Member Info for EmeraldCarrots

Do they!

Angle PLC Interim Results for the period ended 30 June 2023.

"-- Installed base of Parsortix(R) systems increased to over 290 with cumulative samples processed of 192,000 as at 30 June 2023."

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Over 190 machines as at 30th June 2023.

So almost 9 months ago. How many machines now? How many disposable cassettes now?

Do any of the 50 plus Co's IN THE WORLD that offer DNA analysis of blood want to add the analysis of the Circulating Tumour Cells (CTC's)? Do they want to offer a re-badged Parsortix machine to their clients so they catch the CTC's and do the additional analysis to get the full picture? They should want to as it would increase sales and give their clients all the available information (CtDNA analysis of blood plus DNA analysis of the CTC's = the complete picture).

All IMHO.

Around $300 per 1 use cassette how do we know how they have been doing?

I'm sure the shorters on here will come up with something from thin air.

With 190 machines out there in the World a load of cassettes may be being used etc....

All IMHO.

Good to me. Took a chance and did not sell any before the results.

CWWX

Blue in the US

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Just gone blue here too!!!

Nice to be paid $7 billion in advance. Presumably they get interest on that!

Only down 0.82% now.

Turn blue, you know you want to!

The sp has been here 3 or 4 times before in the last 2 years. Nice 30% plus.

Roche or some such their sp will be back to over 30p in 30 mins.............

Angle Plc have the tech to catch circulating tumour cells for analysis. Most of the Companies that currently offer CtDNA blood analysis don't offer the same for the CTC's simply because they do not have a system that can catch the CCTC's, or at least ones that are LIVE, intact and not contaminated by the very system used to catch them!!

Some sort of deals must happen.

All IMHO.

Only 0.5% down now. Nearly there!!

Exellent!.

Incredible!

To guide treatment decisions. As you can read they are using "Illumina technology" to look for "actionable DNA" which can be targeted by modern drugs. See here:-

https://www.bbc.co.uk/news/uk-wales-65377533

and

https://www.bbc.co.uk/news/health-68624334

In Angle's RNS announcements of 4th and 20th January Angle have discovered that both their study (RNS of 4th Jan) AND other previous studies (RNS dated 20th Jan) showed actionable DNA is sometimes found only in the circulating tumour cells (CTC's) and NOT in the blood CtDNA!! Companies like Illumina do not have a system that can catch LIVE intact cancerous tumour cells to analyse. Angle of course do. So what do you thing they will do next???

https://www.youtube.com/watch?v=cnQ6M05BiBY

All IMHO

Mutational signature profiles, and therapeutic targets compatible with those found in matching primary tumor samples.".

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What is genomic heterogeneity?

A term that describes when different gene mutations (changes) cause the same disease or condition.

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So the circulationg tumour cells Parsortix caught were the best samples and most like the primary tumour.......... better that Cellsearch.

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Genomics

Volume 114, Issue 6, November 2022, 110500

https://www.sciencedirect.com/science/article/pii/S0888754322002452

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All IMHO.

Did not notice that. Maybe I should try posting blatant lies like you do on a regular basis!

"Molecular analysis of circulating tumour cells—biology and biomarkers"......................

Liquid biopsy and circulating tumour cells MORE AND MORE IN THE NEWS..........

https://www.nature.com/articles/nrclinonc.2013.253

I can't spare 30p at the moment.

LOL!

TwoGood2Die.

Not allowed to use your smart phone at school then now I take it?

Not me, at least today. Do you think the takeover rumours are true?

Circulating tumour cells which is needed to get the "full picture" when they don't even have a way of catching LIVE intact circulating tumour cells to test in the first place! They only offer CtDNA analysis of the general blood which can miss actionable DNA which light show up in the CTC's! To get the full picture BOTH the CTC's and the CtDNA in the blood need to be analysed.

THEY HAVE A MAJOR PROBLEM, DON'T THEY!

They need to do a deal with Angle Plc I believe!

All IMHO.

(circulating tumour cells) to the systems they sell at the moment for the DNA analysis of the general blood. Analysing the general blood can miss actionable DNA that is sometimes found in the CTC's. These systems are now starting to be used ***by the NHS*** in the UK.........................................!!!

In this article the author says "Lucci foresees that ctDNA and circulating tumor cells will be used in combination to offer the best picture of what’s happening with a cancer inside a patient.". Angle have made the same comments. See Angle Plc's RNS's dated 4th and 20th Jan.

https://www.mdanderson.org/cancerwise/liquid-biopsies--understanding-ctdna-and-circulating-tumor-cells.h00-159463212.html

To do this they need a way of capturing the CTC's. They need to be uncontaminated by the very process that catches them. When caught using Angle's Parsortix system 99% of the cancer cells are alive and intact, ideal for testing. So, to offer a system that gives the full picture they could:-

1. Do a deal with Angle Plc and offer the Parsortix machine alongside the one they sell so it catches the CTC's.

2. Re-badge the Parsortix machine so it looks like it is their tech and do the same.

3. Re-design their machine to incorporate the Parsortix tech so one machine gives the full picture. This would use the Parsortix cassette which needs to be replaced after every test thus vastly increasing revenue.

There you have it.

IMHO Angle Plc are "sitting on a gold mine". The first DNA analysis Co. that offer this "full picture" process will one step ahead of the competition.

All IMHO.