Member Info for MR.Spacetomato

PL75,

:0)

Stanman, you are welcome.

ST

AstraZeneca is in my view the big pharmaceutical company that will snap us. Maybe even a little bidding war?

I am even ashamed to suggest a price tag for Avacta when the brains behind it, Prof Alastair and others, are the geniuses behind the technology and it their baby. But, a a tiny shareholder I dare to suggest anything less than £10 billion would be an insult to the potential of this affimer technology. On the immuno oncology field alone this price would be peanuts, let alone this covid-19 story!

I urge anyone who has not spent at least a solid couple of days going over all the videos and reading material available on avacta, to do so. You will not bother with share price fluctuations anymore.

ST

Stanman, well said. Also, there is a very interesting presentation done in 2015 by Paul Ko Ferigno, Avacta CSO that does touch on the safety aspect and the excellent features of affimers. You can find it on YouTube if you type his name plus avacta and VIB.

Hurrah!
ST

spbhoy, sheertclass is shaking to his roots. He/she is insecure with their investments, to the point that they have to go to an BB where another good news just arrived and is now a potential threat to his plans. Bless.

It is like if we went to Sorrento BB and discourage them in their project yo try to beat this awful disease because we have our own path to follow and aspirations with avct. Well, that's just to be nasty inside. That doesn't mean we cannot say here, in our own BB, that we have a better candidate and, cry Hurrah! :0)

Anyway, I believe a little bit in karma, so there you have it, sheerclass. Shake, baby, shake.

ST

Wow, I come back and I see that a lot you guys want desperately us to be on Fox News! Please, calm down. I understand you want big jumps in share price, so fo I, but we will not get what a jump supported by a JV, but by short termers in who are just what we don't need. If you want to write to someone, instead of Piers Morgan, write to the GSK, Johnson & Johnson, Roche, Sinopharm, Pfizer, Sanofi, Merck & Co., Novartis, Takeda Pharmaceutical, Bristol-Myers Squibb, AstraZeneca, Merck Group to name but a few!

We need them in, not just a few bucks. I am sure Avacta with their connections will do a great job. They knew about the potential of using affimers as a vaccine way before today. I did mention it a while back and anyone who read about affimers in the thesis and in our company's website could see the potential.

I think a bit of calm now is needed. The ones doing the real work here are wearing the white scrubs. Prof Alastair is steadily taking us there and is a good skipper.

Take care all.

ST

PL75, stop it! You are giving me work...do you know how long it takes to log in to Barclays with pin entry and change orders?

;0)
ST

Phantom25, it was £62 limit sell price last night. £99 is ok; never be greedy, as my mum used to say. Bless her.

Yes, I sent the price so no one may borrow my shares to short them. My dealer is Barclays Mercenary Bank Plc.

St

ST

What a 20-pony show this is! Just safeguarded my shares with a £99 limit sell. No shorters shall borrow my shares.

This will be the best advertising for our AVACTA affimers ever and will propel our cancer therapies studies much faster with the extra cash!. So glad to be in.

Good luck all genuine investors.

ST

Doberman,
"2 - when people comment ' why are you commenting/posting/ramping/deramping when you are not a holder '. How do we know whether or not the person is a shareholder? We know that they have posted before but not that they are a shareholder or not!!"

Answer: Because they are not holders, otherwise, by undermining AVCT with their own comments mean that they are either deramping it because of their own agenda, or are totally deranged masochists typing texts on this BB in full leather gear with a snooker ball strapped to their mouths.

That's all.

St

MD.J.Morgan, I wonder what may be your true interest in posting your wisdom here? Clearly you are not invested, yet you are trying your best to deflate AVCT very-soon-to-be-super-duper-10-min test kit!

I for sure will not divest my profits here, and the gazillions I will still make here, and buy any pharma trying to find a vaccine (years away, for a virus that in your own words, mutates), say, like oxford biomedica, or else. We have done our work researching about affimers and the huge potential.

You are not the first buster who comes along this BB and try to take our money away for some dream chaser project; we have the real deal, dude. So, on your bike to shpil your views some other poor BB. Anyway, this is the last time I bothered to read or reply to your shpil. Bye.

St

BigBrenda, bye!

Yodaforce, absolutely. That's the difference between investors who did their best to choose a company where they believe there's potential from gamblers who see some growth, buzz and excitement in order to make a quick buck. Of course, there is no crime in trying to make a quick buck, specially now, but there is a gratifying thing doing it gracefully.

Good luck to all genuine investors here.

ST

Banjo, I must say I almost chocked on my cornflakes when I read your post! Immediately I conjured up a very good reason why you should sell, and it is free of charge!

