Member Info for JOHNO77

Hope you meant 'Near Four Pounds......!!!'

Bosh!!

C'mon, let's have a BLU finish!! :)

He is still very much here but has other commitments so can't be on the bb's day in day out.

The MTA partners will likely be doing their own similar experiments including control measures so we will no doubt soon find out what they have been up to.

So basically the rns was very much NET positive IMO.

I have verbal diarreah this morning so will sign off for now, haha.

GLA.

Vander, surely it's important to remember that Nuvec is not limited to using TNF-a.

N4 Has proved that it can deliver TNF-a in-vivo but in the future it could be used to deliver countless other treatments too.

The more i think about this the more i'm convinced that this little drop is just an oppo to pick up cheaper shares. The covid trial did not work but neither did the positive control. Essentially nothing has changed apart from Nuvec is now proven to work in -vivo in a tumour shrinking model and N4 now is in advanced discussions with a 3rd MTA....

The vaccine work is continuing as before under the directions of the partners who have better expertise and resources that us.

Thanks Vander, this bit from the summary was interesting, it seems that specific targeting is required to reduce the toxicity and Nuvec can cater for that:

'Nanomedicine, briefly mentioned earlier in this review, may revolutionize future cancer patient management (Ferrari, 2005). Since most nanoparticles do not extravasate well, tumor vasculature targeted delivery of TNF-a using a nanoparticle carrier is probably the most feasible and appropriate strategy. The future of nanomedicine lies in multifunctional nanoplatforms which combine both therapeutic components and multimodality imaging (Cai and Chen, 2007). The ultimate goal is that nanoplatform-based agents can allow for efficient, specific in vivo delivery of drugs without systemic toxicity, and that the dose delivered as well as the therapeutic efficacy can be accurately measured non-invasively over time.'

Especially now N4 has been knocked down to a piddly 9mill mcap......

Final results this year were rns'ed 12th Jan 2020, so not long to wait either way

Have noticed Bluestar issued an EOY Esports portfolio update rns last year on the 23rd Dec. Obviously that was under Tony's tenure but it would be great if Derek did the same thing. A closing PF update would be great and an official Dynasty progress update is long overdue.

Great summary there from N4.

Clear tumour suppression from the Nuvec® loaded with 20ug of TNF alpha pDNA :)

'These results confirm the in vivo ability of Nuvec® to deliver a plasmid DNA to appropriate cells and to effect
transfection and release of a clinically relevant product, in this case TNF alpha.'

Red open didn't last very long did it? lol

Dynasty were valued at 50m usd (circa 40m gbp) in April, given their progress to date and the new business won you would think the ipo would be at least 75mill (conservative).

19mill current BLU valuation
less 10 mill (13% holding of dynasty £75m)
less 3mill (approx value of other investments)
leaves only 6mill in our mcap for Satoshipay. An absolute paltry amount given recent progress & projected 2022 newsflow.

Despite the recent move, current mcap still looking very skinny indeed.

Wow Dave i have just seen that one of the creators of Dunia Games was Crispin Tristram, co - founder of Dynasty. $500m revenues....

Him and Matt Lodge certainly have great pedigree, the management team look fantastic....Dynasty could be an absolute monster.

IMO EZJ is a steal back down here again at peak covid levels. Omicron will be over in a flash.

Plus let's not forget gene therapy (MTA with a global pharma).

People were invested here long before Covid was even on the map. The lack of a result on the positive control tells it's own story. What Dan said is right, the oncology results and news of 3rd MTA would have propelled the market on their own.

I've been buying more low 5's and will,buy more in the 4's if it goes there.

4p 7m mcap is a steal given the current situation.

A 9 million valuation for a small cap with good in-vivo oncology results and 2 advanced MTA's (and one more on the way) doesn't sound too bad does it??

Blu is certainly a much better proposition than Vela but down at 0.05p Vela seemed a good level for a small punt, given they also have the anticipation of near term news.

Good to hear that Bowlers.

I actually had a little dabble in Vela myself this week. Have bought a small stake in case something comes off from the licensing talks.

GL