Member Info for Nolupus

Frightening reaction on this BB !!

I personally would prefer that a vaccine be discovered and the quicker the better for mankind even if it costs me a few grand in my portfolio ...
My parents and my children are worth more than money to me but it seems that everyone is not of the same opinion ..

Shpunken,

Things are going much faster than you think !
Pfizer are setting the timeline for late this year ....

https://www.forbes.com/sites/lisettevoytko/2020/05/05/pfizer-launches-us-human-trial-of-coronavirus-vaccine/amp/

Moving quite quickly ...

Here is a website which shows what's going on... for those interested

https://vac-lshtm.shinyapps.io/ncov_vaccine_landscape/

Ghia,

Exactly, the trial is designed to exclude people who are already in the ´cytokine storm by excluded all patients already in ICU.....

Ghia,

Whilst everyone is saying that Lansdowne are in troubled times , I am just pointing out that they were already in ´troubled times when they invested in the placement shares.
Looking in the rear view mirror is easy as some would love to buy in now at 35p but the SP could just as well have gone down after the placement :-). So risk management must have had some say in the matter when they were subscribing during ´troubled times ´ imv

Notnow20,

Can you remind us when Lansdowne invested in the placement shares, please ?

Their situation has'nt changed that much since then, has it ?

Thanks Ghia,

It's for the good of the board and not just for me :-)

Guys,

They knew their situation when they invested their money in the share placement not so long ago ...
Whatever their reasons, all we can do is speculate and only they have the answers.

Ghia,

Thanks , very helpful ....

Btw standard of care may vary from one hospital to another ....so Southampton is the key ....

You will also have noticed îam sure the
Exclusion criteria for this trial :-)

If not well worth the reading :-)

Ghia,

When patients are in hospitals , they get standard of care drugs to treat them ....
The clinical trial involves giving people the ´ active molecule ´ on top of these treatments or the ´placebo ´

Ghia,
A question I would like answered is what are the standard of care drugs that are being administered in the Southampton and other hospitals for covid patients ?

We must remember that these drugs are our placebo in the clinical trial ...

All patients will be taking them even those getting SNG001 so it's very important to identify them, imv

Interesting reading

https://www.bergenbio.com/ceo-letter-covid-19-clinical-trial/

Ghia,

As you rightly pointed out , I do just that..
I give a contrarien Point of view , which everyone is free to agree or disagree with .
It leads to debate and research and hopefully a more balanced viewpoint from most of the participants, imv
Even Miggy has changed his tune and become more factual when he posts his alpha and beta ..:-)

Everyone to their own views and trades is my motto and we are all learning every day

Oilornothing,

It's very easy to understand really :-)

Our objectivity is hindered by our investment blinkers :-)
We only want to hear and see POSITIVES when we are invested , and the more we are invested , the more we don't want to be objective , imv
SNG has POTENTIAL and therefore we should see just that...and not transform Potential into FACT which people have a tendancy to do when they are over invested .
I may be ignored or maybe filtered ...or even the brunt of cynical and insulting comments , that's what happens on these boards if you don't ´fit in ´
Si be it ....

AstraZeneca has spent hundreds of millions on ANIFROLUMAB , a monoclonal antibody targeting the OVER expression of interferon alpha and beta , in the last couple of years .
During this same period , they gave back the rights to SNG .

fact

The nasal drops were interferon alpha and not interferon beta .....

Totally different

In th US clinical trial WEBSITE :-)

Ok

People will say I am deramping ´ again ´ pff

But something is not right in these updates .....

In the Us clinical trial either it took an amazing amount of time to get online and therefore we can expect modifications or
Not....

I would like Richard to please inform us if this is one trial of a new estimated trial of +/- 400 patients recruited VIal hospitals and home trial with a readout estimated at late august or
Two seperate trials with two seperate readouts
1 in June and the other in august !!

I would like that to be confirmed by management asap ...

Things move fast but we need to know what's changing

The date of the 31/08. Is given by the company and is an estimate only ....

Lot's of information on here, I had'nt réalisés that they getting patients from Belfast ?

All clinical trials are required to register on this clinical trial register ...
I was surprised that our trial was'nt already featured here but now it's done

People should note the estimated primary completion date of the 31/08/2020