Director/PDMR Shareholding

GW Pharmaceuticals PLC ("GW Pharmaceuticals" or the "Company")

NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS

Porton Down, UK, 29 November 2010: GW Pharmaceuticals (AIM: GWP) hereby provides notification that the Company has today been notified of the following share transactions entered into by Mr Richard Forrest, non-executive Director and Dr Geoffrey Guy, a Director and Executive Chairman of the Company.

On 23rd November Mr Richard Forrest purchased 10,000 ordinary shares of 0.1p each from Dr Geoffrey Guy. This transaction between Directors, which equates to less than 0.01% of the issued ordinary share capital of the company, took place at the market price of 107.5 pence per share.

On the same day Dr Guy also transferred 8,420 ordinary shares of 0.1p each, equating to less than 0.01% of the issued ordinary share capital of the company, into his personal pension scheme. This transaction took place at the market price of 108.5 pence per share.

Following this notification:

Mr Forrest's holding in the shares of GW Pharmaceuticals plc has increased to 70,000 ordinary shares, amounting to 0.05% of shares in issue.

Dr Guy retains a beneficial interest in 18,354,448 ordinary shares, amounting to 14.0% of the shares in issue.

The total number of shares outstanding in the Company is 131,228,292 ordinary shares of 0.1p each.

For further information, please contact:

GW Pharmaceuticals PLC +44 (0)1980 557 000

Adam George, Company Secretary

Piper Jaffray Ltd (Nominated Adviser)

Neil Mackison/Rupert Winckler +44 (0) 203 142 8700