The Yourgene QS250, supplied by Yourgene Health performs:
Fragment length analysis Accurate Library quantification Enrichment of DNA of interest All with a single piece of equipment
Automated DNA quantification of ALL samples simultaneously Time and reagent saving Fast run time leading to decreased turnaround time Accurate DNA quantification Integration with automated library preparation platform Generates clean fragments of a precise size range of interest Enriches fetal fraction by two-fold Allows for high-multiplexing in the future Allows for more consistent analysis, further reducing failure rate Reduce or eliminate the hassle and wasted time & expense of sequencing off-target fragments Lower pool concentrations needed (from only 100pM), decreasing failure rate
From the website :- Unique to Yourgene – a game-changing NIPT sample enrichment step with the Yourgene QS250 – enriches fetal fraction two fold!
Yourgene are looking for new select laboratory partners to implement the new IONA® Nx NIPT Workflow. Are you looking for:
A flexible and scalable NIPT solution that will grow with your demand – from 16 to 48 samples per run High performance CE-IVD screening test with >99.99% detection rate Extensive clinical content menu Smaller instrumentation footprint Automated and manual workflow options Unique to Yourgene – a game-changing NIPT sample enrichment step with the Yourgene QS250 – enriches fetal fraction two fold! World class global technical support and back-up service lab
A very tiny part, but massive to the expecting parents, will be the need to not be asking for further samples if the processing messes up, as they will have enough already to rerun the tests. I can’t remember if the workflow is quicker as well, 2 days rather than 3. I would need to research that again to double check.
Massive cost saving, able to analyse less of the sample and get super accurate results. I think they will go for the cost saving in tubes as the main driver. 16-20 dollars compared to 1-2 dollars with Ranger Tec. That’s a massive saving with millions of samples being processed.
If Ranger technology is as disruptive and revolutionary as Yourgene are saying, and I have no reason to think otherwise. One mega lab in the US is onboard, I am sure the second will follow shortly. We must be in the cross hairs of at least Illumina and TF. IMO it’s either a case of being swallowed up by one of the BIG companies, or we will see a rerate in SP massively. LR wants his 500m market cap, this may just be what gets it for him.
It’s clear we just need to wait now until there is material news surrounding the Ranger Revolution. Hopefully confirmation of the second mega lab coming onboard. On a side note, the rise yesterday, RNS this morning, we have more leaks than the titanic. Pmsl. Once we get some decent news the SP will go north quickly.
The market is clearly going to wait for the DHSC payment and also whether Vatic Health get the go ahead to sell in the USA. There is a chance that 1 of these or even both potentially may not happen. Imo I can’t see payment not coming, just how long it takes is the unknown. GLA