Member Info for tomvisual

Tex2374, low free float is an added bonus for shareholders! Thanks.
Test, test, test

BRH also have an investment (52%) in an antiviral face mask Company, Pharm2Farm Limited (P2F).
Guardian has an interesting article on face masks!

https://www.theguardian.com/world/2020/oct/02/the-most-common-ways-were-wearing-face-masks-incorrectly

PL75, Shear class so x4 from here potential!
Now TTP (who helped with ventilator programme) are after a 5 Minute test.
https://www.ttp.com/news/douglas-bradshaw-talks-to-bbc-radio-4s-today-programme
Why? To help the national effort. Furthermore, Govt spent £292million excluding VAT on its ventilation programme
https://www.dailymail.co.uk/news/article-8787707/Thousands-ventilators-bought-height-Covid-crisis-sitting-warehouses.html
If TTP get involved, see my earlier post, what market cap do you think this can grow BRH to?
There is a lot of money available for good covid tests.
No one Company has a monopoly -Dr AS (CEO of Avacta) told Avacta shareholders!!
UKs Govt shambolic, that is, non EXCELling performance, has made the situation more acute.
Step forward a 5 Minute rapid covid test from Paraytec/Sheffield University (100% owned by BRH)!
Planetary alignment to me which does not need a telescope!!
Can the tortoise win the race?
It just needs to participate for shareholders here!
Full POC validation 16th October!
No brainer investment for me.
GLA.
Test, test, test

30% gain to Zak's first target.
My target is higher, but other intermediate targets need to be reached first.
DYOR. Look at the market cap here compared with other covid stocks. Calculate what share price equates to this comparable market cap!
Even half of your estimate is substantial from here. No need to ramp, do the calculations!
GLA.
As the POC has been derisked for me when the new Paraytec detector was used:
https://twitter.com/carlsmythe/status/1313056511988465664
Onwards and Upwards.
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Zak Mir, BBH first target looks like 52p!
https://www.share-talk.com/share-talk-bulletin-board-heroes-wednesday-30th-september-2020/#gs.hfu47n

No doubt this will be updated later this week!
Today??
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Noted.
More than happy with a 5 Minute Covid Test.
Test, test, test

The objective for Paraytec/Sheffield University is "to develop a portable test, which can generate a result in a matter of minutes provided at the test location and which requires no specialist skills for its operation"
90 second test is an massive advantage.

For a pregnancy type test, you need a Lateral Flow Test (LFT). You need to look at Avacta. They should have a LFT test within 3 months.
Dr AS (Dr Alistair Smith, CEO of Avacta) has stated that Avacta do NOT have the capacity to deliver all covid tests. Hence, every Company producing MHRA approved tests will be rewarded.
Speed is key for my investment here at BRH.
Market cap of BRH (<£13M) for a rapid 90 second covid test makes this share a no brainer!
DYOR, the POC by Paraytec/Sheffield University seems to be massively derisked to me.
Final proof of POC by Oct 16th.
GLA
Test, test, test

Isthisawinner, the synthetic chimaeric protein used by Paraytec is an aptamer. Antigen tests do not have the same issue when compared to PCR. This is an important consideration, as the response is more tightly defined. For time from symptom onset variation between the covid test assays (PCR Vs Antigen Vs Antibody), see the graphical figure
"Fast coronavirus tests: what they can and can’t do":
https://www.nature.com/articles/d41586-020-02661-2#ref-CR1

The use of an aptamer reduces the likelihood of false positives after individuals are no longer infectious.

Speed of test is the key. That's why a 90 Second test is very important here!
Test, test, test

Nothing to Excel About, Daily Mail reporting:
An epidemic of failure:
Test and Trace that doesn't work,
local lockdowns that don't make sense,
flu deaths counted as Covid-19...
and an economy on the brink.

We somehow made a crisis worse
https://www.dailymail.co.uk/debate/article-8808609/DR-JOHN-LEE-Test-Trace-doesnt-work-local-lockdowns-dont-make-sense.html

Basic IT blunder exposes flaws in coronavirus test-and-trace service that was cobbled together at speed.
WE ARE IN TROUBLE!
The UK needs to throw everything at mass testing to isolate infectious individuals.Multi-pronged approach is required...
High frequency, Fast testing is necessary.
Test sensitivity is secondary to frequency and turnaround time for COVID-19 surveillance.
https://www.medrxiv.org/content/10.1101/2020.06.22.20136309v3
Rapid acceleration of promising tests required by UK Government. £100B war chest was mentioned as Project Moonshot. Lets get investing this money otherwise another national lockdown looms.
A rapid 90 SECOND test is potentally available here! UK Manufacturing effort needs to be galvanised!
Nothing fitted the bill, perhaps until now!!

