Member Info for ThinShins

8:06 AM this guy was already predicting a red day hahaha green bin for you sir

Long covid update

Firstly what a fantastic rise we've had today, confirmation that SNG001 is effective against variants. Even though many of us knew this would be the case its great to have some scientific evidence to back it up and with variants being a hot topic at the moment.

This totally slipped my mind and probably caught many of us off guard, I was just wondering when do we expect to have an update on long covid for our trial participants, I recall RM saying we would be updated about this when the data is ready. Another one to keep an eye out for.

GLA

BOOM!

Xviolet

Fingers and toes crossed for a Monday RNS in regards to ACTIV2 progression!

Isn't this an Australian Radio station?

"About us: HPR is an internet only radio network that has been broadcasting globally with dedicated audio streams for Brisbane Sydney and Melbourne over the internet now for 2 years. It targets health professionals in hospital based environments but does not exclude other health professionals or the public from listening.."

"Given the Activ-2 entry criteria are wider, at least for the current P2, the hospitalisation rate may well be lower than for our home trial. "

I agree but this is a hurdle for all the treatments currently going through p2 of ACTIV2. A bonus we have is that we have supporting data on 120 patients from our SG016 home arm so in total they will have data on 340 patients who trialled the drug in a home setting. 220 in A2 and 120 in SG016. Hospitalisation rate will be low as most would have recovered on their own but this is something the brainboxes will factor in surely.

Hoping for progression to p3 with and adapted protocol targeting a more specific cohort such as the breathless .

Geo, we are being trialled in ACTIV-2 (outpatient treatments) and currently in phase 2, hopefully we will progress to phase 3.

ACTIV-3 is for inpatient treatments, which we are not participating.

GLA

https://www.youtube.com/watch?v=QSvh_n1iaM8

SP would be nice, but would have thought with approvals in place in markets such as US/UK, the SP would be quite higher than £2. That would be disappointing. Hopefully we have long awaited ACTIV-2 update which should hopefully shift market sentiment and put as back on a good trajectory to around SP of 1.75 .

Tony - with approvals in UK and US you are predicting the SP will be around £2?

scrap that close of 104.2

-_-

We had nice a lil rally like this last week Thursday pre RNS.

Active-2 update tomorrow, possibly?

MrCosts, unfortunately for us RM seems to have a policy where he will only update investors on what he is legally obliged to. My personal opinion is similar to yours, more updates via twitter or other platform would protect the SP and reassure us PIs and the wider market that things are progressing.

If A2 goes well and progresses and we get EUA in the states, would this mean that SNG001 can only be used in the setting it was trialled in? With EUA could SNG001 be administered to hospitalised patients or would further trials need to happen for use on hospitalised patients?

Ghia, that I can agree on. Apologies to anyone Iv been a bit ratty with the SP drop on Friday combined with currently having covid has me on edge. Best of luck to all.

Ghia, Iv prob read the same article you have, these people likely let their guard down with a false sense of security and were either infected soon before or after their first dose. That’s no knock on the vaccine, that’s just people being careless or unfortunate enough to catch the virus soon after their jab. I agree that yes the vaccines were designed to protect from the original wild virus originating from wuhan and yes a booster is likely with uk suggesting they hope a booster is available for autumn.

Difference is that take up on flu vaccines is very poor compared to what the demand is for Cov19 vaccines

Schrow, seems like you wanta believe the science when it comes to SNG but not vaccines. All evidence so far shows the vaccines are highly effective in protecting from hospitalisations and this where our drug is most effective, what you are claiming is equally a myth untill proven otherwise.

Oh cool what is it a treatment for then? from what I can see all our current trials are to treat sars-cov2 which is a virus.