counties Properties PLCAGM
CMO Group PLCAGM
Corre Energy BVAGM
Creo Medical Group PLCAGM
Futura Medical PLCAGM
Gama Aviation PLCAGM
ICG Enterprise Trust PLCAGM
ImmuPharma PLCAGM
IQE PLCAGM
Katoro Gold PLCAGM
Rockhopper Exploration PLCAGM
Sound Energy PLCAGM
TP Group PLCAGM
UK Oil & Gas PLCAGM
Volvere PLCAGM
Zegona Communications PLCAGM
  
Copyright 2022 Alliance News Limited. All Rights Reserved.

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27 May 2022 10:46

4D Pharma reports progress in bladder cancer trial

(Sharecast News) - Live biotherapeutics developer 4D Pharma announced progress in the phase 2 clinical trial in bladder cancer on Friday.

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27 May 2022 09:31

IN BRIEF: 4D Pharma plans to test MRx0518 in combination with Bavencio

4D Pharma PLC - Leeds, England-based pharmaceutical company - Plans to conduct a phase II study to assess the safety of MRx0518 in combination with Bavencio. Says the study will be conducted in patients with unresectable locally advanced or metastatic urothelial carcinoma, a type of bladder cancer. Says previous data about MRx0518 supports the potential of this combination to "significantly enhance and improve" outcomes for patients, beyond treatment with Bavencio alone. Bavencio is an antibody medication for the treatment of urothelial carcinoma.

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