RE: pt 120 Mar 2020 11:22
pt2
a test that would take just one hour. E25Bio, a Massachusetts-based biotech company, which creates rapid diagnostic tests for diseases like Zika and Dengue, raised $2m from Khosla Ventures to develop a speedy Covid-19 test.
Scientists from the University of Oxford’s Science Engineering department have also developed a rapid test that can give a result in half an hour, and have validated the system with clinical samples at a Shenzhen hospital. An Irish startup, Assay Genie, is also developing a test that could detect the Covid-19 virus from a single drop of blood in 15 minutes.
Antibody testing
In addition to being able to more quickly test if someone currently has the virus, it will become increasingly important to test for antibodies that would show if someone has had the disease.
Those people, who would be likely to have immunity from the disease, would be able to resume working and contact with vulnerable people. The sooner this kind of test can be brought on a mass scale, the sooner lockdowns can end and the economy can begin to recover.
Laboratory methods for diagnosing Covid-19 follow one of two methods — either detecting the virus itself, usually from a nose or throat swab, or detecting the antibodies that our bodies have developed to fight it. Antibodies typically develop around 7 days after the infection (see below) but last in the body a long time, so that a previous Covid-19 infection should be detectable weeks or months later.
Singapore was the first to use an antibody test, developed by researchers at the Duke-NUS Medical school, in February but now several companies are working to provide simple test kits using this method.
BioPanda Diagnostics, based in Belfast, was reported by Wired to be in talks with the UK government to supply a simple blood test that could test for Covid-19 antibodies in 10 minutes. The test kit, shown on the company’s website, looks as simple as a pregnancy test, a plastic case with blue lines appearing in a little window for a positive result.
BioPanda is a seed-stage company, launched in 2011, which, according to Dealroom, has just 4 employees, so it remains to be seen if the company could produce these tests on any mass scale.
AlphaBioLabs, a Drug. alcohol and DNA-testing company based in Warrington in the UK, says it is bringing out a £125 fingerprick test to show in 15 minutes if someone has developed antibodies against Covid-19. The test, initially available only to businesses, will be available by the end of March, the company said.
Beware the snake oil
Chris Whitty, the UK’s chief medical officer, told a press conference on Thursday that the UK government is currently in talks with several companies about antibody tests but warned that “We are not yet sure whether the {tests] currently on the market are the right ones”.