Member Info for Bella6532

Manifesto...I sort of agree but it's a dual edge...will deals be struck before Reg Authority signs off on it...
Both go hand in hand hence I think that's why the reference by Richard to 'detailed talks ongoing with Regulators (esp.MHRA/FDA) and numerous Pharma'...

If you look at the patent, SNG001 is a formulation of several products plus the inhaler itself. There are lots of companies who can produce such a product, we don;t actually need a Pharma to do this and Pharma does a lot of outsourcing. Now if you have several Pharmas in discussion, why would you give it to one if you could licence to several? Remember little old tech company ARM....
Now having said that, I think we should look at what sort of company SNG is - research not sales/marketing. So perhaps the option they will look for is sell the IP and/or company to the highest bidder or Licence it out to one or more pharma and live off the income which can finance new research on an ongoing basis.
Now going back to my comments, Govts do have a sway and as we've seen are prepared to bet on new vaccines/tests...if the UK Govt gives SGN and/or Pharma a LOI (Letter of Intent) to purchase X amount based on Regulators approving SNG001 for Emergency Use (at miniumum) then that would I'm sure drive negotiations and if the Govt at the same time gave the Regulators a nod and wink to give Emergency Use (at minimum) to save lives/get people back to work...there could be a bit of pork belly funding here too for you guys...then...well...

Not saying it will happen this way, but stranger thinks have happened in this funny old World like Govts putting so much faith on the New DnaNudge...it didn't take them long to get in did it????

The Uk Govt is putting it's faith into a new DNA Test produced by a company called DnaNudge....
https://www.gov.uk/government/news/roll-out-of-2-new-rapid-coronavirus-tests-ahead-of-winter

mmm!...no big pharma here just a non-listed very very small Mom and Pop type online business which proves to me that they will go down any route big or small to try and get this Covid crisis under control and keep people (especially NHS and front liners in work).
A test that doesn't work is more dangerous IMO than a treatment or drug that isn't effective. So my point is, if the powers to be are putting their faith in the new DnaNudge Test Kit, then surely they must be looking at/considering the likes of SNG001. If they are then it would make sense based on the science (and they keep saying they're science lead) that Emergency Use would be a given....
I cannot believe logic won't prevail here...

'It's all about the Vaccine!'....is it? They're going to have to make it mandatory...there's a lot of people who simply won' have it so there has to be a treatment in place too...like good old SNG001...

'Recent polls have found as few as 50% of people in the United States are committed to receiving a vaccine, with another quarter wavering. Some of the communities most at risk from the virus are also the most leery: Among Black people, who account for nearly one-quarter of U.S. COVID-19 deaths, 40% said they wouldn’t get a vaccine in a mid-May poll by the Associated Press and the University of Chicago. In France, 26% said they wouldn’t get a coronavirus vaccine.'

Oh! and don't forget AZ knows a lot more than most about SNG001....

Caveat...being seen by fellow scientists to go down the Phase III route is good politics, but if they have Emergency Use and patients obviously benefit then perhaps the SNG001 could be expanded and Phase III cancelled or put on hold....
Phase III could also be a 3 prong...Placebo, SNG001 and SNG001 + ???
Are there any trials being set up in the US which have no recruited yet which could have SNG001 added into the mix...!!!!

Medicalstudent98...they have date from Covid Hospital Trial, and will soon have some data from the Covid Home Trail too. They also unblinded the COPD trial. Combine this with data from work done elsewhere around the World using Interferon Beta 1a, my guess is they will get Emergency Use Only for very specific cases only and also look to set up a Stage III Trial in the US with a Partner (Pharma most likely). Governments are now panicking, they absolutely cannot afford to go into lockdown again. They need people at work and buying stuff...lots of it.
As has been pointed out, time is short and Winter will soon be upon the Northern Hem...and nobody really knows what effect flu and Covid together might have...
Yes, it's good to be cautious, but....

It says not yet recruiting and both are via injection...mmm anyone got some inhalers out there which could be used instead?

They did the same the other day.. That was a much bigger drop and it was quite obvious that they were tree shaking to then sell into the US market. I suspect theyve done the same today.

'In January 2019, the US Food and Drug Administration (FDA) said its investigation had shown that although the overall risk to patients was small, it was “deeply concerned” that the contamination went undetected for so long. It said it had uncovered “systemic problems of supervision” during manufacture that could have created the conditions for quality issues to occur.

Unfortunately, this is not a ‘one off’ cautionary tale — it is the latest in a series of concerns about manufacturers among China and India, two of the world’s largest producers of pharmaceuticals.

