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Advanced Oncotherapy study shows superiority of Light for cancers

Fri, 12th Mar 2021 11:05

(Alliance News) - Advanced Oncotherapy PLC on Friday said it has demonstrated the potential capability and superiority of Light in "biologically enhanced particle therapy" to treat resistant cancers.

The AIM-listed developer of next-generation proton therapy systems for cancer treatment said its findings build on research at the Mayo Clinic, which demonstrated the benefits of combining proton therapy with targeted small molecule damage repair inhibitors.

"Our Light system, due to its smaller beam size compared to legacy systems and its ability to deposit a greater level of radiation damage in a micro-target volume, is ideally suited to further contribute to the development of personalised medicines," noted Chief Clinical Officer Jonathan Farr.

Advanced Oncotherapy shares were trading 1.6% higher in London on Friday at 39.10 pence each.

By Evelina Grecenko; evelinagrecenko@alliancenews.com

Copyright 2021 Alliance News Limited. All Rights Reserved.

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2 Feb 2024 14:06

IN BRIEF: Advanced Oncotherapy eyes USD15 million tranche in February

Advanced Oncotherapy PLC - London-based provider of proton therapy for cancer treatment - Regarding its recapitalisation plan, company works alongside investor towards initial tranche of funding, which it expects to be about USD15 million to be received this month. However, it adds that there can be no guarantee that this funding will be received, nor that it will be received on time. Further, Advanced Oncotherapy says it remains in advanced talks with a third-party investor regarding a short-term loan facility which would provide the company with additional short term bridge financing.

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9 Jan 2024 14:06

IN BRIEF: Advanced Oncotherapy in advanced talks regarding loan

Advanced Oncotherapy PLC - London-based provider of proton therapy for cancer treatment - Continues to work on its recapitalisation plan with an unnamed third party investor. Says discussions are at an advanced stage but has not entered into any binding agreements with the investor, nor received any funds. This comes after it signed a non-binding term sheet with the investor in October. The investor is expected to provide funding of up to USD80 million to meet the company's cashflow requirements through to the European certification of the LIGHT System. Notes the treatment of first patients with LIGHT is now targeted for 2024 with certification of the LIGHT System to follow thereafter. Anticipates the financing to be a mixture of equity and debt financing. The firm currently owes GBP28 million to trade and other unsecured creditors and GBP41 million of financial debt.

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23 Oct 2023 18:51

IN BRIEF: Advanced Oncotherapy in talks over possible cash injection

Advanced Oncotherapy PLC - London-based provider of proton therapy for cancer treatment - Updates on financing discussions and current financial position. Signs non-binding term sheet with a third-party investor. Investor is expected to provide funding of up to USD80 million to meet the company's cashflow requirements through to the European certification of the LIGHT System. Notes the treatment of first patients with LIGHT is now targeted for 2024 with certification of the LIGHT System to follow thereafter. Anticipates the financing to be a mixture of equity and debt financing.

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3 Oct 2023 18:29

IN BRIEF: Advanced Oncotherapy results delayed, funding talks continue

Advanced Oncotherapy PLC - London-based provider of proton therapy for cancer treatment - On Friday, says it is not in a position to publish its accounts for the year ended December 31, 2022, and the unaudited interim results for the six months ended June 30, together with the 2022 annual report. Explains the 2023 interim results are contingent on the finalisation and publication of the 2022 annual report.

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17 Jul 2023 21:41

Advanced Oncotherapy plans to raise up to GBP110 million

(Alliance News) - Advanced Oncotherapy PLC on Monday announced a prospective recapitalisation and funding plan to raise up to GBP110 million.

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2 Jun 2023 19:37

IN BRIEF: Advanced Oncotherapy optimistic of securing further funding

Advanced Oncotherapy PLC - London-based particle therapy for cancer treatment company - Announces it has received a conversion notice for a portion of the convertible notes, which were issued to a French counterparty, as announced March 1 into new shares in the company. Says 10 convertible notes have been converted worth GBP50,000 at a conversion price of GBP0.25. Company also pays GBP56,702 conversion fee as the conversion price is below the nominal value of the shares. States this will be settled through the issuance of 756,020 new shares. Further, says in talks to raise further funding under the secured loan note agreement as well as through other non-dilutive financing options and is hopeful of securing additional financing during June 2023. Optimistic of a satisfactory outcome on the financing options being explored. In addition, company says it has issued convertible notes totalling GBP34,600 under its secured convertible loan note agreement.

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Advanced Oncotherapy considers US sale of business to secure funding

(Alliance News) - Advanced Oncotherapy PLC on Tuesday said it is continuing to consider funding options to allow it to complete its first Light machine and begin treating patients later this year.

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20 Mar 2023 13:06

IN BRIEF: Advanced Oncotherapy receives GBP1.2 million in funds

Advanced Oncotherapy PLC - London-based particle therapy for cancer treatment - Receives balance of funds, about GBP1.2 million, due under the secured convertible loan agreements entered into by the company with investors and directors. The balance of funds that have been received by the company includes GBP500,000 that was due to be received from Executive Chair Michael Sinclair by mid-March 2023. Currently, GBP5.0 million has been received from investors under the secured convertible loan note. Says it is also taking steps to raise additional financing.

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1 Mar 2023 21:15

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30 Dec 2022 14:33

IN BRIEF: Advanced Oncotherapy non-exec director buys 500,000 shares

Advanced Oncotherapy PLC - London-based particle therapy for cancer treatment - Non-Executive Director Michael Bradfield buys 500,000 shares at 13.17 pence, worth GBP65,825, on Thursday. Now has 8.4 million shares, a 1.6% stake.

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