Member Info for Bella6532

Benbow27 ...these are my estimated monthly volumes/sales based on my orders. The Actual figure is per PXS reportings.
I suspect the sudden drop this month is H&B stores closing as we had monthly volumes in the 2000's prior to H&B coming on board. If H&B took an order in the first week of April, that would be just prior to lockdown. I do think the order number system is based on per pack shipped per order. So if customer A orders 10 packs the order number jumps up by 10. If customer B orders 1 pack then the order numbers go up by 1. This allows the logistics warehouse used by PXS to easily charge per unit in/out/stored.

Oct-18 2347 £6,988
Nov-18 2225 £6,625
Dec-18 2416 £7,193
Jan-19 2316 £6,896
Feb-19 3045 £9,066 Increase due to H&B & Amazon UK
Mar-19 4780 £14,232 Increase due to H&B & Amazon UK
Total 17129 £51,000 £51,000 ACTUAL

For the Year 2018/19 Total 31559 £97,997 £98,000 ACTUAL

Apr-19 4745 £9,691
May-19 5160 £10,538
Jun-19 4886 £9,979
Jul-19 4668 £9,533
Aug-19 5007 £10,226
Sep-19 4912 £10,032
H1 2019/20 Total 29378 £59,999 £60,000 ACTUAL

Oct-19 4767 £9,736
Nov-19 5136 £10,489
Dec-19 5781 £11,807
Jan-20 5635 £11,508
Feb-20 5991 £12,235
Mar-20 5854 £11,956
H1 2019/20 Total 33164 £67,731 ESTIMATED

Apr-20 5316 £10,857 Includes UK 3 weeks CV Lockdown
May-20 2259 £4,614 All during Lockdown
H1 2019/20 Total 7575 £15,470 ESTIMATED

rip@burn...The World Health Organization initially recommended against the use of non-steroidal anti-inflammatory drugs (NSAIDs) in patients with COVID-19. However, they reversed that recommendation several days later and no longer recommend against ibuprofen or other anti-inflammatory drugs, including aspirin.
‘The use of non-steroidal anti-inflammatory drugs (NSAIDs) in patients with COVID-19
19 April 2020
Conclusion
At present there is no evidence of severe adverse events, acute health care utilization, long-term survival, or quality of life in patients with COVID-19, as a result of the use of NSAIDs.’
https://www.who.int/news-room/commentaries

There is still some confusion out there on this subject and I just feel it might have some mileage for PXS to send a nice little note out to all their customers/past customers highlighting the benefits of FF vs Aspirin and throw in a couple of links to our study, the WHO stance on Aspirin now and reports in the press such as the one you posted from the BBC...
No harm in standing behind your own science and reiterating the benefits of FF and the information (and there's a ton of it) on the Fruitflowplus website.

From what I can see, there are no trials currently taking place for FF by PXS or Bi Health in relation to Covid19.
However, on 13 March 2020 DSM completed a study to determine the effect of 4 weeks daily consumption of Fruitflow on changes in plasma levels of fasting Trimethylamine N-oxide concentrations (TMAO) but no results have been published yet.
https://clinicaltrials.gov/ct2/show/NCT04160481?term=Fruitflow&draw=2&rank=2

Provexis Fruitflow v Aspirin Trail results published in: European Journal of Clinical Nutrition 23 November 2016
‘A randomised controlled trial comparing a dietary antiplatelet, the water-soluble tomato extract Fruitflow, with 75mg aspirin in healthy subjects
N O’Kennedy1 , L Crosbie1 , H-J Song1 , X Zhang1 , G Horgan2 and AK Duttaroy3’
https://www.fruitflowplus.com/wp-content/uploads/2016/11/aspirin-study.pdf

For any newbies who might not know, X Zhang who worked on the PXS FF/Aspirin trial above is
Now Group Director, Science and Technology Centre; Director, Nutrition and Health Research Centre at By-Health Co., Ltd
‘Prof. Xuguang (Felix) Zhang had his PhD in Human Nutrition (Medicine) in the Rowett Institute of Nutrition & Health, Scotland, UK. Before he joined in By-Heath (China), he had worked for over ten years on medical/functional food development for FRDC Fonterra (NZ), University of Aberdeen (UK), Science in Sport Plc (UK), and Provexis Plc (UK). Prof. Zhang had also led scientific research projects in CVDs and metabolic health when he worked as a Research Fellow in Rowett Institute. In Provexis Plc, working as a Senior Research Scientist, Prof. Zhang and his team delivered their core functional ingredient FruitFlow, which won the first new health claim in Europe under the Article 13.5 EFSA. Prof. Zhang is a Registered Nutritionist (Nutrition Science) in the UK. Now he is working as Group Director of Science and Technology Centre, Director of Nutrition and Health Research Centre, By-Health Co. Ltd. He also works as Adjunct Professor, Director of Nutrition and Anti-aging Research Centre, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences. Prof. Zhang is the national expert committee member of Health Aging, Healthy China Research Center and executive committee member of Chinese Nutrition Society.’
https://cn.linkedin.com/in/felix-zhang-a7ab8062

Tarka.. Totally agree but neither DSM nor PXS will push that message. As a customer of Fruitflow+O I have asked, and I know several friends who have also asked, PXS and DSM if they feel it is safe to continue to take Fruitflow but no responses. Does this mean they don't know? If they feel the science stacks up and it is safe to continue to take they should ssy so and send out a note to their customers to reassure them.

