Gordon Stein, CFO of CleanTech Lithium, explains why CTL acquired the 23 Laguna Verde licenses. Watch the video here.
I can understand that D, my mother said she would refuse chemo if ever diagnosed with cancer after watching my sister die. The chemo side effects were the worst suffering.
Ava6000 and the platform as a whole will be truly revolutionary.
Thanks M, yes it is BRAC1. My friend is hardcore, extreme athlete , completed numerous Iron Man triathlons, yet chemo broke her. Both physically and more so psychologically . She did her first run today since summer and it has given her hope.
That article is fascinating, I will send it to her. Her father is Scottish. Thanks for sharing it.
I was thinking of you Mowzerrocks this morning, wondering how you are? My closest friend has just finished her chemo after ovarian cancer and major surgery to remove it, she will have double mastectomy in couple months. It’s been horrendous for her. She will survive though unlike my sister who had all the awful side effects with no comfort of a recovery. It will be like changing for cancer sufferers to have chemo without the awful side effects.
I wish you well mowzerrocks. The last chemo is a particularly emotional one besides all the awful side effects. This is such a difficult time for you and yours. I hope the radiotherapy goes well. Let us know how you are getting on.
I agree ES. On the science day video during the panel talk Tap says that targeting the tumour micro environment is a breakthrough and you then have a whole new field of therapy. He says they are not far from that.
At 2hours 39 Minutes when Fiona describes her perfect example of targeted therapy she gives AS a knowing glance when she speaks about translocation and inflammation and small molecules or scaffold that you can express in a cell that will inhibit inflammation.
This break through won’t just treat cancer, they will be able to target many other diseases.
I’m so excited to be on this journey with the company. The science is incredible.
Doxorubicin (DOX) is a highly effective anticancer drug with a broad spectrum of activity. It’s a powerful cytotoxic and there is great potential in larger doses with the reduced side effects. I think it is prudent not to underestimate the difference AVA6000 will make when FAP+ tumours are targeted early on with higher doses of dox. The cytotoxic effect on the tumour may result in shrinkage that allows surgery and therefore offering the patient a cure.
When my sister was diagnosed with liver cancer at 41 years of age, they gave her six weeks to live. She had four children under ten years and wanted desperately to live as long as possible. The doctors were astonished that after 4 doses of Dox her tumour had reduced by 2 cm, they said 1 cm more and they could operate to remove the tumour. The dox was working but her cancer had spread. She lived 8 months and we would have given anything to have her longer. Every day was a day her children had their mummy. I am certain had she been able to have a higher dose of Dox intially , they could have then operated and removed her tumour.
The side effects of chemo made her distraught.
AVA6000 will transform patient outcomes.
I thank all the patients participating in the trial. I am sorry you have had to endure your illness.
https://avacta.wistia.com/medias/kv40kul5b2
Thorn, it’s worth watching this video, it’s from the #AVCT 2022 AACR poster. If doxorubicin is present at therapeutically significant levels (in our case from release from AVA6000), then it does kill cancer cells as seen in these Human cell lines data.