Member Info for ThinShins

Maybe a daft question but I'll ask anyway, would regulatory bodies such as MHRA/FDA/EMA take into consideration research from independent sources when making decisions to further progress the trials?

For anyone who is interested and not viewed last years September panel including RM - "Therapeutic Strategies to Prevent & Treat Covid 19 Panel"

https://youtu.be/IOHmVnttowM

home trial started approx June 2020 right? should it really take this long for a trial with just 120 patients.

His talk was from a month ago, its being made available for public viewing tomorrow. However even if from a month ago he will hopefully be dropping a lot of hints as to what is coming up in the pipeline.

@F&V, you can try right clicking on the image and "open image in new tab". You should then be able to zoom in/out

Mr Joe, RM has already given his talk on the 9th of March the video is due to be published on YouTube on the 8th of April.

https://youtu.be/-6UUKBD62gk

Home Trial results due in Q2 (April, May, June)

Does anyone realistically think we will get results May or June?

Mr Jaffjoon, once again congrats. I came across a name today that I dont see too often and I remembered this post.

I dont wanta throw a spanner in works if you and your partner have already settled on a name but Shanae-Jen would work great for what you have in mind.

Best of luck

totally agree Mr Woodstock, people on this forum are actually encouraging others to keep "light pressure" on the company by emailing them, they are probably already working themselves thin and a bombardment of emails from PI in to their inbox surely will not help help anyone more so a hindrance.

Just pointing out something Iv noticed, since last March 2020 up to February 2021 we have had some form of an RNS from the company consistently at least once a month, so far we have had no RNS/TR1 for March, the SP for this stocks is mainly driven by news, lack of news will result in a likely drop in the SP which we are experiencing. Hold tight Synners you dont wanta be left smelling the smoke once news does arrive.

@theboyg - if results are "not good" they would have been booted out of ACTIV-2 trials by now like other candidates have. The evidence in regards to interferon as a immunomodulator / antiviral is piling up fast. Previous trails and data sets are very encouraging and I'm confident we will see great results in all trials we are in. In terms of when we will see results we have to stick to the timeline that has been given which is - results for HT in Q2 for HT. Yes we all hope for sooner results but if you are banking on that you are just setting yourself up to be disappointed.

Org/Aston, I wont lie and say it would be sad to see you go but I for one will be glad to hopefully see this board get to a consistent level of good discussion and research sharing. I personally have no issues with you posting as I simply just read and move on if i don't agree with you BUT you are one of the most controversial posters on here which leads to this board just becoming congested with back and forth bickering.

You seem like a friendly nice chap, wish you all the best in your future endeavors.

Thrusters due to be engaged? ??

Thanks Ghia!

Regardless this is still positive news, it will be interesting to see how this plays out seeing as most care home residents should have had at least 1 dose if vaccine by now, even if a CH resident does contract covid what will they be comparing their data with? Who will be the control group? vaccinated+placebo vs vaccinated+SNG001 im guessing?

"The trial will begin in May 2021 and last around 2 years"

Struggling to see why SNG is needed in this, we already have peer-reviewed data on our hospital arm and soon we will have data on our home arm. The cohort in our running trials is over 65s and over 50s with comorbidity totaling to over 200 patients. so it doesn't differ greatly from patients in a care home setting. Data from these trials surely enough to make a decision on safety and efficacy. Is a 2 year trial really needed?

Can someone shed some light as to the significance of this trail if we are in fact included.?

@hewhodares1 just some info in relation to a link between CBD and interferon.

https://www.news-medical.net/amp/news/20210314/Cannabis-compound-inhibits-SARS-CoV-2-replication-in-human-lung-cells.aspx

"The CBD inhibited viral gene expression and reversed many of the effects the virus has on host gene transcription. The compound also induced the expression of interferons – cell signaling proteins that are produced by host cells as an early response to viral invasion."

https://www.news-medical.net/amp/news/20210314/Cannabis-compound-inhibits-SARS-CoV-2-replication-in-human-lung-cells.aspx

"The CBD inhibited viral gene expression and reversed many of the effects the virus has on host gene transcription. The compound also induced the expression of interferons – cell signaling proteins that are produced by host cells as an early response to viral invasion."

J_CIT,he EU have been shooting themselves in the feet on multiple occasions, their lackluster vaccine rollout is their own doing. Late contracts, late approvals, senior officials making unhelpful remarks about AZ being "Quasi-ineffective", member states not approving for certain age groups, AZ vaccine targeted as health risk when Pfizer has had similar amount of blood clot cases.

All the above will result in a slow roll-out with many EU citizens probably not comfortable taking the Ox/Az and now threaten to cut legal contractual exports for a vaccine to countries who have a successful rollout.

Was the question by the Newcastle MP answered in regards to pre-orders of SNG001? I remeber reasing answer was due for 1st of March lol. Cant recall the MPs name, if anyone does know can they check please?