RE: Omicron: ~8-fold Rise in Hospital Cases6 Dec 2021 23:48
@Woodstock1970, I have to agree. I’ve seen some reports that the Omicron variant is mild. However, I think it isn’t mild for a number of reasons and important points have been missed by some. Although South Africa falls behind in the vaccination program, the population at the epicentre of the Omicron spread has a high level of natural immunity due to previous infections (~70%) combined with second vaccine dosing (~25%). This suggests that Omicron dominance could be due to increased transmissibility and/or evasion of immunity. Weekly doubling hospital numbers are also worrying as is the impact on both younger and older age groups (comparison with Delta and previous waves). Infection severity is lower in the older group (could be due to a few reasons), but the worrying increase in hospital admissions in the younger age groups is indicative that this is not something to be taken lightly. Depending on the level of immune escape and the R0 values, the situation can become very critical very quickly. Something that could have an overwhelming impact on the health service especially the ICU and ventilator use. What would have been useful is an approved broad antiviral and highly accurate PoC tests. Thankfully SNG001 (a broad spectrum antiviral) is an ideal virus variant agnostic treatment that should have, in my opinion, been already approved under EUA.