George Frangeskides, Exec-Chair at Alba Mineral Resources, discusses grades at the Clogau Gold Mine. Watch the full video here.

Less Ads, More Data, More Tools Register for FREE

Pin to quick picksVRP.L Share News (VRP)

  • There is currently no data for VRP

Watchlists are a member only feature

Login to your account

Alerts are a premium feature

Login to your account

Verona Pharma Says Ensifentrine Study Shows Positive Results

Mon, 13th Jan 2020 07:56

(Alliance News) - Verona Pharma PLC on Monday said its Phase 2b clinical trial of nebulized Ensifentrine met its primary endpoint.

The four-week Phase 2b trial of the drug in moderate to severe chronic obstructive pulmonary disease patients improved lung function at week four of the treatment.

In the trial, the drug was administered twice daily in combination with tiotropium, a treatment used in the management of chronic obstructive pulmonary disease and asthma.

The trial evaluated the effect of four different doses - 0.375 milligram, 0.75 milligram, 1.5 milligrams and 3.0 milligrams - with significant improvement in average FEV1 for the 0.375 milligram dose at 78 millilitre, and for the 3.0 milligram dose at 124 millilitres.

FEV or forced expiratory volume is the maximum amount of air that can be exhaled in one second after taking the deepest breath possible.

Verona said the drug hit its "primary endpoint" for a dose-related positive effect on lung function when compared with a group taking a placebo that has no medical benefit.

"We are delighted with these results in symptomatic COPD patients already on steady-state maintenance treatment. These data bring clarity to planning the design, including dose selection, endpoints and background therapy, of our Phase 3 program. We expect Phase 3 trials to start in the third quarter of 2020," said Verona Pharma CEO Jan-Anders Karlsson.

"We look forward to discussing these new and compelling data, together with the positive results from our previous clinical studies, in an End-of-Phase 2 meeting with the FDA planned for the second quarter," he added

By Ife Taiwo; ifetaiwo@alliancenews.com

Copyright 2020 Alliance News Limited. All Rights Reserved.

More News
29 Oct 2020 19:09

IN BRIEF: Verona Pharma Says Third Quarter Loss Widens

IN BRIEF: Verona Pharma Says Third Quarter Loss Widens

Read more
22 Oct 2020 16:01

UK Earnings, Trading Statements Calendar - Next 7 Days

UK Earnings, Trading Statements Calendar - Next 7 Days

Read more
21 Sep 2020 14:12

IN BRIEF: Verona Pharma To Delist From AIM But Remain On Nasdaq

IN BRIEF: Verona Pharma To Delist From AIM But Remain On Nasdaq

Read more
14 Sep 2020 13:13

IN BRIEF: Cambridge Cognition Hires Diurnal CFO Bungay As Non-Exec

IN BRIEF: Cambridge Cognition Hires Diurnal CFO Bungay As Non-Exec

Read more
24 Aug 2020 11:09

Verona Pharma Says Study Shows Ensifentrine Improves Lung Function

Verona Pharma Says Study Shows Ensifentrine Improves Lung Function

Read more
19 Aug 2020 10:35

Verona Pharma Makes Progress In Phase Two Of Inhaler Clinical Trial

Verona Pharma Makes Progress In Phase Two Of Inhaler Clinical Trial

Read more
14 Aug 2020 12:12

LONDON MARKET MIDDAY: Travel Stocks Suffer As UK Extends Quarantine

LONDON MARKET MIDDAY: Travel Stocks Suffer As UK Extends Quarantine

Read more
14 Aug 2020 10:56

UK WINNERS & LOSERS SUMMARY: Airlines Hit As UK Quarantine List Grows

UK WINNERS & LOSERS SUMMARY: Airlines Hit As UK Quarantine List Grows

Read more
14 Aug 2020 09:22

Verona To Trial Ensifentrine For Covid-19; First Half Loss Widens

Verona To Trial Ensifentrine For Covid-19; First Half Loss Widens

Read more
14 Aug 2020 07:45

LONDON MARKET PRE-OPEN: easyJet Raises Cash From Aircraft Sale

LONDON MARKET PRE-OPEN: easyJet Raises Cash From Aircraft Sale

Read more
17 Jul 2020 10:49

UK WINNERS & LOSERS SUMMARY: Verona Pharma Rises After Huge Fundraise

UK WINNERS & LOSERS SUMMARY: Verona Pharma Rises After Huge Fundraise

Read more
17 Jul 2020 08:29

Verona Pharma Shares Surge As It Raises USD200 Million For Drug Trial

Verona Pharma Shares Surge As It Raises USD200 Million For Drug Trial

Read more
9 Apr 2020 16:09

UK Shareholder Meetings Calendar - Next 7 Days

UK Shareholder Meetings Calendar - Next 7 Days

Read more
14 Feb 2020 10:41

UK WINNERS & LOSERS SUMMARY: RBS Plummets As Dividend Lags Consensus

UK WINNERS & LOSERS SUMMARY: RBS Plummets As Dividend Lags Consensus

Read more
3 Feb 2020 14:42

Verona Pharma Changes Top Management With New CEO, Finance Head

Verona Pharma Changes Top Management With New CEO, Finance Head

Read more

Login to your account

Don't have an account? Click here to register.

Quickpicks are a member only feature

Login to your account

Don't have an account? Click here to register.