RE: INFORAAA Study3 Jan 2019 14:13
Dan - my understanding was that the RAAA was originally running parallel to the phase III ARDS studies, but looking at different patient groups entirely.
The trials were put on hold once the issues with the ARDS studies became apparent, but I'm not confident that YODA and a subsequent phase III ARDS trial will do much to de-risk the INFORAAA trials... that may well be the case, and if so then it would have proved to be a sensible move to pause those trials.
Of course, if that is the case then they may need to scrap any progress that was made with the RAAA studies and start from scratch with different patient criteria... in much the same way as a new post-YODA ARDS trial?