Member Info for Malachi

Up and down like a chorus girls knickers, as my auntie used to say. This rise is based on no news whatsoever.

Special
So far you neither amuse nor educate. A tad arrogant perhaps?

I look forward to financial close by end of October. I will then feel more confident that PHE realy really is going to build that DMG. Not too much to hope, is it?

I hope not. I am staying put.

Down 13%. The sell off follows Dysons remarks. If matters are as serious as he makes out this should have been an RNS. I think he was either stupid, which I think unlikely, or this was deliberate for reasons best known to Dyson.

DesertW
Agree. There is no place for these chummy payoffs for doing SFA. TY should have no further part in PHE.

I have just listened to AN. A most impressive presentation on a device that has a limitless future. Happy days around the corner for all, patients and LTHs.

NutH
Not too bothered about age, but probity / integrity counts for a lot

Duke
"HiPerGuard also ensures flexibility of system design and future energy source implementation, for alternative energy sources such as hydrogen" suggests to me that the AFC linked system is not yet off the drawing board, and is something for the future. But at least ABB will be using AFC's system.

Senstalka
"with news due on a myriad of fronts, each one of which could catapult the SP to new heights on its own merit."

I would be pretty pleased if we could get back to the old heights, let alone new ones.

Elderly
Each of your 4 posts since Jan 2019 have alluded to FDA/ MHRA somehow having financial benefit from not pressing forward with / delaying approval for Parsortix. Where is the evidence? Simple question; now answer it.

ElderlyBird
What is this rabid nonsense about FDA/MRHA not wishing to approve Parsortix because Cancer is a cash cow etc? Neither organisation makes any money from from pharma, and in suggesting otherwise you insult the intelligence of other posters. Happy to see your evidence, otherwise a further period of absence from the board will be appreciated

Jam tomorrow, very thinly spread.

How difficult is it to change feedstocks - say plastic to tyres? Does it require a major modification to DMG?

Ent
Many thanks for this clear summary

Sorry to have said the same thing twice, initial offering disappeared.

Researcher
With respect I am not wrong. Parsortix does not collect or use cfDNA, and neither is it a possible downstream test for Parsortix .Parsortix does indeed capture CTCs. In the CTCs there is high quality entirely intact (not epitope dependent) DNA as opposed to the degraded fragments ie cfDNA examined by GRAIL. The cell can even be cultered There is no possible synergy between the two tests that I can see.

Researcher
I don't think, with respect, i am wrong. In the absence of tumour spread , ie circulating tumour cells with metastasis (apart from perhaps bone marrow tumour cells) there will not be any CTCs to screen. There may be, however, cfDNA from breakdown of tumour cells in situ. This cfDNA is what GRAIL hopes to use to determine if there is tumour, and perhaps its origin.My view - and the study may demonstrate this, that the spec and sens of this test may disappoint.

Interms of malignancies, Parsortix is of use ONLY in determining genetics of pre - diagnosed tumours. It is not a screening test.

Dr A
Thanks for this. Your comments make sense to me and are reassuring.