It seems the sooner SNG001 can be administered the better because when this virus takes hold it can cause some very nasty long term ailments.
https://www.vox.com/2020/5/8/21251899/coronavirus-long-term-effects-symptoms

I think most people now have an idea what Covid symptoms to look for but do they really know what the Covid19 virus can lead to.
https://www.vox.com/2020/5/8/21251899/coronavirus-long-term-effects-symptoms

Closed Period remember...

Alfista...so you've spoke to IF then? Care to share?
Others have received the... Can't comment and referred to last RNS...

A strong immune system is the body’s defense against non-desirable and illness-causing agents like microbes and viruses. Several micronutrients such as the vitamins A, B6, C, D and E, omega-3 fatty acids (EPA and DHA) and beta carotene, support the development and maintenance of a strong immune system and an adequate intake can boost immunity. Therefore, during these difficult times, we expect that the need for these micronutrients as single vitamins or multivitamin solutions will increase.
https://www.dsm.com/markets/human-nutrition/en/events/covid-19-communication.html

Sorry I should have also mentioned that just because 6 are in the ACCORD programme it doesn't mean if SNG is currently not it it won't be considered once results are in. If SNG is ahead in their trial they won't ask them to put the breaks on until 6 others catch up and they've already fast tracked the SNG trial anyway...
Would SNG have mentioned ACCORD in one of their RNSs if they were in it unless they prefer to stay dark on the subject and have just given enough info like fast tracking to satisfy market news rules.
Guess we won't know either way until we know...

https://www.gov.uk/government/news/covid-19-treatments-could-be-fast-tracked-through-new-national-clinical-trial-initiative

Are you sure we aren't in it... We've been fast tracked and our chappie at Southampton mentioned...

'Fruitflow is a natural dietary antiplatelet ' What!!!!?????
I rest my case...DSM have no idea how to message Fruitflow!!!!
And this is from Cosimo Palumbo, Dietary Supplement Segment Lead at DSM Health who says he's a Pharma and Dietary Supplement Enthusiast | Brand Ambassador | Seaplane Pilot and is a Pharma and Dietary Supplement professional with extensive Sales & Marketing experience.
My guess is he's using a ghost writer in the Philippines which is common practice these days....

Sanibel... Yes FF helps maintain normal platelet aggregation... So it helps prevent the abnormal activation which would lead to abnormal aggregation. It doesn't stop the activation and aggregation when needed to stop bleeding when you cut yourself etc. This is why aspirin can be so dangerous because it can lead to bleeding and a less effective aggregation when necessary. You only have to talk to people who take aspirin and other blood thinners how difficult it can be to stop a simple small cut from bleeding....

Worth a read...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334395/

Pumpky... Thinning blood is a sloppy description... Both aspirin and FF prevent unwanted platelet activation whereby they become spikey and able to stick together to form a clot. Smooth platelets allow the blood to flow freely.

What about all the media medics who had a private one on one with O'Kennedy and the science behind Fruitflow including Dr Hilary who is on TV daily...
Some on here might wish to give them a prod since their view on Fruitflow are clearly posted on the Fruitflow plus home page...

For those familiar with the FF science it works on 3 levels where as Aspirin only on 1 which again could be a plus factor.

PXS has already been sent the Aspirin trial info...
If their claims and science behind Fruitflow stacks up and one would assume they have access to the trials Bi Health have conducted too then there should be a massive push to promote FF as a way of reducing the risk of covid19 secondary side effects such as blood clots and strokes...

'In summary, the early use of aspirin in covid-19 patients, which has the effects of inhibiting virus replication, anti-platelet aggregation, anti-inflammatory and anti-lung injury, is expected to reduce the incidence of severe and critical patients, shorten the length of hospital duration and reduce the incidence of cardiovascular complications.'
https://clinicaltrials.gov/ct2/show/NCT04365309

Wheels... Good try but don't think so. DSM are probably too busy selling shed loads og Vit D.
IF is pulling the closed period card...and he's too busy acting as customer service and mktg manager for FF+

From Lansdown Partners Holding RNS.:
'4. Full name of shareholder(s) (if different from 3.)v HSBC Client Holdings Nominee (UK) Ltd and Morgan Stanley Client Securities Nominees Limited'
Not quite sure how it all works but someone wants to make their monthly/qrtly/H2 look a bit better....

Everhopeful... Yes I did say that way back then and I honestly believed it could be done. If you've had conversations with IF then you'll know why I have questioned the direction or lack of.
For me and I discussed this many times with him it's the name Fruitflow which is the biggest problem and he was too fixated on trying to copy Ateronon, put everything out to so called friendly experts. DSM developed the FF+concept but they haven't taken it any further due to lack of take up. iHealth has been hugely successful for DSM but no FF...yet time and time again IF said FF was DSMs gold standard!!!
Yes I used to be hugely positive but not now. Should China pan out that will be brilliant but I'm sure any wiff of big numbers will lead to PXS being farmed in prior to any volume sales being realised.
Alfista I admire the fact you have remained positive and fight from the companies corner and I do hope all shareholders will be rewarded one day but it's been a very long hard struggle for many and doesn't look good when news dries up and the only person with whom shareholders have had any dialogue refuses to respond. Just not a good look right now.