BLOCK LISTING SIX MONTHLY RETURN

Name of applicant:

Circassia Pharmaceuticals plc

Name of scheme:

Circassia EMI Share Option Scheme

Period of return:

From:

1st January 2016

To:

30th June 2016

Balance of unallotted securities under scheme(s) from previous return:

1,236,125

Plus: The amount by which the block scheme(s) has been increased since the date of the last return (if any increase has been applied for):

-

Less: Number of securities issued/allotted under scheme(s) during period (see LR3.5.7G):

-

Equals: Balance under scheme(s) not yet issued/allotted at end of period:

1,236,125

Name of contact:

Julien Cotta

Telephone number of contact:

01865 405 560