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UK pioneering technology shown in Yale University study to regenerate dCELL® implant using the host's own stem cells but without the need to manipulate them or source externally Results published in PLoS one, a peer-reviewed journal from the Public Library of Science YORK, 14 June 2012 - Tissue Regenix, the regenerative medical devices company which uses animal or human tissue to replace damaged or worn out parts of the human body, announces that a pre-clinical study, undertaken by Professor Alan Dardik from the Department of Surgery at Yale University, using Tissue Regenix Group plc's ('Tissue Regenix' or 'the Company') patented dCELL® technology, has been published in a peer-reviewed paper and has demonstrated that the Tissue Regenix dCELL® matrix can deliver enhanced cell re-population compared to Vascu-Guard (Synovis, US) - a bovine derived matrix. dCELL® is a process which removes cells and other components from human and animal tissue allowing it to be used without anti-rejection drugs to replace worn out or diseased body parts. The pre-clinical study examined the types of cells that repopulated Tissue Regenix's proprietary dCELL® scaffold and compared these to Vascu-Guard, once both had been implanted. The study was performed using the Company's vascular patch that is currently approved for use in the EU. Findings highlighted that Tissue Regenix' dCELL® Vascular Patch was effective at attracting the right stem cell types quickly for the function they will have in the final tissue structure. This, in conjunction with the Company's own clinical observations, gives further support to the expectation that patients can get the benefit of stem cell repopulation without the significant issues and costs associated with using externally sourced stem cells.

http://www.investegate.co.uk/Article.aspx?id=201206140700153326F

USL PHARMA INTERNATIONAL UK LIMITED a wholly-owned subsidiary of UPSHER-SMITH LABORATORIES, INC. to be effected by means of a Scheme of Arrangement under Part 26 of the Companies Act 2006 Summary · The Board of Proximagen and the Board of Upsher-Smith are pleased to announce that they have reached agreement on the terms of a unanimously recommended offer by USL, a wholly-owned subsidiary of Upsher-Smith, for the entire issued and to be issued share capital of Proximagen (other than shares held by Upsher-Smith). It is intended that the Acquisition be implemented by means of a court-sanctioned scheme of arrangement under Part 26 of the Companies Act 2006. · Under the terms of the Acquisition, Proximagen Shareholders will be entitled to receive: for each Proximagen Share: 320 pence in cash; and up to a further 192 pence in either cash or Loan Notes by way of a contingent value right (a CVR)

Neuroscience researcher Proximagen Group (PRX) said that during the six months ended 31st March 2012 it has begun Phase I clinical trials of its VAP-1 antagonist treatment for rheumatoid arthritis and was awarded a grant to fund the research of its D1 programme in Parkinson's disease. The firm invested 3.1 million pounds in development and added that at the end of the period it retained a strong balance sheet, with cash of 48 million pounds. The shares climbed by 60p to 335p.

Bank of Georgia Holdings Buy 12-Jun-12 £66,300.00 David Morrison 6,000 @ 1,105.00p

Spirit Pub Company Buy 12-Jun-12 £49,999.72 Michael Tye 109,289 @ 45.75p

nvestors in Hyder Consulting were clearly pleased on Wednesday after the engineering consultancy company boosted the dividend despite full year revenue and profits coming in below analyst expectations. Pre-tax profit for the full year ended March 31st declined to £17.6m (2011: £18.2m), shy of expectations of £20.79m, on revenues of £277.3m (2011: £290.3m), short of forecasts of £291.75m. Basic earnings per share dropped to 36.48p from 39.29p. More positively, net operating costs fell from £272.1m to £260.2m year-on-year, the order book was up 16% to £363m, and adjusted operating profit increased from £20.3m to £21.0m. In addition, net operating margins climbed six percentage points to 8.7%. The dividend payment was increased by 16% to 9p per share from 7.75p, beating expectations of 8.42p. Chairman Sir Alan Thomas said: "The large proportion of our revenues and profits earned overseas has enabled the group to perform well in mixed market conditions. Hyder's strong order book, balance sheet and prospective opportunities give us confidence for the year ahead."

