(Adds details, background)
By John Miller and Stephanie Nebehay
ZURICH/GENEVA, April 30 (Reuters) - Pfizer aims to
make 10-20 million doses of a coronavirus vaccine it is
developing with Germany's BioNtech by the end of 2020
for emergency use depending on trial results, the U.S.
drugmaker's vaccines head said on Thursday.
The companies, which are developing four vaccine candidates,
have already dosed the first humans in Germany and hope to begin
a U.S. trial soon, pending approval by regulators.
Pfizer, BioNtech and numerous other companies and scientists
are in a global race to develop a vaccine for the virus, since
there are currently no approved treatments and therapies under
study have shown mixed results. Also on Thursday, Britain's
AstraZeneca joined forces with the University of Oxford
on a vaccine project that is also already being tested in
volunteers.
Making millions of doses available within just months, as
Pfizer hopes, would mark almost unprecedented speed for a new
vaccine and require swift regulatory action even for emergency
use.
"Of course we need to see and wait to see how the vaccine's
efficacy and safety is demonstrated, hopefully in the coming
months," Nanette Cocero, global head of Pfizer Vaccines, said on
a conference call organized by drug industry group IFPMA.
"But assuming that is demonstrated, we are looking to ramp
up manufacturing rather quickly to have around 10 to 20 mln
doses by the end of this year, which are expected to then of
course be used in an emergency type of setting."
Other drugmakers testing possible COVID-19 vaccines include
Moderna, Johnson & Johnson and Novavax
, as well as smaller projects like at Bern's Inselspital
hospital in Switzerland.
Countries are risking billions on projects that may never
prove successful, out of desperation to find a preventative
treatment for the virus that has killed more than 200,000 people
and lamed the global economy.
(Reporting by John Miller in Zurich and Stephanie Nebehay in
Geneva; writing by John Miller)