RE: RNS17 Apr 2024 03:44
Thanks for the welcome WG.
Yep, I’m aware of the lack of commercialisation there and I’ll be honest, an increase in death is not a good outcome. And you couldn’t rule that out for this, although the Matins trial was a decent size and there is a lot of safety data from all studies. Regarding the efficacy here, that looks very good and they are clearly confident about what’s to come. Patients who are likely to die within 4 months showing ORR’s be it PR CR mCR or hemo improvement is unlikely by chance even with the smallish numbers thus far, but they are ongoing too which bodes well and surpassing their expected prognosis for survival without any other options, ie the current status quo.
We only need cash to see us through the end of P2
(Jan 2025), FDA guidance for the pivotal pathway and I truly believe that will be enough to secure a decent £1-3bn offer (efficacy trend continuing).
Good to see support from the EIC. Hoping they don’t raise lower but with enough cash to see us to P2 read out and FDA pivotal guidance should be a huge value driver and trigger a positive re-rate regardless of price realised, AIMO.