Barclays Capital upgrades Scottish and Southern Energy from equal weight to overweight, target price raised from 1235p to 1582p.

Alan Foy, CEO of Smart Metering Systems plc, commented: "We are absolutely delighted that TGP, the second largest gas supplier in the UK's I & C market, has decided to adopt the ADM™ solution. This is our second I & C contract to be announced in recent months and marks a step change in the adoption of the ADM™ solution as an industry standard. The ADM™ continues to trial very successfully with other I & C gas suppliers and energy brokers and we anticipate announcing further progress in due course. "

Smart Metering Systems (SMS) has secured a contract to supply its automated meter reading system, ADM, to gas provider Total SA's (TTA) commercial customers. The deal covers the installation of around 15,000 meters and will last for three years, which the firm equated in value to providing 250,000 domestic metres. The news follows a deal with SSE (SSE) for the installation and maintenance of 180,000 domestic units. Shares in Smart Metering gained 17.5p to 161p.

http://www.investegate.co.uk/Article.aspx?id=201206130700032087F

Professional services conglomerate Christie Group (CTG) announced that revenue growth had remained strong in the start of the financial year, benefiting from clients looking to de-leverage their businesses. The company noted a resurgence in large deal sizes, including the sale of the 918 pub Galaxy portfolio for 422 million pounds, for which it was an advisor. Christie added that it completed the acquisition of Orridge Business Sales during the period, making it the largest pharmacy agent and advisor in the UK. The shares leapt by 7p to 77.5p.

http://www.investegate.co.uk/Article.aspx?id=201206130700092360F

Shares in Quayle Munro Holdings (QYM) crashed by 87.5p to 487.5p after it warned that poor trading in the second half of the financial year ending 30th June 2012 is likely to result in the corporate finance adviser reporting a pre-tax loss for the period. The news comes after a previous announcement in March, which stated that the record performance of 2011 was unlikely to be repeated. However, the group remained hopeful that it will be able to announce some major transaction completions at the start of the new financial year

http://www.investegate.co.uk/Article.aspx?id=201206130830051766F

JD Sports Fashion (JD.) expects to take a 10 million pounds hit for the year ending January 2013 in operating losses from the acquisition of outdoor clothing retailer Blacks Leisure, together with an additional possible charge of 5 million pounds in restructuring costs. Meanwhile, the sporting goods company reported sales growth of 1.5% in the 19 weeks ended 9th June 2012, but warned that margins were facing growing pressure as a result of introducing greater discounts on products. Shares in JD Sports edged up by 3.5p to 615.5p.

Canaccord Genuity reiterated its "buy" recommendation for Novae Group (NVA) with a 415p target price. The broker said that the insurance underwriter achieved a price increase in US renewals of between 5% and 7% and noted that it is not as heavily weighted towards catastrophe insurance as its peers. Canaccord added that the shares trade on a prospective tangible book value of 0.8 times for the 2012 financial year, compared to larger cap peers trading on multiples of between 1 and 1.4 times. The shares rose by 7p to 368p.

Director's Dealing Secure Trust Bank PLC received notice on 12 June 2012 that, on the same day, Paul Lynam, Chief Executive Officer of the Company and Andrew Salmon, a Non Executive Director of the Company, purchased respectively, in the market 2,200 and 7,500 ordinary shares of 40 pence in the Company ("Ordinary Shares"), at a price of 1040 pence per Ordinary Share. Following this transaction, Paul Lynam holds 8,800 Ordinary Shares and Andrew Salmon holds 7,500 Ordinary Shares.

http://www.edisoninvestmentresearch.co.uk/researchreports/ABGUpdate130612.pdf

Advertising and media conglomerate WPP has bought a majority stake in Mumbai based Hungama Digital Services for an undisclosed sum. Hungama Digital Services is part of Hungama Digital Entertainment and specialises in marketing strategies, web design, digital marketing, search engine marketing, social media optimisation and communications strategy.