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Pin to quick picksPureTech Share News (PRTC)

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PureTech's Alivio Gets USD3 Million Research Grant From US Military

Wed, 12th Sep 2018 13:44

LONDON (Alliance News) - Biopharmaceutical firm PureTech Health PLC said Wednesday that affiliate Alivio Therapeutics Inc secured funding for drug development.

PureTech said the grant, which was offered by the US Department of Defense, was worth USD3.3 million, and came in the form of a technology-therapeutic development award.

PureTech said that in line with its goal of developing medicines for dysfunctions of the brain-immune-gut axis, the funds will support preclinical development activities for product candidate ALV-107. This drug is being researched with a view to treating interstitial cystitis-bladder pain syndrome with Hunner's lesions.

"This grant provides further validation of the substantial opportunity to advance Alivio's inflammation-targeting technology as a new approach to address inflammatory diseases at the sites of inflammation and to potentially provide a new therapeutic option for diseases, such as interstitial cystitis, where there is a major unmet need," said Chief Scientific Officer Joseph Bolen.

PureTech shares were trading down 0.8% at 157.50 pence each on Wednesday.

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19 Mar 2024 16:57

LONDON MARKET CLOSE: European large-caps rise on eve of Fed decision

(Alliance News) - Blue-chip stock prices in Europe closed higher on Tuesday, showing little signs of nerves ahead of Wednesday's Federal Reserve decision and UK inflation reading.

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19 Mar 2024 11:16

PureTech shares jump on USD100 million tender offer proposal

(Alliance News) - PureTech Health PLC on Tuesday said it plans to return USD100 million to shareholders with a tender offer, starting after it publishes its annual report in April.

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19 Mar 2024 09:46

Puretech Health proposes $100m capital return

(Sharecast News) - Biotherapeutics company PureTech Health has proposed a capital return of $100.0m to its shareholders by way of a tender offer.

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13 Mar 2024 12:27

PureTech Health celebrates drug designation for LYT-200 from US FDA

(Alliance News) - PureTech Health PLC on Wednesday touted the efficacy of its acute myeloid leukaemia therapy, after securing a regulatory designation from the US Food & Drug Administration.

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27 Feb 2024 11:28

PureTech notes positive results from Shionogi's EndeavorRx ADHD trial

(Alliance News) - PureTech Health PLC on Tuesday noted that its founded entity, Akili Inc, has announced positive results from a phase 3 clinical trial of EndeavorRx for children with attention deficit hyperactivity disorder in Japan.

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20 Dec 2023 09:53

PureTech makes strong progress, expects "multiple catalysts" next year

(Alliance News) - PureTech Health PLC on Wednesday said it made "strong strategic and clinical progress" in 2023, and predicted "a productive and exciting" tear to come.

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1 Dec 2023 14:29

TRADING UPDATES: N4 launches investor hub; Capricorn production falls

(Alliance News) - The following is a round-up of trading updates by London-listed companies, issued on Wednesday, Thursday and Friday and not separately reported by Alliance News:

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17 Nov 2023 09:44

IN BRIEF: PureTech hails schizophrenia trial results for Karuna drug

PureTech Health PLC - Boston, Massachusetts-based FTSE 250 biotechnology company - Founded entity Karuna Therapeutics reports "positive results" from Phase 1b trial evaluating the effects of xanomeline-trospium, brand name KarXT, on 24-hour ambulatory blood pressure in adults with schizophrenia. Karuna says KarXT does not cause clinically meaningful blood pressure increases, with an average change from baseline at week eight of minus 0.59 mmHg or millimetre of mercury. Other vital signs like average diastolic blood pressure and heart rate were consistent with previous KarXT trials in schizophrenia. Adds that KarXT was generally well-tolerated, and side effects remained consistent with prior trials under the Emergent programme. Karuna in late September announced its application to the US Food & Drug Administration for approval of KarXT to treat schizophrenia; if successful, it will be PureTech's third therapeutic candidate to gain FDA approval. KarXT is also in development to treat psychosis associated with Alzheimer's disease.

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17 Nov 2023 07:58

LONDON BRIEFING: UK retail sales fall; AstraZeneca gets US approval

(Alliance News) - Stock prices in London are still set to open higher on Friday, despite October retail sales figures for the UK disappointing shortly before the opening bell.

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14 Nov 2023 10:59

PureTech Health celebrates positive results in Phase 2 anxiety trial

(Alliance News) - PureTech Health PLC on Tuesday said its therapeutic LYT-300 achieved its primary endpoint for acute anxiety reduction, in a Phase 2a trial using healthy volunteers.

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11 Oct 2023 14:22

IN BRIEF: PureTech's LYT-100 shows 50% improvement to key adverse events

PureTech Health PLC - Boston-based biotechnology company - Says LYT-100 trial shows around 50% improvement in gastrointestinal and central nervous system related adverse events in adults suffering from idiopathic pulmonary fibrosis compared to US Food & Drug Administration-approved pirfenidone. Adds data shows higher dose of LYT-100 well-tolerated with no additional incidence of GI or CNS AEs when titrated up from 550 milligrams dosage.

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4 Oct 2023 13:55

PureTech Health subsidiary receives fast track designation for VE202

(Alliance News) - PureTech Health PLC on Wednesday said its subsidiary Vedanta Biosciences has received fast-track designation for its VE202 treatment.

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28 Sep 2023 15:08

TRADING UPDATES: Rockhopper loss widens; Synectics inks new contract

(Alliance News) - (Alliance News) - The following is a round-up of updates by London-listed companies, issued on Thursday and not separately reported by Alliance News:

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27 Sep 2023 10:40

Arix Bioscience boosts net value, CEO jumping ship for PureTech Health

(Alliance News) - Arix Bioscience PLC on Wednesday said net asset value increased in its latest half year, but has since launched a strategic review due to "unfavourable" conditions while Chief Executive Officer Robert Lyne prepares to step down.

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29 Aug 2023 09:39

PureTech narrows interim loss despite "stormy market challenges"

(Alliance News) - PureTech Health PLC on Tuesday said its half-year loss narrowed, but saw its revenue fall by more than half.

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