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https://www.lse.co.uk/rns/GSK/gsk-and-iteos-announce-collaboration-for-eos-448-h1jspx85t9s8d6b.html

*GSK and iTeos Therapeutics announce development and commercialisation collaboration for EOS-448, an anti-TIGIT monoclonal antibody, enabling novel next-generation immuno-oncology combinations



· EOS-448 is currently in phase I for advanced solid tumours with a randomised PD-1 combination study planned for 2022

· iTeos to receive a $625 million upfront payment in addition to potential milestones, and royalty payments on ex-US sales

· GSK and iTeos will co-commercialise and share profits in the US

· GSK now has the leading portfolio of antibodies targeting the CD226 axis - a key target for next-generation immuno-oncology therapies"

Not sure how this compares to Scancells equivalent (or if comparable?), but just goes to how show how much money is swishing about for 1x mab!? What's Scancell/Scancells equivalents worth?

Another great summary crumbs.

But it all just makes me wonder, something I (and maybe others?) have mentioned before, all those news strands and not a peep for several months? Something doesn't add up for me. Purely IMO, it feels like they holding it back for one or two major annoucements relating to a tie up with a prefect partner i.e. a BioNTech. Just seems like lots (and lots) of t's being crossed and i's being dotted to me? But as mentioned this is just purley (hopeful?) conjecture.

And I think with Covidity there will be pharma tie up news sooner than we expect. Plus the simple fact the variants aren't going anywhere anytime soon.

Not sure if these were there before, they but don't ring a bell, but both quite interesting and both large market cap. esp Legend
Because not everyone has access to twitter it seems, they are:
Zai Lab Limited (ZLAB) - http://www.zailaboratory.com/
Legend Biotech - https://www.legendbiotech.com/

I wonder if this explains the extra bounce to the SP? Whilst a good reaction was expected after the Diggle Wiggle, i think today in particular was a bit surprising, to me anyway. Either way something is afoot IMO!
P.s. The Scancell workforce/science team must be getting quite large now!?

Yes great find cc24601! Very promising indeed.
Also interesting that the closing date for the roles is just over three weeks time for all three roles? Not very long IMO.

Spot any subtle changes WF?

For less than 20k shares atm, anyone else?

"It is natural that our minds ponder the reason for such quiet."

This is the key point, boredom and frustration has taken over a little, I can confess it has for me anyway.

We need something else to talk about...like an update or an RNS perhaps! Hell, I'd take a retweet atm!

Edit - still see*
But in the context of Scancell, they've put a huge onus on generating the data first when big bios are clearly ok with not having the data when it comes to some M&A? What makes Scancell so special/different? Why would big bio not also try and jump the gun here? Are the products too novel?

RE data, something I never understood is why we see humongous deals for pre-clinical data bios/products?

@krafty, I was thinking along the same lines, keep wondering why we've not had an update on any of the many, many ongoing strands, surely at least one is overdue an update? So is there a possibility of an deal that is much more all encompassing than most expect? Hence the radio silence?

Agree Billbrown, it is encouraging, also perhaps slightly unrelated there was a 400k approx two weeks ago(?) which went unreported.

So appears there's some demand to buy at these bargain basement prices?

IMO if crackin's posting his usual doom laden prophetic price predictions it's usually a good sign to top up* (another bear trap perhaps?)

Bang on cue Crackin lol.

...edit...just to add... Looking at it from a more positive angle hopefully the impending news is going to be huge...hence the wait!

Yes Violindog, I agree this news blackout is extensive in the extreme IMO and yes seems unfair on shareholders esp LTH's. Simple small updates just here and there would make a huge difference mainly in terms of peace and mind for us and to the SP (although I see all the dips as buying opportunities atm, but that is beside the point). All IMO.

So is that part of the same CEPI call? I.e. are they announcing them now?

"Knowlessi, you should be a politician. The share price hasn’t been ‘falling for weeks’. It has been consolidating for weeks and has been remarkably steady for an aim stock while waiting for news."

But hey don't let facts get in the way hey Knowelsi :) But I suppose you are the all knowing oracle after all.

@Konar, agree with you there totoally, thats' potentially three bits of news/updates now that they could have given to us shareholders. Lots of other companies would have at least provided some kind of update, unofficial or not, even if it's just on the website. Realy poor showing IMO.

Part of me is thinking they are keeping quiet on purpose so directors and/or friends of the board can load up whilst price is surpressed/ranging.