The latest Investing Matters Podcast episode featuring Jeremy Skillington, CEO of Poolbeg Pharma has just been released. Listen here.
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Ruck....................
"""I agree, it is a must watch. The animations were fantastic. I never realised that cancel cells could squeeze trough spaces that regular cells can't. You learn something new every day.""
Yes we do, I have actually been in those sequencing rooms at UCLH and the weekly meetings between oncologists, radiologists, and cancer nurses. There understanding is so kmuch more than we can ever gauge from here.
That particular animation I felt, as the cancer cells just exploded into action, and it has to believe that out of 35 billion cells they found the once ""rogue cancer cell"" that caused such mayhem.
We should all feel the ecitement in this area, whether it be Scancell or not, the progress that is being made since my first diagnosis almost 7 years ago now is overwhelming. There is a part in that documentary where George was having heart tests as to his suitability for immunotherapy which meant a lot to me as I failed that and sabre radiation and cryo therapy were the only options available. My brother actually saw my oncotherapist, and had four microwave ablations from the same surgeon after. They did destroy four tumours, but it was the two sarcomas that run rogue. He had gone through a lot, I just didn"t know but the one thing i got from yesterday was his words "the similarities between us were like mirrors"", not the differences. Shame we couldn"t share that, but at least I understnd why.
Surprised a few others haven"t mentioned that documentary, really interested to hear different opinions and thoughts on it.
You can watch that clip of melanoma cells amazing and frightening ability to spread here:
https://www.bbc.co.uk/programmes/p07dh96q
"cancer" cells
C7,
"I can only imagine Ruck it brought up many emotions in you, I did for me too"
Yes it did. As it happens, it is seven years today that my wife passed away so a painful anniversary.
I agree, it is a must watch. The animations were fantastic. I never realised that cancel cells could squeeze trough spaces that regular cells can't. You learn something new every day.
C7 fully aware of cancer ... which is why i highlight Rucks post the other day pointing out "all" cancer is Dire if you have not responded, but when investing you have to separate the "Moral ground" which has its own investment sector "Charities"
Scancell is a PLC not a charity as such the market requirement is for treatments that can meet an unmet need ..but behind that is fiscal prudence .. which is why rare cancers do not attract the funding like the majors, but this is the Crossover point of the charities getting involved . CRUK thou run a mix of Investment and charity funding ...
CRUK scientist are in constant research and indeed license out discovery for commercial money to invest.
and as we have seen are prepared to back great science SCIB2 over there own discoveries ... !!!
Good idea deadly, I am glad you guys have seen it, it is so relevant to Scancell, Jim Allisons work, and for anybody on a human level. Cannot stress more how important it is to watch it, and Inanaco surprised you haven"t commented on it.
Even for those who have /had family whose lives were torn about by cancer, it hit every button.
I can only imagine Ruck it brought up many emotions in you, I did for me too
IMO think it would be worthwhile Scancell retweeting that iplayer link for the documentary (with the appropriate hashtags of course!). Or maybe someone can create a new tweet to @scancellpharma with said link?
iicalvert, yes it woould be an interesting programme, but as we can see with the new targeted treatments, more patients are responding to their treatments, ever more are being put on a better treatment for themselves and in that away alone costs are falling per patient
Chelsea
Complement to excellent absolutely fascinating BBC4 story: I guess it might be an appropriate challenge for George McGavin to do a programme about NICE pricing of NHS drugs for terminal conditions.
Morning All,
Ruck, yes to an extent that impressed me but was that not the mullings of a querky biologist on a very important televised mission?
What tore my heart was the private moments with his family and particularly by himself where you could feel the terror of arriving at appointments and not being in control of your own life. A very moving dou,emtary and a front seat view for us into the world the SCIB1 combo trial is taking us
Deadly, thanks for the link, just watched it again.
C7, yes goose bumpy indeed - wow. What really impressed me was the way he presented it so factually and matter of fact when talking about something that would potentially kill him inside a year.
Sad that the lady with the stage 4 died. So sad and angry that the combo trial has been delayed. Boy, do we need them to get started. I’m with wild, I don’t care if I lose the lot (money) just get this thing nailed.
https://www.bbc.co.uk/iplayer/episode/m000696j/a-year-to-save-my-life-george-mcgavin-and-melanoma
Yet to see it myself but here's the link. As mentioned, it was on BBC 4, not 2.
Just finished watching it. Absolutely fascinating!
What was on BBC2?
D'oh.
Thanks Chelsea.
BBC2 Tonight at 9.00 also made it a very good night for BBC!
Really hoping as many of us as possible watched that documentary. For those who have and those that can still watch it , it is 32 minutes in when Immunatherapy is first mentioned and the gentlemans appointment with Jim Allison at the M.D.Anderson Centre in Houston. The enormity of what is being achieved and what we pray we can compete with is laid very bare.
From sequencing to videos of T.Cells in action and group therapies attended by patients who had stage 3/4 melanoma and are surviving 4 years on, where it is there hope as Jim Allison quoted ""We could be seeing the ""c"" word being used.
I found the science extraordinary and related to the human emotions involved and the programme encaptured that to perfection. So if anybody didn"t catch it, it was on BBC4 at 9.00, and whatever stage of research you are at it wil explain more than pages and pages of PDFs ever will. That is what we are up against and they talk about combination therapies in trials too. Wouldn"t it be something if we can achieve what is happening out there?
Goodnight, a must watch documentary.
This is the drug the man is on.......................
https://www.novartis.com/news/media-releases/novartis-receives-fda-approval-tafinlarr-mekinistr-adjuvant-treatment-braf-v600-mutant-melanoma
There is a one hour documentary about a man learning the science about his melanoma condition.
It is titled ""A year to save my Life".
Should be more than interesting.
Goodnight