Sorry, rant ended.
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The objective of the project is to develop a portable test. This is what makes this investment exciting!
Market cap of <£13M for a 90 second covid 19 test with POC nearly validated!! (No need to ramp!)
From: https://www.londonstockexchange.com/news-article/BRH/final-results/14639862

The Company (Paraytec) has commenced a programme with University of Sheffield to develop a rapid test for the pandemic pathogen, COVID-19. The test involves the deployment of a DNA aptamer - a short, single-stranded DNA molecule that adopts a shape that is complementary to that of the virus surface protein. By coating a test surface with millions of copies of the aptamer molecule, our capture module can trap Covid-19 virus particles from a swab sample, as they flow over the test surface. Trapped viruses are then instantaneously coated with the signal generation module, a synthetic chimaeric protein, that both recognises the viral surface as well as being highly fluorescent. The resultant fluorescent signal is measured by the detection module using a version of Paraytec's patented Actipix area imaging technology configured for fluorescence detection.
In this project, Paraytec is working with Professor Carl Smythe's group at the University of Sheffield - which has expertise in the field of synthetic bio-molecular sensors. Formerly Academic Director of the Sheffield Cancer Centre, Prof Smythe's research is focused on cellular quality control systems monitoring chromosomal DNA. With 35 years' research experience, he has, together with collaborators in academia and industry, developed a wide range of sensor systems with applications in disease testing.
The objective of the project is to develop a portable test, which can generate a result in a matter of minutes from a swab provided at the test location and which requires no specialist skills for its operation. If successful, it could be used in airports, transport hubs, large workplaces and similar settings, where rapid screening of large numbers of people for presence of COVID-19 or any future emerging pandemic is required.
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Goldballs, I am happy with 90 to 120 seconds.
The next important stage is as you mentioned finalising the POC by 16th October.
As HaHa said this could be a major fast test to add to the UK Govt test arsenal!
Test, test, test

Looking at Carl Smythe's Twitter post of the output of the Paraytec detector there is a first indication after 20 secs.
https://mobile.twitter.com/carlsmythe/status/1313062839515574272
A question would be: how many of those spikes do you have to have to declare a positive result?
Do we have a 30-90SECOND test here???
Test, test, test

Looking at Carl Smythe's Twitter post of the output of the Paraytec detector there is a first indication after 20 secs.
https://twitter.com/carlsmythe/status/1313056511988465664
A question would be: how many of those spikes do you have to have to declare a positive result?
Do we have a 30-90SECOND test here???
Test, test, test

90 second covid test!
Market cap <£14M (share price 38p).
Proof of Concept derisked!
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Rocky500, can you elaborate?

Paraytec/Sheffield University's 90 SECOND test aim for good Sensitivity is a possible advantage over other 5 to 90 Minute tests!
Interested to known your technical opinion here!
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My investment here has just got very interesting!!
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There was a More or Less podcast, 'The Magical Maths of Pooled Testing' , where the Israeli algorithm featured.
Also see (30/9/20 broadcast):
https://www.bbc.co.uk/sounds/play/m000mywc

What a good idea - the maths, as one could well imagine, gets complicated when there are false positives and false negatives.
I hope that the algorithm is being worked on or even trialled in the UK, but that has not got into the news.
A 2 MINUTE test method opens up the possibility of MASS TESTING!!

Reference https://www.poold-diagnostics.com/
which takes you to the Web site of the Israeli researchers (referenced by MoreorLess) with links to the papers.
If prevalence is less than 8%, a 2 MINUTE test coupled with pooled test algorithms is a GAME CHANGER for MASS Testing.
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PL75, and DrAS told us no one company has the capacity to supply all the covid tests needed!

The best tests in terms of speed (2 Minutes -BRH?), Sensitivity and Specificity will rise to the top of the covid stocks.
Paraytec's/Sheffield University test methodology. aim for good Sensitivity is great advantage here.
R4 More Or Less podcast on pooled tests, that would be one application where the, hoped for, good Sensitivity of Paraytec's /Sheffield University test is required. This makes them both complimentary as opposed to exclusive!
IF this assumption is correct, this would be excellent for share growth for BRH.
Test,test,test

PL75, welcome aboard!
Will need a bigger boat here!!
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2 Minute Covid Test???
No viral protein present
https://mobile.twitter.com/carlsmythe/status/1313056871721373698/photo/1

Viral protein present
https://mobile.twitter.com/carlsmythe/status/1313056511988465664/photo/1

Night and day comparison!
Well done Paraytec/ Sheffield University

Test, test, test