Ongoing concerns
India is the global leader in generic drug production and manufactures 25% of all medicines in the UK[3]. A parliamentary report on the impact of Brexit on the pharmaceutical sector, published in May 2018, highlighted that 80–90% of generic medicines used in the NHS are imported, with China and India in the top five providers of UK medicines outside of the EU[4].

And this is reflected in the concerns raised by regulators. From the start of 2018 until August 2019, the FDA’s Office of Manufacturing Quality sent 75 warning letters to pharmaceutical manufacturers across the globe that appeared to have violated its safety and/or quality standards. Half (49%) of these warning letters were sent to companies based in China or India[5].'
https://www.pharmaceutical-journal.com/news-and-analysis/features/india-and-china-spark-concerns-for-uk-drug-supplies/20206998.article?firstPass=false

Surely any large Pharma could run the final trial results, together with any other info Synairgen are willing to let them see, past their in-house scientists to determine if it had value for them in either a licence format or full blown buy out.
Peer reviews are the scientific equivalent of the Oscars. If Pharma thinks there's a route to market and big money to be made they will do what ever it takes regardless....

Mr Bond... I think you'll find they've gone from 11.69% down to 10.99%
??

Funds are alway buy and selling a few shares to keep the fund looking balanced and the graph in a North Easterly direction if poss. Plus there are the effects of their customers buying into and selling out of the fund which again creates the need to rebalance. So it's not always in the hands of the Fund Manager...
It's not a vast amount and we've had some nice buy ins this week to compensate.

A treatment or treatments will have to go alongside vaccine as so many people will not have a covid vaccination unless its made mandatory.
Personally I wouldn't worry about vaccinations they don't stop flu each year and they won't stop covid popping up all the time. Vaccinations will allow Govts to get their countries back to normal again and with the full support of the likes of SNG001 keep most people out of hospital or at least out of the ICU...
Let's face it chaps, this is never going away... It will change every year as flu does and vaccines will only ever be based on last year's model...

Mr Big... I suspect it will be news coming out of the ACTIV partnership the US pulled together...
It's a bunch of big pharma and unless one or more sign a licence agreement for SNG001 then I wouldn't get hopes up on SNG001 being what Trump is referring to.

"With respect to therapeutics, I can tell you that I think over the next couple of weeks, we will have some really, very good things to say... We will have some announcements on that over the next two weeks," Trump told reporters.

https://news-abplive-com.cdn.ampproject.org/v/s/news.abplive.com/news/world/coronavirus-cure-covid-19-treatment-vaccine-good-news-in-2-weeks-says-trump-1297078/amp?amp_js_v=a3&_gsa=1&usqp=mq331AQFKAGwASA%3D#aoh=15959712815799&referrer=https%3A%2F%2Fwww.google.com&_tf=From%20%251%24s&share=https%3A%2F%2Fnews.abplive.com%2Fnews%2Fworld%2Fcoronavirus-cure-covid-19-treatment-vaccine-good-news-in-2-weeks-says-trump-1297078

23/7/2020
'GAITHERSBURG, Md. and MORRISVILLE, N.C., July 23, 2020 /PRNewswire/ — Novavax, Inc. (NASDAQ: NVAX), a late-stage biotechnology company developing next-generation vaccines for serious infectious diseases, and FUJIFILM Diosynth Biotechnologies (FDB), a world leading contract development and manufacturing organization (CDMO) for biologics, viral vaccines and gene therapies, announced today an agreement to manufacture bulk drug substance for NVX-CoV2373, Novavax’ COVID-19 vaccine candidate. FDB’s site in Morrisville, North Carolina has begun production of the first batch of NVX-CoV2373.
This arrangement falls under Novavax’ recent $1.6 billion award by the federal government as part of Operation Warp Speed (OWS), a U.S. government program that aims to begin delivering millions of doses of a safe, effective vaccine for COVID-19 to the U.S. population. '
https://fujifilmdiosynth.com/about-us/news/novavax-and-fujifilm-diosynth-biotechnologies-initiate-large-scale-manufacturing-of-covid-19-vaccine-candidate/

https://www-wsj-com.cdn.ampproject.org/v/s/www.wsj.com/amp/articles/everyones-a-day-trader-now-11595649609?

We now know SNG shares are being offered on an OTC basis in the US (OTCs are also referred to as Penny shares over there).
Interesting not in above link about commission free sites and brokers masking large trades...mmmm

Let's hope we don't get taken out for a couple of multiples of our current market price...

Yesterday it all kicked off as the US market opened up so I just think they played straight into it yesterday...using a drop and then sell into tactic.
If they think the US can still generate a few more dollars, they may try a different tack and simply drive this one up today...the FOMO over the weekend tactic.
Hey ho...we're all in it to win it...