Now, if you are genuinely worried about losing what you have on the stock market, then take Mark Twain's words as an advice, also free of charge:

“October: This is one of the peculiarly dangerous months to speculate in stocks. The others are July, January, September, April, November, May, March, June, December, August and February.”

My second thought? You can take your 10K and stick up your piggy safe; you will certainly need it, should we need to sell in a rush before you manage to sell ALL your 900K shares, should this beauty tank like a led brick into water! By the time you get to your phone/tablet, and try desperately to press that sell but at least 100 times after some "refresh tries", not being able to sell it, because all those sellers with smaller holdings will get out first!! Now, sweat on that thought!

ST

:0)

"The Affimer reagents have also now been studied further by Avacta and, importantly, this has shown that there are Affimer reagents that can work in pairs, both binding to the spike protein at the same time. This allows tests to be developed that detect both the intact virus particle and the detached spike proteins which become separated from the virus particle during the development of the COVID-19 disease, which may also be important in monitoring disease progression".

I am not sure yet what to think here beyond the stated above? I was yesterday, and I am sure some those PHDs at Avacta must be thinking laterally regarding their incredible affimers molecule and crossing it, just like in the cancer bomb-delivery technology, to say Azytromicine or Hydroxychloroquine molecules (well know in vitro virus killers) in a possible vaccine? Now, why not?

Cheers

ST

the potential to cause a very large epidemic in the absence of control measures (10–11). Transmission appears to occur primarily through dispersal of droplets from the respiratory tract (12), generated when the patient talks, coughs, or sneezes (4,5,10–13). Although large amounts of SARS-CoV have been reported in sputum and nasal specimens, which may account for transmission during coughing and sneezing (7,14), little is known about the load of SARS-CoV in the oral cavity and how the virus is transmitted during talking. Since sneezing and rhinorrhea are not common symptoms of SARS, and cough with sputum is only seen in the later stage of infection (1–3,13), oral droplets generated during talking may represent an important route of transmission.

We examined specimens derived from the oropharynx and oral cavity, including throat wash and saliva, from 17 patients with probable SARS (15,16). Using a quantitative real-time reverse transcription–polymerase chain reaction (RT-PCR) assay and fractionation experiment, we investigated the load of SARS-CoV in these samples and different components of the throat wash.

Please see the article for more:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323313/

I hope it helps.

ST

I was reading a few clinical studies on viral loads from salivary samples to get an idea, and the conclusion I get is that this virus multiplies very aggressively once we catch it, yet the symptoms may not show for many days. The viral load in saliva is very high from early stages, which helps to contaminate others.

Here is on of the academic articles you can easily find in google scholar:

Detection of SARS-associated Coronavirus in Throat Wash and Saliva in Early Diagnosis

Wei-Kung Wang, Shey-Ying Chen, [...], and National Taiwan University Hospital

Additional article information

Abstract

The severe acute respiratory syndrome–associated coronavirus (SARS-CoV) is thought to be transmitted primarily through dispersal of droplets, but little is known about the load of SARS-CoV in oral droplets. We examined oral specimens, including throat wash and saliva, and found large amounts of SARS-CoV RNA in both throat wash (9.58 x 102 to 5.93 x 106 copies/mL) and saliva (7.08 x 103 to 6.38 x 108 copies/mL) from all specimens of 17 consecutive probable SARS case-patients, supporting the possibility of transmission through oral droplets. Immunofluorescence study showed replication of SARS-CoV in the cells derived from throat wash, demonstrating the possibility of developing a convenient antigen detection assay. This finding, with the high detection rate a median of 4 days after disease onset and before the development of lung lesions in four patients, suggests that throat wash and saliva should be included in sample collection guidelines for SARS diagnosis.

Keywords: severe acute respiratory syndrome, SARS, coronavirus, CoV, Taiwan, perspective

Severe acute respiratory syndrome (SARS) is an emerging infectious disease that spread rapidly from China to >30 countries, including Canada, Singapore, Vietnam, and Taiwan, in the first half of 2003 (1–5). In the latest update from the World Health Organization, the number of probable SARS cases is 8,096 (5). The etiologic agent of SARS has been identified as the novel SARS-associated coronavirus (SARS-CoV) (6–9). The disease is highly contagious and has ...

Thanks, dryland for the cnbc link. Interesting their timetable for the easy-to-use tests to coincide with Cityva/Avacta's own timetable.

I would hope our directors would consider applying to move out of aim so we could attract some institutional investors.

Great VE day everyone!
ST

Testing



sbrearton1497GRZ "Having already created six working laboratory demonstrators for other applications, the research team says the technology still needs further adaptation and testing but could be available in a year at the latest". TOO BAD AND TOO EXPENSIVE!