Member Info for Sangijuelas1

I am researching Mirati Therapeutics at the moment and dipping toe. Kras inhibitor in for FDA fast track approval

Thanks for alerting me to this researcher

:)

Thanks Richie. I will definitely take another look here if they can get funding sorted.

They may still conjure up some data on the NSCLC cohort in the meantime.

I didn't exit due to a lack of patience.

I exited due to the uncertainty around funding.

I see John Doyle was skirting the line between truth and fiction yesterday.

Saying that they had drawn down $12.5m from Oxford when the actual funding that was unconditionally made available was only $5m.

Red flag for me

I think the idea with drones is to improve on delivery times in local area, fairly dense suburban areas ideal.

Getting them to be viable is seen as an important goal for retailers and also governments that want to reduce road traffic.

At the moment they can only work for shoebox size parcels - so delivering coffee, medicines, ice cream quickly

Baillie Gifford emphasise the need to find investments that solve real world problems.

If they get the technology right no doubt applications will be found that haven't even been thought of yet.

Was just reading about drone delivery as Walmart have just extended their US pilot.

Wonder what the future holds for Manna. Google are running a pilot as well.

Manna and others are able to learn from Amazons mistakes here as they wanted to land the drone but it works better lowering package on a chord.

Tesco working on Mannas Irish pilot

A lot of the current volatility is based on relatively low volumes - that recent 5% in a day Nasdaq drop was barely above normal daily volume

Seems to be a bit of a buyers holiday.

I mean yeah they may crash further but not because people are telling you they will.

At the end of the day you find a company you like and you own it even if the market was to shut down for 10 years

The general consensus is that tech stocks still have a lot further to fall.

I don't think it will otherwise it wouldn't be the general consensus.

Freetrade have a Sipp and an ISA and some suggest their flat fees are better for larger pot. I believe they have recently hailed increased use by Silver Swipers.

Obviously a platform should be chosen with a great deal of care in terms of suitability for ones needs. IFAs have to produce a suitability report for clients if they ever want to move assets from one platform to another.

I haven't investigated Freetrades functionality. I just use them for a GIA, which does everything I need for trades as opposed to longer term investments, which are on AJ Bell.

I don't want much from a platform other than to get trades executed on as broad a range of assets as possible and that they are financially stable.

My comment about advisers and AJ Bell referred to the fact that most of the assets on their platform are from clients of IFAs, who can easily take over if a client wants them to. HL opted to ignore the adviser market.

It was them that said they need to increase investment in their app and platform. It could be that it works fine but is a bit creaky due to age. I believe they struggle to deal with much higher market volumes than the daily average like when they announced the vaccine news.

I just wouldn't invest in them even though they have had a big drop. I would in Ocado at the current price.

Just using HL as an example of a company that focused on profit at the expense of ongoing investment.

You know we have had companies like Hargreaves Landown. Quickly became profitable but now is down 50% and has had to suspend their special dividend.

Because they now realise that they didn't invest and so are now having to rush to do so.

Yes they can invest from their profits but perhaps they will have lost ground against future threats from the likes of Freetrade.

I cannot really understand why anyone under a certain age would use them. They add no value to an investor other than having a name that might appeal to a certain type of person and they seem very expensive.

I think sadly they will start to lose their customer base over time, sadly from much of their customer base ageing. And some will look to use a financial adviser, which HL don't even cater for unlike AJ Bell.

As for Dodl it goes to show the superiority of the Freetrade offering in terms of range of investing options.

I mean maybe launching the app in France could turn out to be a smart move.

People say Europeans aren't into investing so not worth entering the market. Well maybe that's a lazy assumption and they just need better tools to trade. Young French people are certainly big fans of crypto

I feel GROW has the potential to play an important role in discovering and helping develop European tech champions.

And let's face it, they are desperately needed and European politicians get this. I would go so far as to say even Jeremy Corbyn recognised this with a manifesto commitment to manage the transition to automation.

The US has led the way with Japan, South Korea and now China.
A Tesla car, a Huawei phone, Amazon cloud, Salesforce software, You Tube videos, Apple gadgets, Fanuc robots, Nvidia chips, Netflix entertainment, Moderna and Pfizer RNA vaccines (yeah BioNTech but Pfizer funded), SpaceX rockets.

If it had been left to Europe none of this would have got off the ground. Either through under developed capital markets or over developed ones where all that remains is to suck out every last penny in dividends for as long as possible.

So we can all sit with our cynicism and scoff at how overvalued and overfunded tech companies are and enjoy the show as they face funding troubles and fail to deliver on their grand promises.

Maybe one reason why some don't quickly turn a profit is because they are building and defining a market, thinking about the sustainability of scalable returns and seeking to capture all the opportunities that exist.

Times like this can also be beneficial for VC funded companies as their partners can adopt a tougher approach. Google was given a kick up the arse by their investors, which prompted them to start looking at how they could start using their data on user searches to make products for advertisers.

So I think you have to be in it to win it and it takes time to build a business. There's a reason why "value" stocks were lagging the tech stocks for so long and that is because some of these businesses will fall by the wayside due to disruption.

Bailey is not a man to inspire confidence.

Apparently there are Tories that want to abandon independence for the bank and bring it back in house

No Snake, you never make an explicit claim.

You just rumour monger hinting that you have privileged info.

I thought I had you filtered.

Hadn't posted before as assumed had been seen

Was oversubscribed

https://www.google.com/amp/s/techcrunch.com/2022/05/17/earlybird-vc-closes-new-e350m-fund-for-western-european-startups-with-a-deeptech-angle/amp/

Conflicting reports then on Revolut. Bloomberg said 2 weeks ago they expect another round at a higher valuation. Storonsky said they are profitable a few days ago and won't raise again until they list.

As for Graphcore if they do raise at a lower valuation then so be it.

I would be more concerned if I was hoping for a quick return rather than looking for a patient capital type return.

Is it at the Amex in Brighton?

:)

Always got to look under the bonnet with any portfolio.

I also added a few at 528 last week. I almost want it to drop lower but I probably have enough.

Ocado have recently unveiled a new framework for the robots- much lighter, more energy efficient and can be built quickly from 3D printed parts.

They won't suffer from staff shortages through illness or union organising like is happening with Amazon, demands for higher pay due to inflation.

The UK business is primarily a showroom for their technology to enable sales to other supermarket customers, although I believe they are exceeding the targets from the M&S partnership.

I can't see picking by humans being a sustainable solution. It already seems to have been effectively dispensed with by the major supermarkets.

Maybe one way to look at what Ocado is doing is to consider early car makers. The technology is developing and there will be setbacks or lean periods. I imagine the pandemic upheaval was probably not the best time for businesses to consider wholesale change.