Member Info for EmeraldCarrots

Reducing my holding what had started to get rather too large! However AGL in still my biggest investment..............

To me there are 3 things that are really important here. First and second we know they are talking to both Eisai In. (a top 100 Japanese Company AND now Astrazeneca. Then to me the announcement of 4th January. Why? Because ANY Company doing a drug trial involving a metastasized cancer SIMPLY MUST AS THAT RNS says carry out "Combined DNA Next Generation Sequencing of CTCs and ctDNA from the same blood sample". See:-

https://www.lse.co.uk/rns/AGL/breakthrough-clinical-results-b0km788ah9aflqm.html

Failure to do an analysis on both the CtDNA and CTC's (Circulating tumour cells) after AGL's RNS explaining the additional important information they found is NOT AN OPTION. It would be a complete dereliction of duty!

When the first contract lands for this service the £1.60 spike on FDA approval might again be reached!!!!

All IMHO.

See these, and where this is going I believe..............

https://www.lse.co.uk/rns/AGL/contract-announcement-with-eisai-inc-49aplx5us0gzg6h.html

https://www.lse.co.uk/rns/AGL/new-commercial-agreement-with-astrazeneca-edeymgqdtcshqde.html

The following one is ALL IMPORTANT !!!! Join the dots............

https://www.lse.co.uk/rns/AGL/breakthrough-clinical-results-b0km788ah9aflqm.html

Up more - 32%.

18p plus on the cards.

All IMHO.

Buys flooding in now folks!!!!!!!!!!!!

Up 26.53%

Astrazeneca contract RNS!

Rececent announcements regarding HER2..........................

Join the dots...........

========================

Also very important about the RNS of 4th Jan "Angle PLC Breakthrough clinical results (5877Y)", see link below.:-

Companies doing Cancer drug trials will NOW want standard blood CtDna analysis ***AND*** Circulating Tumour Cell analysis for even more information on how their extremenly expensive drug trials are doing etc. OF COURSE they will want the maximum information available in order to log for the future and evaluate how their drug is performing!!! The IS A NO BRAINER.

And that is just one of Angle's offerings................................................

https://www.lse.co.uk/rns/AGL/breakthrough-clinical-results-b0km788ah9aflqm.html

All IMHO.

Yipeeee!!!!!!!!

Up 32.65%.

Astrazeneca contract!

AstraZeneca agreement !

https://www.lse.co.uk/rns/AGL/new-commercial-agreement-with-astrazeneca-edeymgqdtcshqde.html

Cjh6309

"And if it goes up another 30% tomorrow, then who’s the idiot! Cannot understand people who sell too quickly knowing the strong possibility of positive news just around the corner.".

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If it goes up more tomorrow then I'm ok with that. I'll settle for the 70% I've banked.

Good luck all.

I bought @ 18.5p and sole @ 32p !

Carter19.

Eh?

Hello.

Place your bets!

Hello.

Bantham.

As I said clearly Mr Newland and the board see the massive potential here for this CellKeep™ slide or they would not have applied for patents in the EU and USA. A simple, by the looks cheap to make plastic device which is far gentler on the cells that end up on the microscope slide. Not only that, but the cells are also concentrated in a smaller area. So, any cells are far less likely to get damaged/killed and are in a smaller area so easier to find! Plus, it says using the device should save on the cost of antibodies as less are needed. Three very positive points for adopting the use of this device! The RNS says the device with the "Portrait Plus CTC staining kit" and Mr Newland says they might offer it separately. Offering it separately would be potentially handing the advantage the device gives their Parsortix machine to some competitors. Having said that competing methods to capture circulating tumour cells are complicated and come with very specific instructions on how to use the particular system. Unlikely to say "then use an Angle Plc CellKeep™ slide” to obtain the cells for viewing with the microscope! I think Angle Plc should immediately offer this device Worldwide through distributors. It could and up as a standard device for use when the cells to be viewed are liable to get damaged during the normal centrifuge process. Sales of potentially tens of thousands world-wide.

https://www.lse.co.uk/rns/AGL/us-and-eu-patents-for-innovative-cellkeep8482-slide-3s3v2c8b8y6u32u.html

All IMHO.

Bantham.

Clearly Mr Newland and the board see the massive potential here for this CellKeep™ slide or they would not have applied for patents in the EU and USA. Having had more a think it could be a very major part of Angles revenues. In fact Worldwide something like this cheap to make plastic "slide" could end up being the biggest money maker for Angle. This device, which obviously is far more gentle on the cells it captures on the slides so they are less damaged, and as the RNS says concentrates the CTCs into a smaller area on the slide (making processing cheaper) could easily become extremely popular............. WORLD WIDE. That is a big market. Sales could in time be in the tens of thousands, or even more.

As ANGLE Chief Scientific Officer, Karen Miller said "This technology is a significant advancement over current standards for CTCs and has the potential to capture other cell types from body fluids such as blood, urine or cerebrospinal fluid, for subsequent analysis".....................................................................................Holy **it.

MUCH more significant than the 4.12% gain today which is a total joke.

All IMHO.

Angle have clearly put a huge amount of effort creating this "Portrait Plus CTC staining kit" which includes the innovative CellKeep™ slide referred to in todays RNS. As Andrew explains the kit standardises the stains used, gives the stains greater shelf life (as they are in the form of a dissolvable tablet) and uses the now patented CellKeep™ slide to reduce circulating tumour cell (CTC) loss !!! As he explains the patented CellKeep™ slide makes the Parsortix system far more efficient compared to using the industry standard way which can damage and kill the CTC's. I don't think it's possible to get a better CTC sample (99% alive and undamaged) for subsequent analysis.

https://www.youtube.com/watch?v=hxu_XmeIpDA

All IMHO.

Or this:-

Https://www.lse.co.uk/rns/AGL/us-and-eu-patents-for-innovative-cellkeep8482-slide-3s3v2c8b8y6u32u.html

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